Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 POLD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 BRCA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27899378
ATM YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MCPH1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16217032
E2F4 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 16135806
ATM PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12147700
NBN ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
MRE11 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
CHEK1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0706013104 17686975
BLM ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BRCA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
RPA1 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TOP3A ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
RPA3 ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP ATR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0706013104 17686975
ATR RMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR BRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATR BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
ATR SYCP3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19146767 11673449
ATR BRCA1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 23422745
ATR PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12147700
ATR RAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16436514
BLM ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TOP3A ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
BRCA1 ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
NBN ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
MRE11 ATRIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP BRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
ATRIP RMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791985 16327781
TP53 ATRIP â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
CHEK1 ATRIP â—¼   COLOCALIZATION 2.0 0.8 intact 20639859 8010047
ATRIP TOPBP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
BABAM1 BABAM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BLM PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16864798 0601828103
XRCC3 BLM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
RAD51C BLM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
ESR1 BLM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17268063
BRCC3 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19202061 0807485106
BRCA2 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19369211 0811159106
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
MCPH1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15220350
TP53 BRCA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003689107 20421506
SYCP3 BRCA2 â—¼   COLOCALIZATION 2.0 0.8 intact 22116401 8303438
MCPH1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19549900
PALB2 BRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19369211 0811159106
CDC45 CDKN2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15232106 5217098
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
E2F4 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12766778 18319725
CHEK1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20639859 8010047
E2F4 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
RPA2 CHEK1 â—¼   COLOCALIZATION 2.0 0.8 intact 20639859 8010047
E2F4 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 18319725
YWHAZ DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PARP1 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
E2F1 TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7734951
E2F1 MCPH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22136275
E2F1 CDC45 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10692433
E2F1 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24076372 18439978
E2F1 POLD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
E2F1 ACTG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15897325 18319725
E2F1 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F1 HSPA5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18840615
RAD54L EME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19017809 0807016105
XRCC3 EME1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
RAD51C EME1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
HUS1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MLH1 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 25502805 1004819
E2F4 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
TP53 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15781865
E2F4 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 18319725
XRCC3 MUS81 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
RAD51C MUS81 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PARP1 H1-2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18250087
PARP1 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18025084
PLK1 TP53BP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 1000287 20126263
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
E2F4 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15510213 18319725
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
TOP3A PML â—¼   COLOCALIZATION 2.0 0.8 intact 6743819 18418389
TP53 PMS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RPA1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17666013 9214288
TOPBP1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19652550
TP53 POLD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11375983
POLD1 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 10852724
E2F4 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15574595 18319725
RAD50 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAD50 MRE11 â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
RAD52 RAD51 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216387 12750383
RAD51B H2BC8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216790 14595808
TP53 RAD51B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9878257
RAD51C TOP3A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
RAD51C SLX4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
RAD51C RMI1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
XRCC2 RAD51D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10749867 5212428
E2F4 RAD54L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15782160 18319725
RAD9A CLSPN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20424596 7897378
MRE11 RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21052091 8081463
E2F4 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
XRCC3 RMI1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
CDC45 RPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC45 RPA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
CDC45 RPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10882098 10757793
XRCC3 SLX4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
SMARCA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20129940 8009769
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
SSBP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19066201
TOPBP1 TOP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17006541 5219150
E2F4 TOP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
XRCC3 TOP3A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
H1-2 TOPBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TOPBP1 PIAS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17006541 5219150
TOPBP1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17006541 5219150
TOPBP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18923429 7296625
TOPBP1 AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17006541 5219150
TOPBP1 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
EGR1 TOPBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16831524
TOPBP1 CDC45 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17887956
TP53 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
TP53 EGR1 â—¼   COLOCALIZATION 2.0 0.8 intact 5216887 14744935
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 BARD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14636569 15782130
KMT2B TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
TP73 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19815500 0905867106
E2F4 XRCC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 BARD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 BARD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067 18319725
E2F4 ACTG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 SMC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12789259 18319725
EGR1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12903198 18174897
UBC YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
NFYA HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22530004
SET YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
BLM RPA2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ATM RBBP8 â—¼   PHOSPHORYLATION ✅ - 0.8 0.8 Signor 10910365
CDC45 POLA1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RAD1 RAD17 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
RAD50 ATM â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 18854157
ATM RAD50 â—¼   PHOSPHORYLATION 0.8 0.8 Signor 17570479
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
GINS1 POLE â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 1204073 5215931 11244506
DDB1 MUS81 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 27354282 24412650
RAD51 MCPH1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19549900 20107607 32735676
CHEK1 RAD51 â—¼   PHOSPHORYLATION ✅ + 0.81 0.81 Signor 15665856
MDC1 UIMC1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
BLM PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 24239288
BRCA1 PMS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25184681 29656893
MDC1 BRCC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22990118 29656893
ESR1 MSH6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
MRE11 NBN â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
UIMC1 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 25252691
PIAS2 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19779455 34079125
PARP1 TOP2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 16794079
RAD51 XRCC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20189471 15065660 15123651 19327148
ESR1 SMC4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26166704 31527615
ATM CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 20068082
BLM RPA3 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
DDB1 HIST2H4A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST2H4A UBC â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
ATM MDC1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12607003
KMT2A UBC â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
RAD51B RAD51D â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ATM RAD17 â—¼   PHOSPHORYLATION 0.82 0.82 Signor 10608806
HIST2H4A KMT2A â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
EGR1 TP53 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
ATR ABL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10608806 20798688
ATRX NBN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24651726 27171262 23329831
ATRX RAD50 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24651726 23329831
NFYA BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11777930 16713569
PLK1 BRCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25483079 24067368 31730000 29656893
BRCA2 SEM1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 22293751 8384352
BARD1 MDC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12611903 29656893
RPA2 ESR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11953755 31527615
HIST2H4A TP53BP1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HIST2H4A SMARCA4 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
BRCA1 RBBP8 â—¼   UBIQUITINATION ✅ + 0.83 0.83 Signor 16818604
RBBP8 BRCA1 â—¼   RELOCALIZATION ✅ + 0.83 0.83 Signor 24832651
BRIP1 PMS2 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
PIAS2 TP53 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
AKT1 BRCA1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CHEK1 CLSPN â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RAD52 TP53BP1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ATRX MRE11 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24651726 27171262 23329831
BLM RAD50 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
MSH6 BLM â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10783165 15064730
PARP1 BRCA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 25252691 26831064
MDC1 RAD51 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28973861 16186822
NBN MLH1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17121922 10783165
CDC45 CLSPN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 23910567
ESR1 SET â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
RAD51 RAD51C â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
BARD1 BRCA2 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ATR RAD17 â—¼   PHOSPHORYLATION ✅ + 0.84 0.84 Signor 11687627
TP53BP1 UBC â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BARD1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
RAD50 BLM â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29523790 25084169 10783165
BLM TOP3A â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 20711169 8048867
FANCM RMI1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20064461 17289582 20347428 22392978
OTUD6A SSBP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
RPA1 RPA4 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MDC1 TOPBP1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
NBN BLM â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29523790 10783165
BRCA1 ABRAXAS1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 34591612
BRCA1 CLSPN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 15096610 22863316
CHEK1 DDB1 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
BLM MSH6 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
ATR TP53BP1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
TELO2 ATR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19097996 20427287 20801936 18160036 17384638
BRCA2 XRCC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 18212739 24141787 20450923 16621732
BRCC3 BARD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14636569 17664283 17525341
BARD1 MSH6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16391231 11498787
PALB2 RAD51 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26833090 22193777 20332121 28319063 22331464 20871616 24141787 33961781 19584259 28240985 23585894 20871615 29499138 25016020 28398198 16793542
CLSPN RAD9A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12766152 20424596
ESR1 UIMC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17311814 31527615
CDK8 MTBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30695077 29568061 26496610
ATRIP RPA1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDC45 TOPBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ATR TP53 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BABAM1 UIMC1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BLM CHEK1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BLM TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATM BRCA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRIP1 TOPBP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ABL1 ATM â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ATR BRCA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BRCA1 MLH1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HUS1 RAD17 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ABL1 RAD51 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
FANCM RAD52 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
E2F1 TOPBP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ATM MRE11 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10608806 10783165 15758953
ATM RAD17 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10608806 11418864 18344987
ATM TELO2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18160036 20801936 20427287
MRE11 BLM â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29523790 28506294 10783165
BRCA1 BLM â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25084169 10783165 26831064 29656893
BRCA1 RPA1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
BRCA2 BRCC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14636569 17664283
BRIP1 MLH1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
POLD2 POLD1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 31449058
RAD51 XRCC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15065660 17302439 11842113 28864920 9660962
BARD1 UIMC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19615732 17525341
ATM BLM â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ATR ATRIP â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 15451423
NBN RBBP8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
RAD51 RAD54L â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RAD51C XRCC2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
POLD1 RPA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RAD51B XRCC2 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BRCA1 ABL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17352427 12024016
MDC1 ATM â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29656893 14519663 28943310 12607005 26734725 18006705
ATR RAD17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20424596 10608806 11418864 14724280
ATR NBN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17526493 10608806 15758953 23368512
BRCA1 ATRIP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17616665 24073851 29656893
NBN BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10426999 18171670 19244116 12124328 10783165 25659039 25184681 25939603 11504724 29656893
MDC1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21622030 19766185 15569676 12611903 17525332 12607005 29656893
E2F4 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21102443 16713569 9244350
UIMC1 BRCC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18077395 19305427 21282113 19261749 19261746 23264621 19261748 19202061 17525341 20656689 19015238 19615732
MLH1 BRIP1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5220047 17581638
PARP1 E2F1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20133863 14627987
E2F1 MCPH1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23001041 18660752 23697381
SLX4 EME1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19596236 19596235 32398829 31495888 19595721
UIMC1 MDC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21622030 22990118 21857162 24240613 29656893
PMS2 MSH6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12799449 10748159 17148452
BARD1 RAD51 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14636569 32347575 28976962 25252691
ATRX RAD51 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HUS1 RHNO1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD1 RHNO1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD9A RHNO1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD51 TP53 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ATR TELO2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
BLM RAD52 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MDC1 RAD50 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
RAD17 RAD9A â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CDKN2A TP53 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ATM ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9168116 17409407 10212258 20798688 11375976 9168117
ABL1 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19783996
ABL1 ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20798688
RPA1 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
ATM BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11114888 11278964 29656893 10783165 11016625 10866324 10550055 15713674 18344987 10608806 17478428
ATM NBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24800743 10783165 25088203 11252893 30952868 10608806 17507690 22464731 25895060 10839545 15758953 10839544
ATM BLM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29523790 10783165 12034743
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
E2F1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22832221 23993922 12527885
ATM AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15546863 15899889
ATRIP ATR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19097996 28514442 19889979 17384638 15758953 14724280 15451423 23144622 26854234 21285353 18344416 20847938 20616048 15743907 14657349 11721054 15538388 17686975 18162465 17526493 33961781 15210935 18283122
ATR BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11114888 11278964 23901102 29656893 16713569 11016625 10608806 17478428
CHEK1 ATR â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15190204 10859164 11390642
ATR UIMC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18519686
TOPBP1 ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20068082 18769153
ATRX RAD51 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23801766 15466868 19671661 12205100 10851248 28976962 32876692 32457312 9321665 12750285 16990250
BRCA1 BACH1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17664283 15208681 16713569 19369211 17525340 15125843 15242590 16391231 25252691 11301010 11877378
RMI1 BLM â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20360068 20826342 23509288 24239288 26496610 15775963 20064461 20711169
BLM TOP3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12724401 20360068 11406610 23509288 24239288 10734115 26496610 30279242 11470874 15775963 10825162 20711169
BLM MLH1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12724401 10783165 11691925 11325959 21466675 11470874 19015241
BRIP1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21240188
PALB2 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19369211 25184681 19584259 23038782 29656893 26649820 30337689 28319063 28089683 28398198 22193777 19268590 22331464 34408138 23585894 25016020 19553677 24085845 25652403
ESR1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 1244506 11782371 15674350 29367421 27977889 17392432 16860316 10334989 16260778 11244506 16061635 12400015 17505062 20060929 25499220 16713569 31527615 11493692
RAD51 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31270457 31009828 11498787 16713569 19766185 25659039 19369211 25499220 9774970 28319063 17302439 9008167 14636569 28976962 24085845 34408138 29656893
MLH1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10783165 17148452 25184681 16786532 21240188 29656893
AKT1 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21242970 10542266 20085797 19074868
BRCA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11477095 17664283 16713569 21135251 19369211 9774970 25184681 14636569 24085845 34408138 25652403 14499622 29656893
BRCA1 MSH6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16260778 25184681 11498787 10783165
BRCA1 MRE11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10426999 10783165 17349954 25184681 23530059 16391231 11353843 24413181 11504724 29656893
BRCA1 BRCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19305427 17664283 19202061 22990118 25184681 14636569 25252691 29656893
BRCA1 UIMC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21622030 17525340 25184681 17525341 17643121 29656893 19305427 26446986 25252691 26027929 28569838 19766185 19261748 34408138 29499138 19615732 17525342 17621610 31932421 24085845
BRCA1 RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10426999 18171670 12124328 16713569 10783165 25084169 25184681 16260778 16391231 11504724 29656893
BRCA1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 9774970 9008167
PALB2 BRCA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20332121 19369211 24485656 17200672 24141787 19584259 28240985 23038782 16793542 26833090 26649820 28319063 24835992 30410870 17420451 28398198 22193777 19268590 21466675 22331464 19609323 26990772 23585894 25016020 19553677 28765325 33961781 20871615 22293751
PLK1 BRCA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32286328 14647413 24448238 24835992 28985013 12815053
BRCA2 BARD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14636569 17664283 16391231 19176389
CHEK1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18317453 24627786
RPA3 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 BRIP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
NFYA CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
DDB1 VPRBP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21957298 25499532 26613412 30166453 17314515 18606781 28416635 24558487 19295130 30590706 24412650 17609381 27571178 25532805 16949367 28202763 27354282 20870715 25557551 19287380 33355139 26344197
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
E2F4 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14576826 10208422
E2F1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18840615
E2F1 POLA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18347061 7929342
E2F4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15014447 11491305
E2F1 RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11313881
EME1 MUS81 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19596236 28514442 16189514 25224045 27354282 24733841 25319828 21962513 29738624 19017809 33961781 28575661 14617801 12686547 12721304 17289582 19363487 18413719
RAD9A HUS1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 14611806 14624239 14681455 11907025 12628935 32296183 9872989 10852904 19464297 10777662 10359610 11994305 11340080 15314187 26088138 33961781 26186194
RAD17 HUS1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 12578958 33961781 19535328 26186194 10884395 27387238
MDC1 RAD50 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30179224 29656893 14519663 12607005 12607003 18583988
MDC1 NBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15377652 30179224 12607003 18678890 29656893 27590578 25064736 20460517 19804756 23115235 14519663 15201865 12607005 20224574 18001824 18583988
MDC1 MRE11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30179224 29656893 20081839 14519663 12607005 12607003 18583988
TP73 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11309270 18829110 21245298
TP53 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 15781865
SLX4 MUS81 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25416956 29850896 25224045 21516116 23623386 22902628 25533185 32296183 23033263 19596235 31495888 23093618 21240275 19596236 23994477 29892012 32398829 24012755 19595721
NBN RPA3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
NBN RPA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
NBN MRE11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30179224 11238951 17612497 22941933 23530059 15758953 11062235 10426999 19244116 10783165 18458108 21884979 22464731 33558481 24413181 26455393 12447395 12679336 28369484 22078559 34038735 22231403 12419185 22939629 34348893 17526493 12861053 17500065 12750284 9705271 28363998 30440001 24981860 19270065 12607003 15734743
TOP1 PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 15247263 15848144
SLX4 PLK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25659891 19596235 31495888 25852190 32707033 22902628
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
PML TOPBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12919958 12773567
TP53 PMS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15781865
POLA1 POLE â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
E2F4 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15574595 18319725 16135806
POLD2 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16000169 10852724 16510448
RAD17 RAD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 12578958 33961781 19535328 11418864 10884395 27387238
RAD17 RAD9A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 20424596 14611806 12578958 11572977 25091155 19535328 10884395 27387238
RPA3 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 RBBP8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RBBP8 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17965729 21052091
RMI1 TOP3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 20360068 20826342 16537486 15775963 20064461 24509834 26186194 33961781 20711169
RPA1 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA1 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA2 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 BARD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
RPA3 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
TP53 POLD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
TP73 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16413471 21436470 18026135
TP63 POLD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
TP73 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11238924 19815500 10373484
TP73 POLD2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
ESR1 BARD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17275994
E2F4 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17531812 12789259 20946668
PPP1CC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14633703
ZBTB17 PIAS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25043018 14704274 22053792
SET MCPH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18718915 21515671 21911480
ATM RAD17 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MSH6 PMS2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
TOP1 TOP2B â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
PALB2 RAD51 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
ATR RPA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
RMI1 BLM â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711169 8048867
BLM RMI1 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 20711169 8048867
PALB2 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 8329239 22193777
PALB2 BRCA1 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 28319063
BRCA1 PALB2 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 8329239 22193777
RAD51C RAD51B â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 34591612
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
FANCM MUS81 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
POLA1 POLD3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
POLD2 POLD4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
MLH1 MSH6 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ATM TELO2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
MUS81 SLX4 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RPA3 RPA2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24126761
ATR CHEK1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 15775976
RPA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
FANCM RPA2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RAD51C XRCC3 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RAD51D XRCC2 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
BLM XRCC3 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
POLD3 POLD4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RAD51 RAD54B â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
BLM MUS81 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
RAD52 RPA2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
RAD51C RAD51D â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
UBC UBR5 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CDC45 GINS1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FANCM MSH6 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MSH6 MLH1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 12799449 30770470 10783165 10748159
BRCA1 PALB2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
BLM MLH1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BRCA2 PLK1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
ATR BLM â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RAD51 RPA1 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RAD51B RAD51C â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
PPP1CC YWHAZ â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
BLM TP53BP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
ABL1 RAD51 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 19427856 10212258 9461559 21653319
RPA1 RPA2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24207024 22939629 26399832 26496610 24981860 16514417 19214185 26344197
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
RAD9A TOPBP1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CHEK1 TP53BP1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
BLM RAD51 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19671661 29523790 12606585 17984114 11309417 11278509 19956565 18562274 15064730
BARD1 BRCA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12431996 17525341 29367421 27977889 19916563 12732733 10477523 20060929 23680151 8944023 22110403 12951069 23086937 14638690 27239795 29355525 9788437 11925436 11257228 24289923 14647430 19176389 15184379 9738006 16403807 29180510 11278247 33589814 15265711 15159397 34408138 16713569 19117993 20681793 16391231 11301010 16489000 23416467 17664283 15569676 29858377 19369211 18493658 29656893 20351172 28398198 12485996 32347575 19766185 14636569 10026184 12700228 31270457 11573085 11526114 24085845 25823446 33961781 32092106 18936166 28514442 20215511 25184681 26490435 28948225 12890688 12438698 28262780 26831064 9342365 10635334 15855157 11504724 11773071 25252691 9798686 26350354 21901007 24695549 12887909 17873885 11498787 27454289 11927591 24981860 25652403 25634209
PALB2 BRCA2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 19609323 7262167
BRCA2 RAD51 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9405383 19875419 23935068 14580352 9774970 15937124 11239456 21076401 10551859 16513631 21601571 25585578 12815053 16793542 11477095 26833090 21670257 26145171 18264088 15713648 9811893 12941707 25282148 20729832 26387543 24835992 18429819 15800651 17515903 21399666 18317453 22116401 11313963 33476590 14636569 15897881 15800615 10373512 9523196 9126738 27941124 17541404 12442171 9560268 20729859 12619154 16914443 28765325 17515904 31113933 28757209 15065660 19303847 28168276 19628690 12606939 24013206 24981860 20871615 15671039 22293751 21789034
HUS1 RAD1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 20847938 14624239 10359610 9872989 14681455 15122316 33961781 19464297 26186194 11944979 10777662 11340080
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
RAD50 NBN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30179224 12607003 12124328 11238951 17612497 22941933 23530059 24651726 15758953 11062235 10426999 10783165 22464731 19197236 12447395 12679336 26215093 22939629 34348893 17526493 17500065 9705271 16391231 30440001 24981860 26344197 15734743
RAD9A RAD1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 14611806 15314187 10359610 11572977 11340080 26088138 9872989 25091155 25602520 11907025 10852904 33961781 26186194 10777662 11994305 12628935
RAD52 RAD51 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28551686 10448035 8550550 10212258 9837724 20190268 17118963 9826763 12750383 10666456 15766559 19338310
RPA1 TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
FANCM RPA1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BABAM1 BRCC3 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
BRIP1 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5220047 17581638
RAD51 BRCA2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219969 17541404
BLM RPA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BRCA1 RBBP8 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BRCA1 BRIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BRCA2 PALB2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RAD52 RPA1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPA1 RPA3 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBC UIMC1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
PMS2 MLH1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15225546 20706999 18206974 16338176 11793469 20533529 18768816 10037723 12799449 12810663 26496610 20978114 12584560 16083711 30770470 11292842 17581638 11429708 22939629 19015241 25077178 10748159 25502805 33961781 14676842 22252508 17148452
RAD50 MRE11 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 30179224 12607003 30733337 10888888 23530059 24651726 11062235 17694070 10783165 31501894 33558481 19197236 24413181 26455393 10508516 16163361 28369484 26215093 34038735 8756642 22939629 34348893 17500065 12750284 9705271 16391231 27173435 28363998 24981860 19270065 11504724 26344197 15734743
BLM RAD51 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
RMI1 TOP3A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ARID1A SMARCA4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HUS1 RAD9A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RAD1 RAD9A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
POLD1 POLD4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TOPBP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
POLD2 POLD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPA1 RPA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
BARD1 BRCA1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
FANCM RMI1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATM ABL1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 17303408 22334513 11375976 11804596 23331499 21071413 16163361 17570479 18988627 9168116 23847781 9168117 20798688 15964794 19788416 9561848 22084676 12607003 10212258 15459660 11877377 15686624 17409407
BRCA1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12919958 12024016 17352427
ABL1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 23331499 26546517 9461559 15279774 15033353 19427856 11684015 19285032 20841568 15330855 15212693 10212258 12359302
ABL1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 23318434 10391235 21188172 25666857 20841568 11278685 23331499 27294865 25893286 21199784 17535448 21051857 10391250 18988627 10391249 28690977 25341038 19788416 26512706 10391251 20195489 12070014 15459660 20057499 15686624 21435002 11223036
ABL1 RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 23331499 11971963 21199784 21051857 12628935 12709442 21435002 20841568 15459660
ABL1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15448168 20841568
ABL1 RAD52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12379650 29590107 20841568 14757045 21804533
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
BRCA1 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MLH1 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9781043 16322221 16123081 11292842 10928988
ATM BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM MDC1 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
ATM ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
ATM RAD50 â—¼   PHYSICAL_INTERACTION 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
ATM MDC1 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM RAD50 â—¼   SHARES_COMPLEX 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM RPA2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM BRCA1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM CHEK1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDC1 â—¼   ENZYMATIC_REACTION ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
MLH1 ATM â—¼   UP_REGULATES ✅ + 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
MSH6 ATM â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
PMS2 ATM â—¼   UP_REGULATES ✅ + 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATM MDC1 â—¼   REGULATES ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM RAD50 â—¼   REGULATES ✅ 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
TELO2 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18160036
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
ATM TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24366874 20023394 18769144
ATM RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 29875999 15964794 11877377 17303408 9725899 16163361 14872059 23847781 9139719 10713094 9295339 20860841 16731533 12607003 22977173 7171818 15459660
ATM E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20972224 11459832 27679857 15494392 15140942 27028861 21543892 27025900 20860841 24741006 17570479 25101673 28812991 15838517 22174788
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM RAD17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11418864 14500819 27364693 17570479 10608806 17110331 11687627
ATM TOPBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11756551 18077418 19279141 17525332 17446169
ATM RPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17525332 11359916
ATM BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16199871 11146546 25766002 17984114 14643436 20719863 17363339 14729972 18054789 12034743 30496191 16880735 11375976
ATM RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11278446 26658951 17570479 22453082 12709442 18669648
ATM MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19709933 26240375 17570479 31353207 10608806
ATM RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 23468639 23675572 17570479 24837676 10910365 16249056 11689934 10608806 17525332 22743550
ATM CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 69.0 1.0 Omnipath 29774099 20976184 26683224 25663895 12676583 17303408 14657349 29167438 27545311 10859164 19056039 15485915 28808226 12588868 16163361 15650047 12676962 17570479 14988723 14681223 26516160 10608806 26069190 29741650 12676925 23847781 17118344 11252893 20376879 15964794 15149599 18691976 19059218 20068082 15707391 12607003 25450480 17525332 11553781 19646247 15870257 15459660 20798862 19716789 11877377 12660173 11390642 15674326 16782033 28396830 28228262 12446774 15533933 15212693 29555944
ATM BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 26927092 17303408 15159397 24746700 12024016 10866324 30197789 12919958 11114888 26745677 26383678 34301763 12427729 11313470 16163361 28035057 20068231 25939603 26320175 17570479 19683496 22743550 10608806 23802008 23847781 21203981 15964794 12183412 12607003 17525332 19996295 15459660 11278964 19651622 21706030 11877377 20952512 10373534 19622773 10550055 27170701 15212693 23704879
ATM ABRAXAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17525332 17525340 26778126
ATM SLX4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21655083 17525332
ATM RAD50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17570479 17081983 15302935
ATM MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28193847 21705321 22234877 12607003 12607005 22234878 17525332 18006705
RPA2 ATR â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR HUS1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR ATRIP â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RAD50 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15798197 16713580 16805667 17102137 17116885 17296725 17384638 17582221 18087292 18469862 18584027 18677104 18809224 18931676 18995830 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 22751496 23444773 24050180
ATR RAD1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR FANCM â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11877377 12086603 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15175241 15189446 15459660 15798197 16337602 16697054 16713580 16805667 17035102 17102137 17116885 17296725 17384638 17582221 18157158 18448394 18469862 18472307 18550849 18677104 18931676 18995830 19217833 19225445 19258535 19282663 19342888 19622404 19686080 19772495 19793801 19847258 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR RAD17 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC45 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR TOPBP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
ATR CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RAD1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR ATRIP â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR HUS1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RAD17 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR TOPBP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
ATR FANCM â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11877377 12086603 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15175241 15189446 15459660 15798197 16337602 16697054 16713580 16805667 17035102 17102137 17116885 17296725 17384638 17582221 18157158 18448394 18469862 18472307 18550849 18677104 18931676 18995830 19217833 19225445 19258535 19282663 19342888 19622404 19686080 19772495 19793801 19847258 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR RAD50 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11850621 11877377 12086603 12607003 14988723 15136767 15175241 15459660 15798197 16713580 16805667 17102137 17116885 17296725 17384638 17582221 18087292 18469862 18584027 18677104 18809224 18931676 18995830 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 22751496 23444773 24050180
MSH6 ATR â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
PMS2 ATR â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
MLH1 ATR â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATR CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR RAD17 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR RAD1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATR BRCA1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR PARP1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
ATR HUS1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA2 ATR â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC45 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
BLM ATR â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR HUS1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR FANCM â—¼   UP_REGULATES ✅ + 52.0 1.0 ACSN 11877377 12086603 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15175241 15189446 15459660 15798197 16337602 16697054 16713580 16805667 17035102 17102137 17116885 17296725 17384638 17582221 18157158 18448394 18469862 18472307 18550849 18677104 18931676 18995830 19217833 19225445 19258535 19282663 19342888 19622404 19686080 19772495 19793801 19847258 20051983 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
ATR RAD17 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATR RAD1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA2 ATR â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR CDC45 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATR RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TOPBP1 ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16530042 18769153 16285702 18066086
ATR BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 26927092 17478428 24746700 15159397 17531442 10866324 18677104 19622404 15798197 19793801 20860841 16713569 11114888 23422745 20936109 16322207 19282663 20068231 17116885 17582221 25879655 10608806 17384638 23346553 12773400 12183412 17525332 15459660 11278964 17296725 11877377 17102137 10550055 16522651
ATR CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18309293 24500207 19473886 12766152 18077418
ATR RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18677104 19622404 15798197 19793801 15485915 24842372 20051983 19282663 17116885 17582221 17384638 23273981 18511906 18716619 19490890 15459660 30135856 19357644 17296725 11877377 17102137 25956864
ATR RAD17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 11418864 26854234 19230642 14500819 25893301 16872911 21680713 16885023 33820915 24971543 10608806 11687627
ATR ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20616048 15451423 19889979 23144622 17686975 18344416
ATR E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 22184068 11459832 15494392 15140942 26843428 27028861 20413589 27025900 24741006 23202967 25101673 27903963 27827925 15838517 22174788
ATR RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 28666352 23684611 19440044 20860841 18289945 24819595 25520194 19843584 10608806 26057167 17035231 24906880 27908669 22977173 25249630 25070753 26271993 23319600 26212458 29875999 24965470 26474068
ATR NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17715134 15758953 17526493 18077418
ATR KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25841987 27308325 24148750 20818375 4709074 27220480
ATR CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 29774099 26683224 26658951 28180282 27545311 29605721 16461339 26165835 24971543 28937603 28573382 27713304 27643582 18723495 26082189 25205668 29088070 22971344 20536192 22353182 28051860 19276361 14681223 14988723 26069190 23892398 12676925 11252893 26643553 16520097 23383325 20396397 16431910 19059218 21440578 22357623 24753408 28572758 11090622 25795119 29309644 15870257 34398682 19716789 23508805 25965828 24947324 23380594 19071136 23118481 28396830 15533933 15190204 19737971 24023735 27283761 28025997 23696651 16360315 28915668 15707569 19062161 14657349 19489726 21937510 25448276 26721387 27558808 25104095 19056039 23468519 17081992 20679434 20062519 28808226 27679857 12588868 22203733 29928473 25459351 28558031 12766152 26748709 28986587 18265945 18669648 27775084 18691976 12781359 23583268 29221122 26633513 34509474 22564734 31928997 33863777 27685627 27167194 29118324 30796221 24366029 11390642 21907702 24632611 27068998 24349411 31591366 17686975 15665856 19781914 21736880 12676583 27690219 23386996 21482692 24113549 21730979 15775976 15272308 17851138 33811702 27271602 30510197 28273450 29209046 23849791 18794134 25024738 12676962 26438152 20932473 15279789 20376879 16414131 15149599 24387336 18790091 24327542 17525332 19646247 23997120 20798862 29022904 15674326 24500207 16137618 12446774 16885021 20639859 19101576 20976184 25663895 24244353 27603133 10859164 23333305 24621867 22863316 24072747 15650047 22084686 10859163 21851590 23613359 15629715 29741650 17118344 22706734 25565400 25301724 17327276 23006513 29242514 24906880 15707391 27908669 18353973 27708213 18243098 18603484 12660173 18955550 26039276 19473886 28255082 25898113 29163782 16629900 25937999 30100999 24140082 24970150 22084169
ATR XRCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23438602 26354865
ATR TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17145710 22778941 24395704 28468838 12401524 15159397 24877058 15254178 9733515 11483158 15806145 19056039 11875057 15865930 11551930 11883897 19923893 12548019 18697815 29170437 16293623 19010925 11709713 10446957 9363941 21748595 17272272 22797063 12242661 10196661 22084686 10747897 10608806 10673501 12091386 17118344 23892398 9765199 15489221 24037342 15140942 10435622 17241873 10597277 10801407 11711532 17174997 21593792 25201202 9843217 10606744 15024084 15226429 15922368 21415014 21480565 15585169 24947324 9925639 23380594 9733514 11865061 19625493 16390936 10951572 10570149 23311997 12111733 26144601
RPA1 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 ATRIP â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP TOPBP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
ATRIP RAD17 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP HUS1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP CLSPN â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP CDC45 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP RAD1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP RAD1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP RAD17 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP HUS1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP CLSPN â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP TOPBP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
PMS2 ATRIP â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
MSH6 ATRIP â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 12556884 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 18157157 18406444 18543256 19151707 19473888 19595721 19596235 19596236 19847258 20478261
MLH1 ATRIP â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 12556884 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17303408 17581638 18157157 18406444 18543256 19151707 19847258 20478261
ATRIP CLSPN â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10884395 11756412 11877377 12086603 12466554 12766152 12875843 14614141 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15242590 15375219 15377654 15459660 15485915 15703371 15743907 15798197 16530042 16697054 16713580 16805667 16818604 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 17855402 18157158 18451105 18469862 18543256 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP RAD17 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP RAD1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
ATRIP HUS1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 ATRIP â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP CDC45 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP RAD1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP RAD17 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
ATRIP HUS1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA3 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ATRIP CDC45 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 ATRIP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15743907 12791985 16407120 17339343
ATRIP BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24073851 17616665
BABAM1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19261748 19261749
MRE11 BLM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN BLM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 BLM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM RMI1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
BLM BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM FANCM â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM TOP3A â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM FANCM â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM RMI1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
BLM TOP3A â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12535671 12972610 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18550849 18931676 19217833 19270065 19282663 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BLM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20347428 20064461
RMI1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 15775963 23509288
CHEK1 BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21050475 20719863 25015292 25906194 15364958
BLM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12080066 11399766 22653443 24239288 15806145 11781842 16713569 15364958
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 BARD1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 BRCA2 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 E2F1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 BRCC3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 MRE11 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRCA1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 E2F1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
BRCA1 BRCC3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 BARD1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 BRCA2 â—¼   SHARES_COMPLEX 69.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337601 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18448394 18472307 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 19995904 20029420 20081207 20173781 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
BRCA1 E2F1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10884389 11877377 12496474 15175241 15220350 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 18660752 19525936 19793801 20029420 20376879 21060331 21337561 24254977 7575488 7935440
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
BRCA1 CHEK1 â—¼   REGULATES ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
E2F4 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20133863 21701264 17531812 17001309 20818429 17106239 23108140
E2F1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10660629 23285190 18660752 19466541 17106239 20068145 23108140
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
E2F4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9244350 18319725 16713569 12909625
UIMC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17525341 17525342 17525340 17621610
BARD1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 99.0 1.0 Omnipath 16403807 16391231 28262780 15159397 25652403 26350354 26490435 14647430 11927591 25184681 16713569 11526114 35203293 9738006 12732733 24289923 11573085 18936166 23086937 24085845 12890688 15855157 24695549 19369211 9798686 11257228 11498787 12700228 11925436 10477523 19176389 23680151 25634209 23416467 34726323 29355525 18369654 14636569 11504724 12951069 19117993 20060929 17873885 14638690 18493658 11278247 15184379 22110403 11301010 11773071 12431996 10635334 20029420 9788437 17664283 21901007 25252691 12485996 10026184 12438698 17525341 16489000 8944023 15265711 12419249 20681793 9342365 27239795 20215511 25823446 19916563
ABRAXAS1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17643122 19261749 22357538 17525340 19261746 21282113 19261748 25184681 17643121 19305427 23416467
E2F1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9244350 18660752 18319725 11278247 12697828 16713569 12909625
AKT1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17428466 20832017 20085797 21242970 17570479 10542266
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
BRIP1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 22032289 21240188 34591612 18285836 16713569 14576432 17596542 17525342 17525340 15242590 25184681 19369211 18369654 28911102 17581638 15125843 11301010 15133502 19452558 27399284 18717574 17525341 22792074 14576433 20173781 11877378 20681793 14578343
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
BRCA1 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 21908405 18285836 16713569 15485915 25310973 9738006 17525342 17525340 16843262 24085845 25184681 26387952 18369654 9811458 16818604 20351172 23416467 19442256 10196224 10910365 19452558 11739404 25252691 10764811 25659039 17965729 11689934
BRCA1 PALB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26649820 19268590 28089683 28319063 19369211
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
BRCA2 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA2 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 BARD1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA2 XRCC3 â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15496928 15549137 15590677 15650050 15655342 16337602 16697054 17349954 18001825 18171670 18212739 18660752 18931676 19217833 19270065 19473888 19490890 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20021983 20029420 20064462 20081207 20376879 20723763 20813759 21060331 21337561 22266823 22505525 22751496 22771115 23444773
BRCA2 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA2 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA2 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 BARD1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA2 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA2 XRCC3 â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15496928 15549137 15590677 15650050 15655342 16337602 16697054 17349954 18001825 18171670 18212739 18660752 18931676 19217833 19270065 19473888 19490890 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20021983 20029420 20064462 20081207 20376879 20723763 20813759 21060331 21337561 22266823 22505525 22751496 22771115 23444773
TP53 BRCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9619832 11295099 18765668 12591928
PALB2 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17420451 16793542 26990772 19268590 22293751 17488615 19369211 23585894 24485656 20332121 24141787 26649820 19553677 17200672 26833090 23038782 17200668 15115758 19609323 30410870 19584259 22193777
PLK1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 32286328 12815053
SEM1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 26833090 26145171 22293751 24013206 10373512 16205630 16239144 17563742 12228710
BRCA2 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 87.0 1.0 Omnipath 17145710 21601571 15937124 17541404 11313963 16914443 26145171 21670257 18264088 19303847 25585578 12815053 16793542 21789034 25282148 17515904 9126738 20729859 15703751 21076401 15065660 22293751 19875419 12606939 22116401 12619154 23935068 15800615 33476590 15800651 15671039 11477095 16513631 9811893 10551859 20729832 9523196 14636569 17515903 12442171 9405383 26833090 21399666 19628690 9560268 10373512 14580352
BARD1 BRCC3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCC3 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BARD1 BRCC3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCC3 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCC3 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
TOP3A BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RBBP8 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD50 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 BRIP1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BRIP1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOPBP1 BRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20159562 25374583
RPA1 BRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17596542 19419957
TP53 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16103197 22467867 18555006 8631601 11402335 19649205 22020338 21164364 17265068 16764954 15775976 22056554 18275833 21483786 10348346 19216023 12384561 12091906 19901969 11360201 15205322 11818069 21892281 10980602 11739748 11559812 24672805 10097151 17907153 19244234 15361884 10652576 9436028 21447739 20569441 21555589 21637567 10816133 9774662 19240179
TP73 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12766778 18555006 11870517 18829110 11309270 14733783
E2F1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11314038 12766778 20664976 10914734 16211008 10594030 11062467 11705881 11526499 15716352 19641316 21765927 22621932 19115249 11870517 12695664 20580656 15175242 17912037
TP63 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9151818 19340300 19554267 21093383 19672307 8995628
E2F1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11314038 16135794 11883935 12446760 18319725 15175242 11034215
CDKN2A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15856024 15989956 9724636 19960022 12740913 17158541 12640129 19590512
HUS1 CHEK1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RAD1 CHEK1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
TOPBP1 CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RAD17 CHEK1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 CDC45 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
HUS1 CHEK1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RAD1 CHEK1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD17 CHEK1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
TOPBP1 CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
HUS1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
TOPBP1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
RAD17 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
E2F1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10884389 12496474 15220350 15279786 17218262 17303408 17660363 18590585 18660752 19525936 20376879 7575488
CHEK1 RPA2 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 CDC45 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RAD17 CHEK1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 CHEK1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 CHEK1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA3 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 CDC45 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA2 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 RPA1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
AKT1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 20832017 18691976 23108403 17418864 20068231 12062056 15107605 17570479 19664995 18669648 26091525
E2F1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7575488 18590585 20376879 17303408 18660752 19525936 17660363 15220350 15279786
CHEK1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 26610585 27685627 18285803 22730303 18317453 22705496 29977027 19473886 22665067 25852742 25909291 24847116 24204313 15665856 24238855
CHEK1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22084676 18524021 23508805 14585975
CHEK1 CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 18451105 15707391 16123041 21680713 22655267 12766152 16963448
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
POLD2 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA3 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA1 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD3 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
POLD1 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
DDB1 POLD4 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
E2F1 RAD51 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15279786 17218262 17303408 17660363 18590585 7575488
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
E2F1 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16398215 23285190 17218262 12629508
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
E2F1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12766778 11101847 11988839 14602923 18660752 19188449 18029729 18521084 15210709 11115495 17980704 19363520 12789260 21310950 22952705
PARP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14627987 20133863
TOPBP1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 20413589 18660752 14576433 17006541 12697828 14576432
CDK8 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20616879 18794899 22945643
MCPH1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23697381 18660752 23001041
E2F1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15210709 11988839 17488475 11937641
E2F1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15766563 22699938 17218262
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
EME1 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
FANCM TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
PLK1 FANCM â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
FANCM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
PLK1 FANCM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18931676 19270156 19622404 19680264 19686080
RAD17 HUS1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RAD1 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
HUS1 RPA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RAD17 HUS1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RAD1 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 15871698 16216273 16697054 16713580 16731526 16805667 16879101 16885023 17102137 17116885 17129768 17296725 17303408 17384638 17395641 17426133 17493829 17582221 17855402 18469862 18543256 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 23507534 8943031 9524127
CLSPN HUS1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA3 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 CDC45 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA2 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
HUS1 RPA1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN HUS1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD50 MDC1 â—¼   PHYSICAL_INTERACTION 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
MDC1 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RAD50 MDC1 â—¼   SHARES_COMPLEX 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
MLH1 PMS2 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10882712 11900249 12556884 12648680 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17036055 17303408 17581638 17884153 18157157 18406444 18543256 18931676 19151707 19473888 19595721 19596235 19596236 19622404 19686080 19805513 19809470 19847258 20173781 20478261 21376743 22101340 22257761 22373527 22743550 22824526 23085398 24050180
MLH1 PMS2 â—¼   PROTEIN_INTERACTION 40.0 1.0 ACSN 10882712 11900249 12556884 12648680 12947387 15136767 15703371 16332722 16612326 16697054 16713580 16858402 17036055 17303408 17581638 17884153 18157157 18406444 18543256 18931676 19151707 19473888 19595721 19596235 19596236 19622404 19686080 19805513 19809470 19847258 20173781 20478261 21376743 22101340 22257761 22373527 22743550 22824526 23085398 24050180
MLH1 PMS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 25077178 17145710 10748159 17148452 11429708 18206974 19015241 16338176 20706999 15225546 25502805 19022408 12584560 26496610 14676842 16083711 11793469 10037723 11292842 22252508 17581638 12799449 18768816 20533529 31515488 20978114 12810663
RAD54L MUS81 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19017809
NBN UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
NBN BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
NBN ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
NBN PARP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
MRE11 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 22464731 26455393 12861053 17500065 15734743 12419185 19270065 22078559 19244116 21884979 12679336 11238951 12607003 9705271 17713585 10783165 12447395 10426999 18458108 15758953
RAD51B PALB2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 19268590 17996710 19369211 17996711 20871616 20871615 28089683 12912992
XRCC2 PALB2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 19268590 17996710 19369211 17996711 20871616 20871615 28089683 12912992
RAD51D PALB2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 19268590 17996710 19369211 17996711 20871616 20871615 28089683 12912992
PALB2 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19423707 20871616 24141787
PARP1 RBBP8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 25642960 25789972 11440997 25643323 20483915 25642963 15135726 16012167 11340072
PARP1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 20875401 15911331 15848144 14699148 15247263
PARP1 POLA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9563011 9518481
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
E2F4 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17531812 15105433 17981789
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18418051 23948487 18174154 22084676
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
PLK1 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15845385 28512243
PLK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20126263 25607646 24703952
PLK1 CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 16885022 16934469 15163406 16885021
PMS2 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18768816
POLA1 POLD4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLA1 POLD2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLA1 POLD1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 8104944 1682322 1671046 9191022 1974050 10751307 7713898 7378348
POLA1 POLD1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLA1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLA1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLA1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD4 POLD1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 POLD1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD1 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD1 POLD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
E2F4 POLD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 11799067
POLD1 POLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 9286699 12403614 16510448
POLD1 POLD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12403614 16510448
POLD4 POLD3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 POLD3 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD3 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD2 POLD3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD3 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
POLD4 POLD2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD4 POLD2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11756412 14624239 14726013 15703371 16697054 1974050 19847258 22021614 23414611 27760120 27760777
POLD2 POLD4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 1671046 8104944 8144677 9081985 1974050 1328683
RAD17 RAD1 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RAD17 RAD1 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA2 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 CDC45 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA1 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD1 RPA3 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD1 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD17 â—¼   PHYSICAL_INTERACTION 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA3 RAD17 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 RAD17 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RAD17 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RAD17 TOPBP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
CLSPN RAD17 â—¼   SHARES_COMPLEX 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RAD17 TOPBP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
CLSPN RAD17 â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA2 RAD17 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 RAD17 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 RAD17 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RAD17 CDC45 â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 10884395 12086603 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16885023 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
CLSPN RAD17 â—¼   UP_REGULATES ✅ 38.0 1.0 ACSN 10884395 11877377 12086603 12766152 14726013 14988723 15136767 15175241 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17493829 17582221 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19847258 20051983 20478261 8943031 9524127
RPA1 RAD17 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RAD17 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 RAD17 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RAD17 RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16189514 12578958 18082599 10884395
ABRAXAS1 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
TOP3A RAD50 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD50 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD50 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
RAD50 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RAD50 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19197236 16163361 10888888 8756642 17713585
SEM1 RAD51 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 24076221 22593209 14527420 23509288 24509834 18957201
RAD51 BARD1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 BARD1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
TP53 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513613 16322760 20802511 16398215 18769160
E2F4 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11799066 20133863 21701264 17531812 17001309
XRCC3 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9660962 23438602 28864920 11842113
TP53 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 8617246 11002423 16713569 16322760 16983346 9380510
RAD52 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15766559 17145710 9826763 20190268 17118963 10666456 12750383 9837724 19338310 10448035 10212258
RPA2 RAD52 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11571269 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17582221 17884153 18677104 19473888 19772495 19793801 19809470 19847258 20081207
BARD1 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
XRCC3 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD52 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RPA2 RAD52 â—¼   PROTEIN_INTERACTION 18.0 1.0 ACSN 11571269 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17582221 17884153 18677104 19473888 19772495 19793801 19809470 19847258 20081207
XRCC3 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD52 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RPA3 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RPA2 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
RPA1 RAD9A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14500360 8943031 14624239 12578958 14605214 10777662
TOPBP1 RAD9A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20724438 11395493 12941802 17006541 22925454 19652550 17575048
TOP3A RBBP8 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
RBBP8 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BARD1 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOP3A RMI1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
MRE11 RMI1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOP3A RMI1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 15496928 15549137 15655342 16537486 16595695 16697054 18001825 18171670 18212739 18931676 19217833 19270065 19490890 19622404 19686080 19772495 19847258 19945966 20021983 20064462 20826342 22266823 22657828 23253856 24089143 24095737
RPA3 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDC45 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDC45 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 RPA1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CDC45 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA1 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 TOPBP1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA1 TOPBP1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC45 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 TOPBP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 RPA3 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC45 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 CDC45 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 RPA3 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA2 TOPBP1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 TOPBP1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 TOPBP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CDC45 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CLSPN â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CDC45 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 CDC45 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 11900249 12648680 14624239 15459660 15703371 16697054 17102137 17116885 17296725 17582221 17884153 18677104 19793801 19809470 19847258
RPA3 TOPBP1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 CLSPN â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA3 TOPBP1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
E2F4 RPA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 11799066
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
MRE11 TOP3A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
TOP3A BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
CLSPN TOPBP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
CLSPN TOPBP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
E2F4 TOPBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17531812 15195143
AKT1 TOPBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24081328 17913746 33556369 17006541
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
EGR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9242687 17822668 15958557 12755686 16990849
TP53 NFYA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9249061 12403781 21683812 12167641 18372207
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
EGR1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15225550 14744935 11251186 16713569 12384981
PPP1CC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 17274640 15178317 16501611
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
TP53 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11238924 18431400 21508668 9891077
TP53 NFYA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17145710 16959611 15831478
TP53BP1 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
TP53BP1 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
TP53BP1 UIMC1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
TP53BP1 BARD1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
EGR1 TP73 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17822668 16990849 10574463
MRE11 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
BARD1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BARD1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BARD1 XRCC3 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
XRCC3 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 XRCC3 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
XRCC3 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 XRCC2 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 XRCC2 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
MRE11 BARD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
MRE11 ABRAXAS1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
E2F4 CLSPN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18319725 16135806 17251008
CLSPN CDC45 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC45 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CLSPN CDC45 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AKT1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11756412 9705322 11923280 16697215 20398329 18372248 12865427 15071501 15808505 20138985 20214616 15883165 15169778 10949026 12861023 11715018 18636226 9812896 17680028 11956222 10722653 20832730 18570873 16376338 17052453
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 PDCD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17053147 17081983 18296647 18187866 17287340 16357133 16964243 18669648
KMT2D ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16603732