Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SEC24A TRIP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SAR1A SEC24A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30605680 11208115
FGFR3 CDS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BAG5 HSPA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20223214 15603737
ACBD3 SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF2 SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18157088 6492033
SMURF2 TNPO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PIK3R1 GAB1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 10978177 6731241
GAB1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
PIK3R1 SOS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SOS2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
QARS1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212831 10913161
PAFAH1B1 KARS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
AHSA1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16696853 20618441
HSP90AB1 AIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19375531 7021854
GRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
AP2A1 MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
SMARCA5 BAZ1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19092802 19234442
GRB2 CAMK2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
STAT1 CAMK2D â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15322115 11972023
ITCH CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12226085 5215735
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
CBL FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
CDC37 SQSTM1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 21900206 2001699 8089645
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
GRB2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAVS DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EPHA2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 7982920
FGF2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9490736 12750158
KLB FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17623664 29648978
FGFR1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9480847 16713569
STIM1 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 HSD17B12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAT1 FGFR3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16410555
FRS2 PTPN11 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
GRB2 MYO6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SMARCA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HADHB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SERPINH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 GRWD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MYO1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
HADHA TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
PAFAH1B1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
HSP90AA1 MAVS â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20628368 16394098
STAT5B HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19014541 22552610
HSP90AA1 PAFAH1B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20133715
HSP90AB1 MAVS â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20628368 16394098
STAT1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9880553 10440232
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IL6 STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8662591 8662795
IL6 STAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8662591 8662795
PLCG1 KLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16844695 10652257
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK3 SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7717053 20154642
MAPK3 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MRPS18B MRPL10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1108852108 22003127
MRPL10 MRPS9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL10 MRPS25 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL28 MRPS25 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL28 MRPS9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPS18B MRPL37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1108852108 22003127
MRPL37 MRPS9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL37 MRPS31 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL37 PTCD3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL37 MRPS22 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL37 MRPL53 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL37 MRPL43 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL37 MRPS25 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL37 MRPS7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL37 MRPS34 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL43 MRPS25 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL47 MRPS25 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL53 MRPS9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPL53 MRPS25 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MRPS22 MRPS18B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MRPS25 PTCD3 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SMC2 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
PAFAH1B1 NUDCD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16754861 0602916103
PLCG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
PIK3R1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25814554 15021914
SEC24B PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLCG1 PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
STAT1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 10022928 18508557
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
STAT1 SOCS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15240659
FGFR1 PIK3R1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
PTEN WWP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21532586 33470109 25547115
ITCH TRAF6 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
MRPL37 MRPS26 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
MRPL10 MRPL37 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
ACOT2 ACOT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FGFR1 CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18022941 31980649
CDC37 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 17525741
MDM2 CUL4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B RBM14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 21145461
EMD VAPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25910212 34079125
SDC2 FGFR3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAD21 FHL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22145905 25416956
RAD21 PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22145905 22939629
SMC2 RAD21 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22145905 17113138
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
MRPL10 MRPS22 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL10 MRPS7 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL10 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL10 MRPS31 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL10 MRPS34 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPS22 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPL43 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPL53 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPS18B â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPS31 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPS5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL28 MRPS34 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL43 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL43 MRPS34 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL43 MRPS18B â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL43 MRPL53 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL43 MRPS31 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL43 MRPS22 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL47 MRPL53 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL47 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL47 MRPS22 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL47 MRPS31 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL47 MRPS34 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL47 MRPS18B â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL53 MRPS34 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL53 MRPS22 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL53 MRPS18B â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL53 MRPS7 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL53 MRPS5 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL53 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL53 MRPS31 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPS7 PTCD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MRPL37 MRPS5 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
NUP155 NUP93 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SMC2 SMC3 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CBL ITCH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12226085 19341794
EPHA4 FGFR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16365308 18790757
STUB1 HSPA8 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16293251 5218068
SRPRB STX18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FGFR1 KAL1 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
MRPL1 MRPL28 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
HSP90AB1 UNC45A â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
MRPS5 PTCD3 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
AIP HSP90AA1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
TIMM10 TIMM8A â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HSP90AA1 TTC4 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MRPS5 MRPS9 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
FGFR1 KLB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MRPL10 MRPS26 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MRPL28 MRPS26 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MRPL43 MRPS26 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MRPL53 MRPS26 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MRPS26 PTCD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
MRPL10 MRPS5 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
STAT1 SRC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14978237 10358079 9344858 16189514
NUP155 NUP205 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
NOC2L NSA2 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS18B MRPS5 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS18B MRPS7 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS22 MRPS7 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
BAZ1A BAZ1B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11980720 31045206
GLMN CUL4B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 31973889
FGF2 FGFR3 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
SRC PLCG1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8657103 7510703 7682059 1689310 16713569 8885868
STAT3 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730629 8662591
CBL EPHA2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MRPL47 MRPS26 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MRPS26 MRPS7 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
MRPL1 MRPL47 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
NEDD4 SMURF2 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
MRPL37 MRPS18B â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
NIFK NOC2L â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
FGFR3 GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9045692 26344197
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
TRAF6 SRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22447928 10635328 16189514 29545793
MAPK3 RPS6KA3 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
MRPS18B MRPS22 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MRPS34 MRPS9 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MRPL10 MRPS18B â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
FGFR1 FRS2 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 9182757
MRPS34 PTCD3 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
MRPS34 MRPS7 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
NUP205 NUP93 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ATG5 MAVS â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22749352 17709747
CUL4B GRWD1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23238014 17041588 30945288
SOCS1 GRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10022833 29991678
PIH1D1 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PYCR1 PYCR2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NUP155 NUP93 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MRPL28 MRPS7 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MRPS25 MRPS26 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMURF1 SMURF2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
FGF2 SDC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 16982797
MRPS22 MRPS34 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CBL PLCG1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
DDX27 NIFK â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
STAT1 STAT3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MRPL1 MRPL10 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
FRS2 GRB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
TIMM10 TIMM9 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
MAPK1 STAT3 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SOS2 PLCG1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10940929 17474147
FRS2 CBL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17944804 20038681 11997436
PIK3R1 SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
GRWD1 NOC2L â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
FGFR1 FRS2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
FRS2 PTPN11 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
BMP2 SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
FGF22 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16597617
MAPK3 BAZ1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19776015
BMP2 SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
SRC CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22203672 29899407 17141222 18996392 12941616 15135048 18273061 10829062 31120930 19861161 7782294 16713569 8635998 11994282 17094785 16636290
CDC37 SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32707033 31980649 11085988
FGFR1 FGF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15548653 11030354 15096041 14613973 7520751 10950949 19627396 8868466 1722683 17086194 18199118 16829530 7730326 10574979 26267536 14505356 23597562 21693575 22539306 10748122 9174056 19696444 8609172 8692946 1697263 11786412 1709094 23597563 10490103
FGF2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9490736 29436393 12750158
PLCG1 FGFR1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8321198 6730542
FGFR1 NEDD4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19953087 21765395 25292214
PLCG1 FGFR1 â—¼   PROXIMITY ✅ 0.9 0.9 mint 8019672 20932831
FGFR1 PLCG1 â—¼   PROXIMITY ✅ 0.9 0.9 mint 8019672 20932831
FGFR3 FRS2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10629055 9660748 18373495
FGFR3 FRS2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 12767520 17496910 17673906
KLB FRS2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10629055 9660748 18373495
FRS2 PTPN11 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11447289 17673906 25772309
MAPK1 FRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12419216 12974390
GOLGA3 GOPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15951434
SH2B1 GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9742218 32296183 9856458
STAT3 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9880553 10440232 23228483
STAT3 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18266962 12559950
MAPK1 RPS6KA3 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MAPK1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18378670 7569900 14963018
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
TRAF6 MAVS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31390091 21903422 32511263 20080758 30527812 26221961 31806368 23545497 22908223 29125880 26385923 16153868 27348524
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
NEDD4 PTEN â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SRC PLCG1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
SOCS3 SOCS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17363902 14512302 9885206
STAT5B SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10821852 16306356 10359822
SOCS3 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18055217 16543409
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MRPL10 MRPL28 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
MRPL10 MRPL43 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GAB1 PIK3R1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
MRPS34 MRPS5 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
SMC1A SMC2 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
MRPS26 MRPS34 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PIK3R1 PTPN11 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSP90AA1 UNC45A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
BAZ1B SMARCA5 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
MRPS18B MRPS34 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
BANF1 EMD â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
SMC1A SMC3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
SQSTM1 TRAF6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
MRPS25 MRPS34 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
DYNC1H1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
MRPS18B MRPS25 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
MRPS26 MRPS9 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
MRPS25 MRPS9 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
MRPS25 MRPS7 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
MRTO4 NIFK â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
HSP90AA1 HSPA1B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NUP155 NUP205 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HADHA HADHB â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
PIK3R1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5217342 15556646
MRPS22 MRPS31 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
MRPS22 MRPS25 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
MRPS22 MRPS9 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
MRPS25 MRPS5 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
HSPA8 STUB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
MRPS22 PTCD3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
MRPS9 PTCD3 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
MRPL10 MRPL53 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
BAG5 HSPA1B â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
MRPS22 MRPS5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
MRPL10 MRPL47 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
MRPL43 MRPS7 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
MRPL47 MRPS7 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
MRPS31 MRPS34 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
MRTO4 NSA2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
FGF2 FGFR1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
MRPS18B MRPS26 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
MRPS22 MRPS26 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PTPN11 GAB1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6169284 14701753
GAB1 PLCG1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 24728074 8596638 11507676
PTPN11 GAB1 â—¼   DEPHOSPHORYLATION ✅ 0.96 0.96 mint 20308328 8288622
PLCG1 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21706016 7629168 10940929 16038803 9020117 16713569 9281317 7516467
AHSA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
MRPS26 MRPS31 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
TIMM10 TIMM13 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
TIMM13 TIMM9 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
MRPS25 MRPS31 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MRPS31 MRPS5 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
AHSA1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
MRPS18B PTCD3 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PLCG1 CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9234717 12941616 25241761 16467851 12061819 9712732 16713569 16503409 17372230 12803489
SMC3 SMC1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 22939629 26496610 31807710 30021884 21880767 17112726 10931856 26344197 11590136 12759374 17349791 9789013 23242214 11877376 18832153 27173435 31010829 11076961 22885700 21111234 17113138
DLST OGDH â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
GRB2 SOS2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BAZ1A SMARCA5 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MRPS18B MRPS31 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MRPL28 MRPL37 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MRPL37 MRPL47 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MRPS7 MRPS9 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MRPL28 MRPL47 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS18B MRPS9 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS31 MRPS9 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS31 PTCD3 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS5 PTCD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
NIFK NSA2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
FGFR1 PLCG1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAVS TRAF6 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
MRPS18B MRPS22 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
MRPS31 MRPS7 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
MRPS26 MRPS5 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
STUB1 UBE2N â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MRPL43 MRPS9 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MRPL47 MRPS9 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MRPS5 MRPS7 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MRPL43 MRPS5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MRPL47 MRPS5 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
SOS2 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 7629138 14679214 21706016 31980649 10940929 32062451 32203420 20936779 21988832 28514442 19380743 17474147
DYNC1H1 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
TIMM13 TIMM8A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NUP205 NUP93 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPH SMC2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
GAB1 GRB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HADHA HADHB â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
HSPA4 STUB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MRPL43 MRPL47 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MRPS5 MRPS9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC1A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GAB1 PTPN11 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL PIK3R1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TIMM10 TIMM9 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
FGFR3 GAB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
GRB2 GAB1 â—¼   PHYSICAL_INTERACTION 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
HSP90AA1 GAB1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16953218 17646646 15329413 17712310 15118073
GAB1 CDC37 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16953218 17646646 15329413 17712310 15118073
GAB1 FRS2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
GAB1 KLB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
GRB2 GAB1 â—¼   SHARES_COMPLEX 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
GRB2 GAB1 â—¼   ENZYMATIC_REACTION ✅ 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
PTEN GAB1 â—¼   REGULATES ✅ 15.0 1.0 ACSN 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523
GRB2 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 12766170 21706016 9242692 10913131 11445578 22536782 8596638 11027663 10592173 20936779 11960376 15010462 19523899 20005866 19380743 10871282 9804835 14685170 11314042
PTPN11 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 72.0 1.0 Omnipath 14701753 18577518 17145710 11453982 12582165 20308328 14665621 8596638 14982882 20473329 11027663 10592173 10788507 9658397 12024020 10068651 24728074 11134009 10194437 12855672 21442024 11323411 11940581 15574420 11278704 10871282 9804835 9632795
MAPK3 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12008033 15379552
MAPK1 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12008033 26538579 15379552 10593929
SRC GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26706435 15574420 19881549 12941962 21442024 12808090
GAB1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8596638 23331499 11507676 24728074 10871282
GAB1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 10978177 11940581 8596638 24728074 9891995 16638574 9658397 9804835 11606067 9632795
GRB2 SOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 21988832 20936779 19531499 14764585 10940929 19380743 21706016 10359574 14679214 17474147 21779497 9199344 7629138
MAPK3 KARS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28394346 29029422 19524539
AHSA1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 25036637 16696853 17145710 19875381 12604615 24462205 26693507 26804907 22315411 12504007 20226818 20159553 22504172
AP2A1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12577067
BANF1 EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25910212 22399800 11792822 25502805 17620012 31515488 32814053 32296183 12163176 11792821 16189514
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
CBL CDC37 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
FRS2 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20038681 11997436
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
CBL PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7517397 9712732 12941616 25241761 12061819 23109003 9234717 16503409 11709089 16713569 17372230 16467851 12803489
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 98.0 1.0 Omnipath 9092574 19190244 16289966 11406619 7642581 11133830 10358153 8941725 9234717 8612729 11157475 10620516 16713569 21203488 11418612 24113870 17635922 18374639 14530346 11526404 8662998 8995358 11030146 9890970 9541596 11042121 15581361 9890943 8080844 7791764 9178909 15107835 8995243 8695807 9988765 23109003 11944898 15556646 17237826 10025673 17722974 8621719 16135792 16107703 16219545 9461587 9160881 9414268 16982329 19861161 10514377 9918857 11087752 9092538 11994282 9259313 15790353 19531499 9174058 8702998 25814554 22315502 19380743 10918571 8896416
PLCG1 CDC37 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17177598 16187797 15284455 16953218 17712310
CDK1 SQSTM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26279575 22424619 23856904 20974803 29423120 17570479 28963527
CDK1 STIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19881501 22748319
CDK1 NIFK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11342549 16244663 25826659
SRC CHRNA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16251431
RAB6A DYNC1H1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
PAFAH1B1 DYNC1H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11889140 11163259 27173435 12885786 19622634 26496610 36692009
RAB6A DYNC1LI1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
EIF2S1 EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
SRC EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 25008017 24609268 19789182 29684168 24365856 17637040
SRC EPHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24457997 28957431 26788993
STAT3 FGF2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
FGF2 PLAU â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11874475 18232728 18633355 18776941 19508171 19631971 21098712 22652804 23123598 25374926 9242465
FGF2 FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11874475 18232728 18633355 18776941 19508171 19631971 21098712 22652804 23123598 25374926 9242465
STAT1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16494848 23086340 19556344
FGF2 SDC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20382221 8621465 16982797 1101561416982790 8609172 11015614
FGF2 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 17145710 15096041 8868466 10490103 16597617 11030354 23597562 1722683 14613973 17086194 14505356 9174056 7730326 25772309 11786412 16829530 10950949 23597563 10574979 26267536
FGF2 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 22298955 16597617 866304410574949 9045692 15780951 10574949 8663044 25772309
FGFR1 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR1 FRS2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12767520 17496910 17673906 25467007
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
MAPK3 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27342992 23405013 18411303
FGFR1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17081983 20932831 1656221 16126727 15592455 9660748 19665973 7991458 1689310 8321198 8050374 16153436 17496910 25241761 16038803 10459043 23063561 1708307 7682059 15144186 12601080 9052794 8885868 8657103 15212693
FGFR1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 11447289 19615955 16488589 6321473 11997436 12040186 19568798 15567848 15173823 14585353 15199124
FGFR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17496910 18412956 25241761 15117958
FGFR1 FRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 11447289 11777939 11997436 11877385 12040186 9660748 15173823 25394172 23331499 6321473 16189514 19568798 14585353 17496910 9632781 10629055 21765395 11274345 15574420 9182757 11090629 15567848 16488589
PLCG1 FGFR3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 19147536 16091734 10652257 10918587 19749790 18337450 16844695
FGFR3 PIK3R1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
FGFR3 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR3 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR3 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17496910 12601080 17081983 16038803 1689310 1708307 7682059 15144186 8885868 16126727 15592455 8657103 16153436
FGFR3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 19901323 10918587 9305919 8272872 12626508 16497976 15592455 17389395 12576423 11350938 11294897 12244095 9083098 8626374 9566874 11940572 11429593 14551213 11850821 17016520 9582023
FGFR3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 11839738 10918587 11447289 11997436 12040186 15173823 7543024 15322115 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 19088846 10748192 7657660 12817007 9355737 19615955 11152457 15567848 7592750 16488589
GRB2 FRS2 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11777939 11997436 12040186 12175651 12640133 14585353 15173823 15567848 15574420 15863030 16102570 16488589 16582911 16887996 17496910 17673906 19449109 19568798 24027568 25772309 26552706 6321473 7510700 8551221
MAPK1 FRS2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
GRB2 FRS2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11777939 11997436 12040186 12175651 12640133 14585353 15173823 15567848 15574420 15863030 16102570 16488589 16582911 16887996 17496910 17673906 19449109 19568798 24027568 25772309 26552706 6321473 7510700 8551221
MAPK3 FRS2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
GRB2 FRS2 â—¼   DOWN_REGULATES ✅ - 30.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11777939 11997436 12040186 12175651 12640133 14585353 15173823 15567848 15574420 15863030 16102570 16488589 16582911 16887996 17496910 17673906 19449109 19568798 24027568 25772309 26552706 6321473 7510700 8551221
FRS2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8780727 9182757 12974390 11997436 16189514 12402043
FRS2 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 10650943 9632781 11360177 11447289 29997244 12974390 16189514 25159185
MAPK1 GORASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19651622 17081983 18767875 20068231 17287340 16713569 19413330 11408587
STAT5B GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 KLB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PTEN GRB2 â—¼   REGULATES ✅ 15.0 1.0 ACSN 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523
PTEN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
HSP90AA1 PLCG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17177598 16187797 15284455 16953218 17712310
STAT1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9880553 21430289 12940076 10440232
STAT3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18266962 16189514 12559950
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
MAPK1 IL17RD â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAPK3 IL17RD â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
PTPN11 IL6 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 27557510 9751747
IL6 STAT3 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
STAT1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 8683127 24242046 23675777 19703987 7619083 18616672 24012417 20693420
STAT3 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22927445 22363173 19797626 22547075 18765795 18616672 23954444 20493732 19751774 22105366 10391682 24315995 20930550
IL6 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 26291658 30185178 20185553 28222632 11322950 30143645 27074565 28687744 21538419 16278387 28128332 24496235 26166037 21625597 20371721 25750173 29330478 19962667 26010889 24513872 29702530 25881314 24078775 27866206 24619648 27840174 19380824 24661007 11728826 21619877 11056211 17142955 26417930 29270528 18611949 25452693 27795451 16520748 26843613 29807795 21442031 26893580 26061710
ITCH MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19881509 27736772
MAPK1 KLB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAPK3 KLB â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
PIK3R1 KLB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
MAPK1 STIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25562429 22298426 23687376 24114840 19881501 33023909 25447552 28935720
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21988832 18156174 12016217 25241761 12832467 23602568 8939914 10480933 9915826 17906627 10980595 10856237 19282669
MAPK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 18448488 19413330 11335711 9343414 15465816 25584415 12576423 11350938 20068231 12681450 12763138 9872331 11780390 18491316 18669648 11404481 10521505 18691976 20058876 15979846 14551213 10446219
MAPK3 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18156174 25241761 12832467 8939914 9915826 17906627 10980595 10856237 19282669
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
STAT3 MMP9 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15247301 18028425 19965686 10817568 19616522
NEDD4 PTEN â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17218260 17218261 17996703 18562292 19652529 22679284
NEDD4 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17218261 23331499 21071413 18307411 17218260 18562292 18498243 19345329 19652529 30594392
RAB6A PAFAH1B1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
STAT3 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733515 24218138 23963458 15793565 16293640
PTPN11 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 11593409 18950707 15790353 23109003 16371368 17722974 22315502 16107703 9660791 9918857 8080844 9632795 10973965
PTEN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PLCG1 SRC â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
PLCG1 SRC â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
SRC PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 8388373 16497976 16126727 16713569 17389395 1689310 20068231 17570479 16153436 16038803 1708307 7682059 7510703 18594017 12601080 8885868 8657103 17016520
SRC PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24830552 22891331 12869565 21532586
PTPN11 STAT1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10358138 11447289 11572860 12138178 12270932 12707331 15240681 15699106 15713798 19833085 9751747
SOCS3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12403768 17138568 11356008 10777583
PTPN11 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10409724 23331499 18508557 12040451 16189514 11594781
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
PTPN11 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 18508557 12270932 18832710 18988627
PTPN11 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10617656
SRC RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18156174 12601080
STAT1 SOCS1 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12438448 10820262 12193701 19482358 24963279
STAT3 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18843197 14630083 16432158 20003295 20357037 10809230
STAT3 SOCS3 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
STAT1 SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19122651 15339920 10359822 19115200 19643666 14742442 17091494 12639901 17558387
STAT3 SOCS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 18489773 22179221 15184887 21994466 20032196 12565872 11682619 23782265 22943202 19628067 23335796 12639901 18571793 23104276 16293640 23027374 22739025 21098664 11788008 18237746 19535626 23303450 20357037 16783372 22575502 16709613 14688368 19332118 23439558 10359822 19910459 19759305 11159537 16300827 16718380
TRAF6 SQSTM1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11274345 12620219 14660645 15125833 15340068 15721744 16252010 17948050 18264787 18758450 18922473 19161412 20531300 21981924 25002027 26587781 28574505
TRAF6 SQSTM1 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11274345 12620219 14660645 15125833 15340068 15721744 16252010 17948050 18264787 18758450 18922473 19161412 20531300 21981924 25002027 26587781 28574505
SQSTM1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 15870274 27458013 10747026 27681126 16079148 16189514 18382763 16874300 11244088 17389358
SRC STAT3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 16472776 17192274 19930715 22131018 22677902 23589069 23691193 24030100 24403062 25687758 27036022 27452906 29556339
SRC STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 11839738 10918587 9344858 7543024 15322115 10358079 14978237 11294897 7690989 16189514 12637327 11438544 10748192 7657660 12817007 9355737 11152457 10982844 7592750
SRC STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19438593 12429742 17997837 12621061
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
STAT1 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT1 STAT3 â—¼   DOWN_REGULATES ✅ - 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19122651 17558387 22693070
STAT3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25609649 8662591 12070153 31462771 25241761 11722592 8710878 9794795 23268184 15284024 16189514 9535918 11594781
STAT3 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368