Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
OGG1 APEX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11139613 25086253
APEX1 OGG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20185827 17203305
APEX1 HAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17706600 1588959
TDG APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11864601
TRIM37 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CNTROB APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PICK1 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
XRCC4 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15380105 5217198
ZNF639 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATM YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FEN1 TDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
POLD1 FEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
PCNA FEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
FEN1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
FEN1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
FEN1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7876218 8131753
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
MBD4 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PNKP KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
MBD4 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
XRCC1 MPG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18971944 7294748
POLL MUTYH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0907280106 19820168
POLB NEIL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16982218 15260972
DDX20 PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
MYOZ1 PNKP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
XRCC4 PNKP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15385968 5217205
FGFR3 PNKP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PNKP TRIM37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PNKP KRTAP4-12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PNKP SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PNKP SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PNKP UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PNKP MAGEA11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53BP1 PNKP â—¼   COLOCALIZATION 2.0 0.8 intact 21637298 8199151
POLD1 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 10852724
POLE2 POLE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 32296183
POLL XRCC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18971944 7294748
SSRP1 MCM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218941 16902406
SSRP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23613959 9687513
XRCC1 TDP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19851285 7542621
XRCC6 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GEMIN4 DDX20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10725331 5212337
HBB HBA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HBB HBA2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MYOZ1 MAGEA11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YWHAZ MCM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
FGFR3 ZBTB14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL12 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PICK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DDX20 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT SNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN1 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ HNRNPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
ESR1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14695898 18252963
KLHL12 DVL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZBTB14 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPRBP UNG â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 22292079 21226479 20870715
ESR1 APEX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
XRCC6 APEX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 30585729
XRCC6 PARP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PNKP HBA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PNKP HBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
XRCC5 RFC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12393188 26344197
RFC1 XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30585729 26344197
DPOLB SSRP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
SSRP1 MCM3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21055985 16902406
SSRP1 MCM5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21055985 16902406
ESR1 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
APTX XRCC4 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
DPOLB APTX â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ESR1 KDM1A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23403292 17289570 31527615
DPOLB PARP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PNKP ATX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25590633 30994454
XRCC6 DNLI4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10757784 15520013 22990118 26496610
ESR1 MCM5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23403292 33731348 19805454 31527615
ATX3 HAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30994454 21386698
DPOLB DNLI3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
PCNA XRCC6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12171929 11239001 24695737
FEN1 POLD2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
FEN1 POLD3 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
PCNA POLE â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
PARP3 PARP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12640039 20064938
PARP1 DPOLB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 20302655 20303835 26186194
XRCC4 PRKDC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15520013 9259561 15194694 22939629 9430729
SUPT16H SSRP1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218941 16902406
HNRNPU POLR2A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
PCNA APEX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 11601988 10559261
ATM PRKDC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10608806 10464290
SSRP1 PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
PCNA PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20129057 20302655 12930846 21690293 20303835
PNKP MCM3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15385968 17353931
PNKP DNLI4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15385968 17353931
XRCC6 SSRP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 30585729
DPOLB PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12063248 25184665 14988403
HBA2 HBB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
HMGB1 SSRP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 29721183 26344197
OGG1 XRCC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12933815 16713569
CCD43 PNKP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781 26186194
XRCC6 XRCC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 30585729
DDX20 GEMIN4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CREBBP HTT â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PRKDC XRCC4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CREBBP TDG â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
LIG4 XRCC6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PCNA TP53BP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
DPOLB APEX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9207062 17803946 28986522
FEN1 APEX1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11601988
XRCC1 APTX â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 15555565 5217319
PARP1 HMGB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29721183 28190768 34079125
NEIL1 XRCC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15260972 16713569 33961781
PARP2 PARP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19629035 12217960 11948190
POLD2 POLD1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 31449058
PRKDC DNLI4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10608806 22529269 15194694
DNLI3 XRCC6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 12897160 33961781 30585729
HAP1 HTT â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PNKP XRCC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
XRCC1 APEX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19934257 28986522 16713569 11707423
APTX XRCC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 16713569 16964241 16439205 33961781 26186194 15380105
MUTYH PCNA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 26377631 11092888
PARP1 DNLI3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 12897160 24778456
DPOLB PNKP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11163244 28514442 26186194 33961781
POLG2 POLG â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6167829 17762861
TDG ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12874288 16282588
XRCC4 XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17124166 15520013 26774286 26496610
APTX XRCC1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
POLB XRCC1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
APEX1 TDG â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11889051 15823533 18805789
MUTYH APEX1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 11092888 24209961 28986522 19820168
MUTYH APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19820168 16189514 11092888
XRCC1 APTX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15380105 16713569 15555565 15044383 26496610 16964241 15367657
APTX PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15044383 16713569 15555565
MPG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17129768 14761960
OGG1 NEIL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15260972 11904416 12097317
XRCC1 NEIL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16982218 15260972 11163244
NEIL1 PNKP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16982218 15260972 11163244
NEIL1 DNLI3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 15260972 33961781
PARP1 PARG â—¼   DE_ADP_RIBOSYLATION ✅ 3.0 0.9 Reactome 17548475 21398629 15607977
XRCC1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 15555565 9584196 18971944 24778456 15044383 34111398 14500814 30260704 20302655 12897160 34079125 20303835
PARP1 XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24140708 16490787 16794079 14734561 33961781 30585729 34079125 10400681 17283121
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
PNKP XRCC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11163244 15385968 16713569 17353931 21637298 26496610 34111398 15367657 19155274
PNKP DNLI3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11163244 17353931 33961781 30994454
PNKP XRCC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15385968 28514442 32296183 17353931 21637298 33961781 26186194
POLD2 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16000169 10852724 16510448
POLE4 POLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 6693436 10801849 9405441
XRCC5 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15941674 10750018 20023628 17308091 15758953 20085707 33005030 10446239 26496610 19303849 20711232 9312071 26446488 15520013 28154079 28345663 16857680 12393188 22404984 21679440 26344197
XRCC6 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20711232 21575865 33005030 28345663 15941674 10064605 26496610 26446488 15520013 10750018 8422676 26175416 22939629 17308091 30585729 19303849 21969602
TDG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12874288 17129768
DPOLB XRCC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 29668892 16713569 25423885 15107487 26496610 15520167 34111398 33961781 26186194 8978692 11467963 15367657 11909950
DNLI3 XRCC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11163244 11352725 29668892 16713569 8264637 17353931 9705932 26496610 30260704 34111398 33961781 24981860 20227374 9136882 11909950
XRCC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 15107487 34111398 30260704 20227374
XRCC6 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15910003 19177010 28514442 28035050 14681455 10750018 17159921 25574025 17308091 10984620 11196700 32296183 7699019 33005030 15367688 12145306 19118032 10446239 26496610 19906305 26774286 10207052 21454661 18809223 9488450 26446488 15520013 30021884 22939629 17283121 10219089 10757784 21070772 11493912 21172662 15023334 22863883 22451927 21679440 24981860 10783163 33961781 30585729 26344197
XRCC4 DNLI4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25416956 22529269 21070942 17567543 9259561 22658747 23219551 32296183 15194694 10854421 25910212 15520013 11702069 31548606 11809878 9705934 10757784 30496552 33961781 26186194
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
POLD2 POLD4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
POLD3 POLD4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
POLE2 POLE4 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
UNG VPRBP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
POLE3 POLE4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
RFC2 RFC3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 9488738 26344197 24981860
PCNA POLL â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
FEN1 POLD1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
POLE POLE4 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
RFC2 PCNA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9228079 12171929 24958773 26496610 8093561
PCNA RFC3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12171929 24958773 12766176 14657243 10051561 9092549 26344197
RFC3 RFC5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 24981860 22939629 26344197
RFC5 PCNA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9228079 12171929 16189514 24958773 8999859
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219440 17159921
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
FEN1 PCNA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 17115032 7673186 8876181 1477073 14657243 16216273 26030842 31467278 26496610 11430825 12853968 26751069 32900933 22592530 8668533 26264872 11313979 30184152 24958773 24728180 11601988 9545252 9178907 15616578 9305916 18692475 29997244 22556262 15576034 33961781 26186194 22606318
PCNA RFC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12171929 12192049 22939629 9649448 15225546 24958773 12045192 26496610 10353443 8861969 30301766 9092549 8999859 12400013 26344197
RFC1 RFC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9488738 14681455 15655353 18245774 22939629 26344197
PCNA RFC4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9228079 12171929 16189514 22939629 24958773 26496610 10051561 12400013
HBA HBB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 16189514 6683087 1552945 12122004 11724557 10390349 8980683 9441940 29997244 30833564 28665412 9830011 6644819 15835899 16169070 10930828 9894000
POLG POLG2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
POLE2 POLE3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
LIG3 XRCC1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RFC1 RFC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 9488738 22939629 14681455 33961781 18245774 9092549 26344197
RFC1 RFC5 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 28514442 9488738 14681455 33961781 18245774 22939629 26344197
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
POLE POLE3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
LIG1 PCNA â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RFC3 RFC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9488738 8692848 14681455 18245774 22939629 26344197
RFC2 RFC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9228079 9751713 28514442 9488738 22939629 8692848 15655353 33961781 24981860 16582606 9092549 26344197
RFC3 RFC4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 32296183 9488738 22939629 8692848 33961781 9092549 26344197
MCM5 MCM3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15232106 28514442 16189514 12364596 26264872 25963833 12614612 22540012 11248027 23993743 22863883 27621311 33961781 25843623 30108253 22939629 26344197
POLD1 POLD4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PCNA RFC5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FEN1 PCNA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLD2 POLD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLE POLE2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RFC1 RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PCNA RFC2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RFC2 RFC4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RFC3 RFC4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SSRP1 SUPT16H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
UNG APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9724657 15479784 25086253 9200707
PARP1 APEX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 17548475 11440997 12727891 15135726 10364231 11340072 9804757
LIG1 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
PCNA APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
FEN1 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11601988 16189514
PARP1 APTX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15555565 19643912 15044383 16713569
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM TDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26421495 29216365 24947324 29078113 19851285 34181949 24493735 29718323
ATM MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15210935 17244605 30062004
ATM PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23042680 23449221 24000320 21824916 23433795 17525332
PARP1 FEN1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
POLB FEN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21183466 19778542 20573551 11440997 15731342 6278323 15193131
PCNA FEN1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
POLD1 FEN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
FEN1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PCNA FEN1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 11283614 11756412 12202749 14624239 14726013 15385537 15703371 15871698 16216273 16449207 16697054 17055429 17116323 17965729 18398454 18524993 18558713 18584027 18809224 19068479 19490890 1974050 19847258 20027199 20056333 20064462 20691907 20713526 21376743 2191300 22021614 22657828 22743550 22973052 23082994 23161013 23253856 23414611 24036544 24050180 24709898
PCNA FEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 28514442 15576034 8668533 3113402 11601988 12853968 31467278 1477073 24958773 7673186 16216273 11313979 15616578 8876181 14657243 11430825 26496610 16189514 9305916 22606318 28073635 19153658 26751069 26186194 9178907 22592530 24728180 17115032 18692475 26030842 16326861 29997244 22556262 9545252 31515488
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
PARP1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
XRCC1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
XRCC1 LIG3 â—¼   PROTEIN_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
LIG3 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9705932 20227374 17353931 11163244 26496610 16713569 8264637 11352725 9136882
PCNA NEIL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18032376
PARG PARP1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 196269035 22469522 22713970 23110147 24684389
PARG PARP2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 196269035 22469522 22713970 23110147 24684389
PARG PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22469522 22713970 196269035 17276427
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 PARP3 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 14726013 15703371 16697054 17088286 17116881 18077224 19208614 19364882 196269035 19847258 20603072 21211721 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23178593 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 PARP2 â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 18835851 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21037379 21060331 21076181 21270334 21337561 21376743 21818122 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 POLB â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 PARP2 â—¼   PROTEIN_INTERACTION 60.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 18835851 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21037379 21060331 21076181 21270334 21337561 21376743 21818122 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 PARP3 â—¼   PROTEIN_INTERACTION 27.0 1.0 ACSN 14726013 15703371 16697054 17088286 17116881 18077224 19208614 19364882 196269035 19847258 20603072 21211721 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23178593 23562323 23568489 24050180 24210699 24684389 24976506
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 POLB â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
XRCC1 PARP2 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PARP2 POLB â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 PARP2 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PARP2 POLB â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PARP3 LIG4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PARP3 XRCC4 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PARP3 LIG4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
PARP3 XRCC4 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 12471202 15703371 16439205 16697054 17088286 18077224 19346677 19473888 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
XRCC4 PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 21637298 26186194 17353931 12032095 32296183 15385968
PRKDC PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23433795 21824916 24000320
XRCC1 PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21637298 17353931 11163244 28821613 19155274 15367657 15385968 26496610 16713569
LIG1 POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
POLB POLD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLD4 POLD1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD1 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 POLD1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD1 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9286699 12403614 16510448
POLD1 POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12403614 16510448
POLD4 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
LIG1 POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
POLB POLD3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PCNA POLD3 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD3 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD3 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD2 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD3 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLB POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
LIG1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
PCNA POLD4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
PCNA POLD4 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
POLD4 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD2 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
PCNA POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24022480 9038370 16510448
PRKDC POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
LIG4 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC4 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC6 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
XRCC5 POLL â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PCNA POLL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12368291 11784855 16174846 16189514 12081642
PRKDC HNRNPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27303920 25986610 19351595 25030905 19844162
PRKDC TDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 26421495 29216365 29078113 19851285 20009512 24493735 29718323
PRKDC LIG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15194694 15941674 17570479
PCNA RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8999859 12400013 15225546 19285992 10353443 12192049 9649448 26496610 12045192 12171929 24958773 8861969 9092549
RFC5 RFC2 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 9228079 9751713 28514442 9488738 8692848 33961781 24981860 22939629 26344197
RFC5 RFC4 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 9228079 9751713 16189514 9488738 25416956 22939629 28514442 29892012 32296183 26264872 8692848 33961781 24981860 30021884 9092549 26344197
SSRP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15171726 23810005 1406642 19946334
TDG CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11864601 17129768 24748645
XRCC5 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PCNA XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
XRCC1 POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PCNA XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
XRCC1 POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
XRCC1 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15107487 26186194 8978692 16442856 15520167 11467963 26496610 15367657 25423885 16713569
PCNA POLB â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
POLB POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB LIG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9685411 12200445 19329425 8663274 11554294
POLB PCNA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PCNA POLB â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA LIG1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA POLD2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA POLD2 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611
PCNA LIG1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 11756412 14624239 14726013 15703371 15871698 16697054 16731526 17088286 17116881 19208614 19364882 1974050 19847258 20056333 20603072 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
LIG1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12171929 9649448 28073635 10559261
LIG1 POLD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9649448 19223468 22952233 10959839
LIG4 XRCC4 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
LIG4 XRCC4 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 11163244 12032095 12471202 15385968 15703371 16439205 16697054 17088286 17638872 18077224 19346677 19473888 19546231 196269035 19772495 19808869 19847258 20691907 21175350 21211721 21270334 21300785 21376743 22055391 22469522 22713970 22743550 23178593 24050180 9242410
MCM3 MCM5 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
MCM3 MCM5 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10882098 12185086 12909626 15279786 17102137 17116885 17296725 17303408 17582221 17608804 17660363 17887956 18451105 18590585 19158510 19793801 21406556 21527023 7575488
HTT CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11264541 11607033 16456924 15994095 17500595 16713569 10823891
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501