Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZNF143 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713159 21840992
PLK1 CDC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21041660 1013557107
PLK1 CDC6 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 21041660 1013557107
ZNF76 TCP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10893243
ZNF143 TCP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10893243
TBP TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7666533 17967894
SP1 IRF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22307793 22464952
SP1 FHL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16624878 0602109103
SP1 ERVK-11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9261391 9420220
TBP PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18204072 10196169
CREB1 PTGS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
TBP ERVK-11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773395 2050122
TBP BRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18700021 12016223
POU5F1 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17211451
POU2F2 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9878805 19279235
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
TPP1 TERT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25172512 17237767
LIN54 NFYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 35140242
ZNF76 FHL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 33961781
POGZ NFYC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 35140242 20936779
TBP ZNF76 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15280358 16337145 16522640
CDC6 FBXW7 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
POU2F1 SP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
POLR2F TBP â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TBP HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16705163 21840992 12612066
HCFC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12670868 10976766
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
ZNF143 ESCO2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20116366
BRF2 TBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11564744 17353931 33961781 16713569
ZNF143 VAMP7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14672948
BRF2 TBP â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
BDP1 TBP â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
BDP1 BRF2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
NANOG POU5F1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
POLR2A TBP â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
HMOX1 NOS2 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17689680 22461508 23390297 6357187 8871614
CREB1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17313370 19534727 14523007
PLK1 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21041660
SP1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 24074563 19843528 19047367 15951564 10778946 21536653 19287963 12019268 11452025 19360348 18365874 14577922 19318640 14611815 12368233 15226182 15656906 21553143 15067344 21132266 11342218 16452190 21590772 19649288 17141225 12151407 16234237 17325661 18093727 19106100 18754863 1236823 10637317 21693539 22554713 19912441 11279234
SP3 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11342218 16452190 12151407 19047367 15951564 17548428 11279234
IRF3 IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15741273 15331713 10048763 10933732 11473119 8524823 9891032 17785777 19193793 9877175 22593165 10938111 11303025 12242290 21795596 24278020 23028052 19349300 10692430 27012395 11162841 24535579 12821121 16641293 20047764
SP1 SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16969077 16883603 19329185
SP1 POU2F2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11856838 9705341 8668525 1829677 9009278 9153304 1535687 1739980 12414730
SP1 NFYC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18654640 9748295 9604010 18559965
SP1 ZNF143 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11856838 9705341 8668525 1829677 9009278 9153304 1535687 1739980 12414730
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16840740 17616668 17012241 15767339 23635401 10825178
CREB1 PTGS2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11579131 15187187 15749884 16007092 16713974 17404308 20547845
SP3 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16840740 17616668 10825178 17012241
CREB1 PTGS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 20954072 21668646 15213229 11092885 18515110 19925797 22919060 17559081 16007171 17505916 17186551 15221958 11668179 11526505 24378735 20032081 17524357 16256955 19797430 16319525 21268077 15289885 17632087 17962194 14645533
TBP POLR2F â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9087428 14730212 8247010 10675336 9203586 10760173 19805548 2050122 8524864
ZNF76 TBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15280358 16522640 16337145
POLR2A POLR2F â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
POU5F1 NANOG â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20925113 17506876 16153702 20526341 19829295 22855527 17068183
POU5F1 NANOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18662995 22745796 15860457 20505756 18537119 19522013 18687992 17272500 18338330 17068183
POU2F1 ZNF143 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11856838 9705341 8668525 1829677 9009278 9153304 1535687 1739980 12414730
POU2F1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19467240 22349263 14630716 11134960 24459328
ZNF143 TPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1386897 16648583 19823669 8566747 23870664 9566870
POU2F2 ZNF143 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11856838 9705341 8668525 1829677 9009278 9153304 1535687 1739980 12414730