ABL1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
OGG1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11139613
25086253
|
APEX1
|
OGG1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20185827
17203305
|
TDG
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11864601
|
XRCC6
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18710944
|
RPA2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10882098
10757793
|
NBN
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25558984
22231403
|
CDK2
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25558984
22231403
|
CDK2
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10882098
10757793
|
CDK2
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25558984
22231403
|
FEN1
|
TDP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
POLD1
|
FEN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
PCNA
|
FEN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
FEN1
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
FEN1
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
FEN1
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7876218
8131753
|
RPA1
|
FEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15592449
|
CRK
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PLCG1
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
HSP90B1
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HSPA5
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
LIG3
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
LIG3
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
STUB1
|
LIG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18313385
|
TOP1
|
LIG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
13679147
|
H1-2
|
LIG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18250087
|
XRCC1
|
MPG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18971944
7294748
|
POLL
|
MUTYH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907280106
19820168
|
RAD50
|
NBN
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7114538
19197236
|
POLB
|
NEIL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16982218
15260972
|
H3C2
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20080577
0913709107
|
PARP1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1429884
|
PARP1
|
H1-2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18250087
|
PARP1
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18025084
|
PARP2
|
TOP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20875401
|
PLCG1
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6805619
9020117
|
LRRK2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
THRA
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16966610
0601600103
|
PIK3R1
|
THRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0510849103
16446424
|
POLD1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
POLD1
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
10852724
|
WRN
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10781066
|
POLE2
|
POLE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
32296183
|
HSPA5
|
POLK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
LMNA
|
POLK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HSP90B1
|
POLK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
POLL
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18971944
7294748
|
RAD50
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RAD50
|
MRE11
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7114538
19197236
|
MRE11
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21052091
8081463
|
STUB1
|
LMNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
STUB1
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
STUB1
|
POLB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18313385
|
STUB1
|
XRCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18313385
|
XRCC1
|
TDP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19851285
7542621
|
H2AX
|
XRCC1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19851285
7542621
|
H3C2
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20080577
0913709107
|
H3C2
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20080577
0913709107
|
H1-2
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CBX8
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18927235
0805317105
|
CBX8
|
BMI1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17332741
5219708
|
CRK
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PTPRH
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15850787
|
H3C2
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HDAC6
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
H3C2
|
ATXN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HDAC6
|
HSP90B1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19158084
|
H1-2
|
HSP90B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SRF
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11003651
11158291
|
THRA
|
THRB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
1782215
17761769
|
H1-2
|
EPHB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2AX
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
6805208
18583988
|
MRE11
|
H2AX
|
â—¼ COLOCALIZATION
|
✅
|
|
0.81
|
0.81
|
mint
|
22157895
8303386
|
LRRK2
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
XRCC6
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
9798959
25852190
|
XRCC6
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
30585729
|
MRE11
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
24981860
|
BMI1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20668194
34316702
|
XRCC6
|
PARP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
H2AX
|
PARP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
H2AX
|
RAD50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16377563
19234442
31501894
15201865
10959836
18583988
|
XRCC5
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12393188
26344197
|
RFC1
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30585729
26344197
|
WDR76
|
RPA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27248496
31353912
|
WDR76
|
LMNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27248496
31353912
|
LRRK2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
BMI1
|
LMNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26468281
34316702
|
BAX
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19177010
21042904
19118032
19247369
15205477
25299772
18784078
|
WDR76
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27248496
31353912
25817432
|
WDR76
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27248496
31353912
25817432
|
H2AX
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21679440
18406329
20085707
|
SOX2
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21280222
35140242
23667531
|
BMI1
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20668194
24457600
34316702
|
H2AX
|
LMNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20000738
25948554
23658700
|
MMGT1
|
EMC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
32439656
22119785
26496610
27342126
33961781
26186194
|
FEN1
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
837.0
|
0.83
|
STRING
|
36370105
|
LMNA
|
MDC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
30179224
22412018
30419336
|
LMNA
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
30419336
22412018
25948554
29568061
|
XRCC5
|
TOP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28415827
21679440
|
PCNA
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12171929
11239001
24695737
|
LMNA
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
30419336
24623722
29753763
|
CRK
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23397142
10962563
12615911
|
FEN1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
FEN1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
PCNA
|
POLE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
PARP3
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12640039
20064938
|
XRCC5
|
WRN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
10783163
5212534
|
WRN
|
XRCC5
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.85
|
0.85
|
mint
|
10783163
5212534
|
H2AX
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
23145133
15613478
33961781
18406329
20224553
|
SRC
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
1689310
7510703
16713569
7682059
8657103
8885868
|
PCNA
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16189514
11601988
10559261
|
H2AX
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
6805208
18583988
|
H2AX
|
NBN
|
â—¼ COLOCALIZATION
|
✅
|
|
0.86
|
0.86
|
mint
|
22565321
8391733
|
NBN
|
H2AX
|
â—¼ COLOCALIZATION
|
✅
|
|
0.86
|
0.86
|
mint
|
22157895
8303386
|
PCNA
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20129057
20302655
12930846
21690293
20303835
|
WRN
|
XRCC6
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.86
|
0.86
|
mint
|
10783163
5212534
|
OGG1
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12933815
16713569
|
WDR76
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
27248496
31353912
25817432
|
WRN
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20802463
15733840
|
XRCC6
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
30585729
|
SOX2
|
FOXC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
35140242
23667531
28794006
|
BAX
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
AIM2
|
PYCARD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CRK
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
ABL1
|
PLCG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10708759
1383690
17474147
|
FEN1
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
11601988
|
XRCC1
|
APTX
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
15555565
5217319
|
FEN1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
12853968
|
PARP1
|
HMGB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29721183
28190768
34079125
|
NEIL1
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15260972
16713569
33961781
|
PARP2
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19629035
12217960
11948190
|
WRN
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14734561
14596914
|
POLD2
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
31449058
|
H2AX
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16377563
19234442
31501894
22157895
15201865
12419185
18583988
|
GATA4
|
SRF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11158291
11003651
|
ATXN3
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
NBN
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
PARP1
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
CRK
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
XRCC5
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
ABL1
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
POLD1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
RPA1
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
PNKP
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
XRCC1
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19934257
28986522
16713569
11707423
|
MUTYH
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
26377631
11092888
|
H2AX
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16377563
20000738
27728808
33961781
28796254
18406329
28242625
16522924
20085707
|
POLG2
|
POLG
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
6167829
17762861
|
WRN
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12177300
11328876
26496610
14734561
12937274
21679440
10880505
10783163
|
MRE11
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
30585729
10508516
26344197
|
UHRF2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21952639
28951215
27114453
|
APTX
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
PIK3R1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
LMNA
|
TMPO
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
POLB
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
MDC1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
SRC
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11494128
17474147
12522270
11781820
17318191
|
APEX1
|
TDG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11889051
15823533
18805789
|
MUTYH
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
11092888
24209961
28986522
19820168
|
MUTYH
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19820168
16189514
11092888
|
XRCC1
|
APTX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15380105
16713569
15555565
15044383
26496610
16964241
15367657
|
APTX
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15044383
16713569
15555565
|
UHRF2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21952639
15178429
33876395
|
PCNA
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10930425
|
WRN
|
FEN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16326861
12356323
11598021
14657243
14688284
|
MDC1
|
RAD50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
30179224
29656893
14519663
12607005
12607003
18583988
|
MDC1
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21622030
16377563
19234442
28242625
32518374
20159462
21676867
12475977
14519663
15201865
12607005
21293379
30598506
18001825
29499138
26734725
18001824
18583988
|
MDC1
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15377652
30179224
12607003
18678890
29656893
27590578
25064736
20460517
19804756
23115235
14519663
15201865
12607005
20224574
18001824
18583988
|
MDC1
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
30179224
29656893
20081839
14519663
12607005
12607003
18583988
|
NBN
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
NBN
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
NBN
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11110662
18583988
15733840
16377563
31501894
20081839
23145133
22157895
22941933
21676867
16932743
15201865
18001825
18001824
12419185
|
NBN
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
30179224
11238951
17612497
22941933
23530059
15758953
11062235
10426999
19244116
10783165
18458108
21884979
22464731
33558481
24413181
26455393
12447395
12679336
28369484
22078559
34038735
22231403
12419185
22939629
34348893
17526493
12861053
17500065
12750284
9705271
28363998
30440001
24981860
19270065
12607003
15734743
|
OGG1
|
NEIL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15260972
11904416
12097317
|
XRCC1
|
NEIL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16982218
15260972
11163244
|
NEIL1
|
PNKP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
16982218
15260972
11163244
|
PARP1
|
PARG
|
â—¼ DE_ADP_RIBOSYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17548475
21398629
15607977
|
XRCC1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
15555565
9584196
18971944
24778456
15044383
34111398
14500814
30260704
20302655
12897160
34079125
20303835
|
TOP1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
34079125
15247263
15848144
|
PARP1
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24140708
16490787
16794079
14734561
33961781
30585729
34079125
10400681
17283121
|
PARP1
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24140708
16490787
21575865
16794079
14734561
21679440
34079125
10400681
17283121
20085707
|
PNKP
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11163244
15385968
16713569
17353931
21637298
26496610
34111398
15367657
19155274
|
POLD2
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16000169
10852724
16510448
|
POLE4
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
6693436
10801849
9405441
|
RPA3
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RBBP8
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17965729
21052091
|
RPA1
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
WRN
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
10871373
12750383
12633936
20600238
|
WRN
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
12177300
11328876
26496610
14734561
33961781
10880505
10783163
30585729
|
XRCC1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
15107487
34111398
30260704
20227374
|
XRCC6
|
XRCC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15910003
19177010
28514442
28035050
14681455
10750018
17159921
25574025
17308091
10984620
11196700
32296183
7699019
33005030
15367688
12145306
19118032
10446239
26496610
19906305
26774286
10207052
21454661
18809223
9488450
26446488
15520013
30021884
22939629
17283121
10219089
10757784
21070772
11493912
21172662
15023334
22863883
22451927
21679440
24981860
10783163
33961781
30585729
26344197
|
CBX8
|
BMI1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21282530
34316702
20543829
10825164
20601937
19636380
26496610
27705803
22325352
33961781
24981860
17332741
24457600
|
SRC
|
PLCG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15879121
20807769
11600407
|
PARP1
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
CBX8
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
WRN
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
POLD2
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
MDC1
|
NBN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
RPA3
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
24126761
|
POLD3
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
POLE2
|
POLE4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
NBN
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
POLE3
|
POLE4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HuRI
|
32296183
|
RFC2
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
22939629
9488738
26344197
24981860
|
RPA1
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
WRN
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
PCNA
|
UHRF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
BMI1
|
CBX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
RPA2
|
UNG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
PCNA
|
POLL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
PCNA
|
TOP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
FEN1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
POLE
|
POLE4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
PCNA
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12361598
28514442
26496610
29510343
9545286
33961781
26186194
7903056
21319273
10930425
|
RFC2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9228079
12171929
24958773
26496610
8093561
|
PCNA
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12171929
24958773
12766176
14657243
10051561
9092549
26344197
|
RFC3
|
RFC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
33961781
24981860
22939629
26344197
|
RFC5
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9228079
12171929
16189514
24958773
8999859
|
RPA1
|
RPA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
24207024
22939629
26399832
26496610
24981860
16514417
19214185
26344197
|
XRCC6
|
XRCC5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5219440
17159921
|
XRCC5
|
XRCC6
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.96
|
0.96
|
mint
|
10783163
5212534
|
CBX8
|
BMI1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5219708
17332741
|
BMI1
|
CBX8
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
5219708
17332741
|
ABL1
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
9747873
11380621
15696159
8875975
9480911
21602891
18835194
18619508
12384576
8194526
11956190
19380743
24412932
9642287
17474147
8978305
12097319
17515907
33961781
12198159
7926767
|
FEN1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
17115032
7673186
8876181
1477073
14657243
16216273
26030842
31467278
26496610
11430825
12853968
26751069
32900933
22592530
8668533
26264872
11313979
30184152
24958773
24728180
11601988
9545252
9178907
15616578
9305916
18692475
29997244
22556262
15576034
33961781
26186194
22606318
|
NBN
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
20224574
7891431
|
H2AX
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
6805208
18583988
|
RAD50
|
NBN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
30179224
12607003
12124328
11238951
17612497
22941933
23530059
24651726
15758953
11062235
10426999
10783165
22464731
19197236
12447395
12679336
26215093
22939629
34348893
17526493
17500065
9705271
16391231
30440001
24981860
26344197
15734743
|
PCNA
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
12192049
22939629
9649448
15225546
24958773
12045192
26496610
10353443
8861969
30301766
9092549
8999859
12400013
26344197
|
RFC1
|
RFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9488738
14681455
15655353
18245774
22939629
26344197
|
PCNA
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9228079
12171929
16189514
22939629
24958773
26496610
10051561
12400013
|
POLG
|
POLG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
EMC2
|
MMGT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
POLE2
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
LIG3
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
ABL1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
RFC1
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
9488738
22939629
14681455
33961781
18245774
9092549
26344197
|
RFC1
|
RFC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
9488738
14681455
33961781
18245774
22939629
26344197
|
POLE
|
POLE3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
RPA1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
LIG1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
RAD50
|
MRE11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
30179224
12607003
30733337
10888888
23530059
24651726
11062235
17694070
10783165
31501894
33558481
19197236
24413181
26455393
10508516
16163361
28369484
26215093
34038735
8756642
22939629
34348893
17500065
12750284
9705271
16391231
27173435
28363998
24981860
19270065
11504724
26344197
15734743
|
RFC3
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
9488738
8692848
14681455
18245774
22939629
26344197
|
RFC2
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
9228079
9751713
28514442
9488738
22939629
8692848
15655353
33961781
24981860
16582606
9092549
26344197
|
RFC3
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
32296183
9488738
22939629
8692848
33961781
9092549
26344197
|
CDK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
POLD1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
FEN1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
POLD2
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
POLE
|
POLE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RFC1
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RPA1
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RFC2
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RFC3
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
XRCC5
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ABL1
|
CRK
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
10837221
15459660
18835194
21051857
21199784
21435002
|
SRC
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
19901323
10964922
16497976
20841568
16787943
17570479
17318191
11847100
10500097
12522270
18691976
11494128
11781820
16076903
20168609
12748290
16464493
12445832
19369195
17474147
|
ABL1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
100.0
|
1.0
|
Omnipath
|
8978305
9747873
9480991
19426560
17081983
23124138
16522685
16713569
20841568
18768933
8875975
25860930
21779437
19534553
16187300
17515907
21602891
16267043
20068231
10592173
17570479
8194526
7926767
11080615
25381819
12198159
9642287
15696159
18619508
18835194
11956190
22848689
11314030
9480911
19001122
19402756
20697350
12384576
24412932
7542925
11380621
12799422
19380743
12955086
17474147
17016520
|
ABL1
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12944467
20841568
|
ABL1
|
TOP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15448168
20841568
|
ABL1
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
10708759
19290927
12652307
1383690
16525023
8657103
20841568
17474147
|
UNG
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9724657
15479784
25086253
9200707
|
RPA2
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
PARP1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
17548475
11440997
12727891
15135726
10364231
11340072
9804757
|
LIG1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
RPA1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
PCNA
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APEX1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
FEN1
|
APEX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11601988
16189514
|
PARP1
|
APTX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15555565
19643912
15044383
16713569
|
PYCARD
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
14730312
19062087
19104081
19968986
26885855
27048821
27066895
27984721
|
PYCARD
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16964285
19062087
14730312
19968986
|
CDK2
|
RPA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
CDK2
|
UHRF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17145710
33876395
21952639
15178429
|
CDK2
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23623683
33097710
27308383
24236237
19202191
24982848
25956864
22743550
|
CDK2
|
LIG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17040896
|
CDK2
|
LIG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12851383
10930425
|
RPA2
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
PARP1
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
WRN
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
11283614
11756412
12202749
14624239
14726013
15385537
15703371
15871698
16216273
16449207
16697054
17055429
17116323
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19847258
20027199
20056333
20064462
20691907
20713526
21376743
2191300
22021614
22657828
22743550
22973052
23082994
23161013
23253856
23414611
24036544
24050180
24709898
|
RPA1
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
RPA3
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
POLB
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
21183466
19778542
20573551
11440997
15731342
6278323
15193131
|
PCNA
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
11283614
11756412
12202749
14624239
14726013
15385537
15703371
15871698
16216273
16449207
16697054
17055429
17116323
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19847258
20027199
20056333
20064462
20691907
20713526
21376743
2191300
22021614
22657828
22743550
22973052
23082994
23161013
23253856
23414611
24036544
24050180
24709898
|
POLD1
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
NBN
|
FEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
FEN1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
FEN1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
FEN1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
FEN1
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
WRN
|
FEN1
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
11283614
11756412
12202749
14624239
14726013
15385537
15703371
15871698
16216273
16449207
16697054
17055429
17116323
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19847258
20027199
20056333
20064462
20691907
20713526
21376743
2191300
22021614
22657828
22743550
22973052
23082994
23161013
23253856
23414611
24036544
24050180
24709898
|
PCNA
|
FEN1
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
11283614
11756412
12202749
14624239
14726013
15385537
15703371
15871698
16216273
16449207
16697054
17055429
17116323
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19847258
20027199
20056333
20064462
20691907
20713526
21376743
2191300
22021614
22657828
22743550
22973052
23082994
23161013
23253856
23414611
24036544
24050180
24709898
|
WRN
|
FEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
14657243
12356323
11598021
16326861
10893179
14688284
|
PCNA
|
FEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
28514442
15576034
8668533
3113402
11601988
12853968
31467278
1477073
24958773
7673186
16216273
11313979
15616578
8876181
14657243
11430825
26496610
16189514
9305916
22606318
28073635
19153658
26751069
26186194
9178907
22592530
24728180
17115032
18692475
26030842
16326861
29997244
22556262
9545252
31515488
|
PARP1
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
XRCC1
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
WRN
|
LIG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
38.0
|
1.0
|
ACSN
|
11283614
11900249
12202749
12648680
14726013
15385537
15703371
16449207
16697054
17055429
17116323
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19362533
19490890
19809470
19847258
20027199
20056333
20064462
20211143
20691907
20713526
21376743
2191300
22657828
22743550
23082994
23161013
23253856
24036544
24050180
24709898
|
WRN
|
LIG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
38.0
|
1.0
|
ACSN
|
11283614
11900249
12202749
12648680
14726013
15385537
15703371
16449207
16697054
17055429
17116323
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19362533
19490890
19809470
19847258
20027199
20056333
20064462
20211143
20691907
20713526
21376743
2191300
22657828
22743550
23082994
23161013
23253856
24036544
24050180
24709898
|
XRCC1
|
LIG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
PARP1
|
LIG3
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
17088286
17116881
17884153
18524993
19208614
19362533
19364882
19809470
19847258
20056333
20211143
20227374
20603072
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
8264637
8978692
|
LIG3
|
XRCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9705932
20227374
17353931
11163244
26496610
16713569
8264637
11352725
9136882
|
XRCC5
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
RAD50
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
59.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
XRCC6
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
RAD50
|
MDC1
|
â—¼ SHARES_COMPLEX
|
|
|
59.0
|
1.0
|
ACSN
|
11331603
11850621
11877377
12086603
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20723763
21376743
22743550
23847781
24050180
7575488
9407949
9488723
|
H2AX
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
21676867
14519663
18001824
21293379
16427009
16377563
18583988
21622030
18001825
12607005
19234442
20159462
15201865
|
MDC1
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17145710
15201865
20460517
23115235
14519663
18001824
18678890
19804756
18583988
19230643
12607003
12607005
20224574
|
NBN
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
NBN
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
MRE11
|
NBN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
17145710
22464731
26455393
12861053
17500065
15734743
12419185
19270065
22078559
19244116
21884979
12679336
11238951
12607003
9705271
17713585
10783165
12447395
10426999
18458108
15758953
|
PCNA
|
NEIL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18032376
|
WRN
|
NEIL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17611195
20346739
|
PARG
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
196269035
22469522
22713970
23110147
24684389
|
PARG
|
PARP2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
196269035
22469522
22713970
23110147
24684389
|
PARG
|
PARP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
22469522
22713970
196269035
17276427
|
PCNA
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
PARP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
14726013
15703371
16697054
17088286
17116881
18077224
19208614
19364882
196269035
19847258
20603072
21211721
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23178593
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
PARP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
18835851
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21037379
21060331
21076181
21270334
21337561
21376743
21818122
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
25642960
25789972
11440997
25643323
20483915
25642963
15135726
16012167
11340072
|
PARP1
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
70.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11900249
11948190
12032095
12202749
12637553
12648680
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19748837
19809470
19847258
20027199
20056333
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11756412
11948190
12032095
12202749
12637553
14624239
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18087292
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
1974050
19748837
19772495
19847258
20027199
20064462
20211143
20227374
20478261
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22021614
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23414611
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
PARP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
18835851
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21037379
21060331
21076181
21270334
21337561
21376743
21818122
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
PARP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
27.0
|
1.0
|
ACSN
|
14726013
15703371
16697054
17088286
17116881
18077224
19208614
19364882
196269035
19847258
20603072
21211721
21270334
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23178593
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11756412
11948190
12032095
12202749
12637553
14624239
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18087292
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
1974050
19748837
19772495
19847258
20027199
20064462
20211143
20227374
20478261
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22021614
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23414611
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
WRN
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
XRCC1
|
â—¼ SHARES_COMPLEX
|
|
|
70.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11900249
11948190
12032095
12202749
12637553
12648680
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19748837
19809470
19847258
20027199
20056333
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
LIG1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
WRN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
71.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15211575
15385537
15385968
15498778
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19654615
19748837
19847258
19892829
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24089143
24095737
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
TOP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
20875401
15911331
15848144
14699148
15247263
|
PARP1
|
XRCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9592149
18971944
15555565
19643912
15044383
14500814
16713569
24778456
12897160
20303835
20302655
9584196
|
WRN
|
PARP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
XRCC1
|
PARP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
RAD50
|
PARP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP2
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
WRN
|
PARP2
|
â—¼ SHARES_COMPLEX
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
RAD50
|
PARP2
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21060331
21270334
21337561
21376743
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
XRCC1
|
PARP2
|
â—¼ SHARES_COMPLEX
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
PARP2
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
CRK
|
PIK3R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRK
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10962563
35044719
25241761
19380743
12878163
25814554
11418612
|
PIK3R1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10962563
35044719
25241761
19380743
12878163
25814554
11418612
|
XRCC1
|
PNKP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21637298
17353931
11163244
28821613
19155274
15367657
15385968
26496610
16713569
|
LIG1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
POLB
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
POLD4
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD4
|
POLD1
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD1
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD1
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
9286699
12403614
16510448
|
POLD1
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
12403614
16510448
|
POLD4
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
LIG1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
POLB
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
PCNA
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD3
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD3
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD2
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD3
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLB
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
LIG1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
PCNA
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD4
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD2
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24022480
9038370
16510448
|
XRCC1
|
POLK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
POLK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
PCNA
|
POLK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11900249
12466554
12648680
12930902
14624239
14657033
14726013
15189446
15189466
15459660
15703371
16697054
17035102
17116885
17296725
17582221
17652783
17884153
18087292
18157158
18196958
18584027
18677104
18809224
18931676
19217833
19225445
19258535
19622404
19686080
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22266823
22743550
23065650
23414611
24050180
8264637
8978692
|
RPA2
|
POLK
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
PCNA
|
POLK
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11900249
12466554
12648680
12930902
14624239
14657033
14726013
15189446
15189466
15459660
15703371
16697054
17035102
17116885
17296725
17582221
17652783
17884153
18087292
18157158
18196958
18584027
18677104
18809224
18931676
19217833
19225445
19258535
19622404
19686080
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22266823
22743550
23065650
23414611
24050180
8264637
8978692
|
XRCC1
|
POLK
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
XRCC6
|
POLL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
Reactome
|
16439204
17470781
22529269
15451442
14561766
12077346
10757784
9259561
16439205
11702069
18046455
9430729
12509254
|
XRCC5
|
POLL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
Reactome
|
16439204
17470781
22529269
15451442
14561766
12077346
10757784
9259561
16439205
11702069
18046455
9430729
12509254
|
PCNA
|
POLL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12368291
11784855
16174846
16189514
12081642
|
PYCARD
|
AIM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
19104081
23702978
26885855
27048821
27066895
27984721
|
PYCARD
|
AIM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
19104081
23702978
26885855
27048821
27066895
27984721
|
PYCARD
|
AIM2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
19104081
23702978
26885855
27048821
27066895
27984721
|
XRCC5
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC6
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
WRN
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
WRN
|
RAD50
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
RAD50
|
MRE11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19197236
16163361
10888888
8756642
17713585
|
WRN
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
PCNA
|
RFC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8999859
12400013
15225546
19285992
10353443
12192049
9649448
26496610
12045192
12171929
24958773
8861969
9092549
|
RFC5
|
RFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
9228079
9751713
28514442
9488738
8692848
33961781
24981860
22939629
26344197
|
RFC5
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
9228079
9751713
16189514
9488738
25416956
22939629
28514442
29892012
32296183
26264872
8692848
33961781
24981860
30021884
9092549
26344197
|
RPA3
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
LIG1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
POLB
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
RPA2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA1
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17145710
14499497
24126761
24332808
10373438
15735006
15965237
26474068
14734561
|
POLB
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
RPA2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
RPA2
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
PCNA
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
XRCC1
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
RPA3
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
LIG1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
POLB
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
TOP1
|
LIG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
14699148
13679147
|
MRE11
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
PCNA
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
56.0
|
1.0
|
ACSN
|
10858306
11283614
11585362
11756412
11948190
12202749
12637553
14624239
14726013
15385537
15703371
15871698
16216273
16442856
16449207
16697054
17055429
17116323
17426133
17599061
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19748837
19847258
20027199
20056333
20064462
20691907
20713526
20955519
21376743
21727086
2191300
21922195
22021614
22455312
22657828
22743550
22973052
23082994
23110144
23161013
23253856
23414611
23485469
24036544
24050180
24709898
9407949
|
WRN
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
WRN
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PCNA
|
WRN
|
â—¼ SHARES_COMPLEX
|
|
|
56.0
|
1.0
|
ACSN
|
10858306
11283614
11585362
11756412
11948190
12202749
12637553
14624239
14726013
15385537
15703371
15871698
16216273
16442856
16449207
16697054
17055429
17116323
17426133
17599061
17965729
18398454
18524993
18558713
18584027
18809224
19068479
19490890
1974050
19748837
19847258
20027199
20056333
20064462
20691907
20713526
20955519
21376743
21727086
2191300
21922195
22021614
22455312
22657828
22743550
22973052
23082994
23110144
23161013
23253856
23414611
23485469
24036544
24050180
24709898
9407949
|
WRN
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
WRN
|
XRCC1
|
â—¼ SHARES_COMPLEX
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
WRN
|
BMI1
|
â—¼ UP_REGULATES
|
✅
|
+
|
36.0
|
1.0
|
ACSN
|
11283614
12202749
12545156
15155580
15385537
16449207
17055429
17116323
17550342
17965729
18398454
18524993
18558713
18584027
18809224
19490890
20027199
20064462
20691907
20713526
20818389
21376743
21733352
2191300
21919891
22657828
22743550
23082994
23140366
23161013
23253856
23869868
24036544
24050180
24709898
9618481
|
PCNA
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
XRCC1
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PCNA
|
XRCC1
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
XRCC1
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
XRCC1
|
POLB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
15107487
26186194
8978692
16442856
15520167
11467963
26496610
15367657
25423885
16713569
|
XRCC5
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC5
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC6
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
XRCC6
|
MRE11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
PCNA
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
16442856
16697054
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
POLB
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
POLB
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9685411
12200445
19329425
8663274
11554294
|
POLB
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
PCNA
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
16442856
16697054
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
PCNA
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
PCNA
|
LIG1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
LIG1
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12171929
9649448
28073635
10559261
|
LIG1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
PLCG1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10072481
10781611
10811803
10925299
11169415
11476890
11532940
11994416
12040186
1281218
12845332
14585353
14764585
15214048
16488589
16919435
1712101
17397400
17496910
17517963
19568798
19909365
23523669
24584707
2536067
25456276
25572304
25960930
26552706
27216177
7682895
7890616
8226994
8649391
9535722
9846483
|
PLCG1
|
SRC
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10072481
10781611
10811803
10925299
11169415
11476890
11532940
11994416
12040186
1281218
12845332
14585353
14764585
15214048
16488589
16919435
1712101
17397400
17496910
17517963
19568798
19909365
23523669
24584707
2536067
25456276
25572304
25960930
26552706
27216177
7682895
7890616
8226994
8649391
9535722
9846483
|
SRC
|
PLCG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
8388373
16497976
16126727
16713569
17389395
1689310
20068231
17570479
16153436
16038803
1708307
7682059
7510703
18594017
12601080
8885868
8657103
17016520
|