Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SUMO1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
SUMO2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
KAT5 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
SUMO1 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12393906 20972456
MDM2 MDM4 â—¼   COLOCALIZATION 2.0 0.8 intact 17159902 5219425
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
SUMO1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12393906 11384992
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
SUMO1 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17036045 5219211
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF6 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
RYBP UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PTEN YAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PTEN RYBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
DNMT1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339266 21229291
EZH2 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24719098 22956625
BMI1 PTEN â—¼   COLOCALIZATION 2.0 0.8 intact 19903340 8291464
PTEN BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19903340
CBX4 BMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17332741 5219708
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
EZH2 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21465172 19351856
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
TRAF3 BIRC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18997792 18997794
PJA1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28067271 23688634
RYBP LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YAF2 RING1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
TRAF4 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MDM4 UBB â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
ERCC6 UBP7 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31775559 22032989 26030138
SUMO1 CBX4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20098713 33961781 22467880 24654937
PTEN WWP2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21532586 22427670 30016585 30849479 27295432 24063548 27852060 31592114 28475870 15717329 33039560
SUMO2 UBP7 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19471022 26950370 33006472 32786267 25027693 21252943
SUMO2 CBX4 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19471022 15175327 20098713 21252943 21693764
P53 LMNA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 30419336 25144556 29568061
SIR7 UBP7 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32711345 28655758 22586326
TRAF2 TRAF3 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ERCC6 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
KAT5 UHRF1 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
MDM2 CUL4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34026424
CUL4B UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 28225217
ERCC3 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
EZH2 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
IFIX HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
KAT5 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25865756 21045206 32440780 23775119
KAT5 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27295567 16169070
YAF2 MDM2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MYC MAGD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC UBP11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC DNMT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC PHLB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC RING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
PML EZH2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17560333 27634302
IFIX PPM1G â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
BIRC3 SUMO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30948266 21988832
UBP7 SUMO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22875967 24654937
SUMO1 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12177000 21242980
UBAC1 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 22939629
YAF2 UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
UBB UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12507430 27452404
UBB P53 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17936559 23443559
PCGF6 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 12167161
PCGF1 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26687479
BMI1 LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26468281 34316702
KIF23 PHLB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
KIF23 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
UBP7 CHFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17442268 19182791
ESR1 BCOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26487511 31527615
PCGF1 PCGF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22493164 24981860
BIRC3 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23524849 30948266
CBX4 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20601937 33849069
PCGF6 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RING2 ANDR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33640491 24457600
CSN5 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 31950832
TCF25 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TULP3 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SEN15 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SUH UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
IFIX UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
CCD41 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZBT44 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
IF16 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
GA2L1 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
KHDR2 UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LCOR UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
POTEC UBP7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
UBP7 MAGD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30367141 22863883
UBP7 WWP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16713569 25071155
IF16 TRIPC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25693804 25665578
CCD41 POTEC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DHX40 PPIL4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
UBAC1 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
MYC ERCC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33381997 17314511 29467282
MYC PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 30415952 29467282
MYC LMNA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
TULP3 PML â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33187986 33961781
PML SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 15356634
ATX1 SUMO1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24882209 21308649 15824120
TRAF6 BIRC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20097753 24464131 23524849 29545793
UBP7 WDR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26496610 32601462
TCAL1 UHRF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19615732 26186194 33961781
P53 SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12732139 23687300 24157709
CBX4 PCGF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 27505670
CBX4 BCOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 27505670
ANDR BCOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28611094 31925334 33640491
PHF7 TCAL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PHF7 UBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
YAF2 RYBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
RYBP UBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22325352 33961781 26186194
RING2 SCML2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26496610 22325352 31043422 24457600 25605328
MAGL2 UBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28973533 34265304 23452853
F170A UBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ARHG6 UBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32203420 33961781
AR6P4 UBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
YAF2 UBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22325352 33961781 27684187
UBP7 MARH7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27302477 16713569 18410486 23105109
UBP7 UHRF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23105109 27114453 27129234
KAT5 MDM2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
UBP7 PML â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 26496610 21305000 20719947
ESR1 SUMO1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 15961505
TRAF2 TRAF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9718306 30561431 15383523 21903422
TRAF3 BIRC3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20097753 33608556 23524849 23612708
ESR1 UBP7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23403292 31518603 31527615
ESR1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
ATX1 SUMO2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24882209 25959826
UBP7 LMNA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 25925205 29568061
ANDR UBP7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33640491 26175158 34585037
PJA1 UBP7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22626734 33961781 28514442
BIRC3 TRAF6 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
UBP7 MYC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30415952 29467282 27618649
AXIN1 SUMO1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22509369 18632848 26871637
TRAF6 TRAF4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25241761 16052631
ATX1 TRAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32814053 25416956 32296183 16713569
TRAF5 TRAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9718306 32296183 21903422
MCMBP MCM4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24299456
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
ANDR EZH2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24457600 27728805 30628724
RING1 PCGF1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
P53 F175B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 25283148 33961781 26186194 32807901
TRI27 MAGL2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23452853 28973533 20864041
MDM2 UBB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MYC HUWE1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17314511 16269333 26279298 18488021 29467282 31677785
UHRF1 KAT5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19800870 23677994 21045206 29268763
UBP7 CCDC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19615732 25885523
AXIN1 UBP7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29045831 31519875 17510365
RELB UBP7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 32587091
UBP7 ACD â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 16713569
MAGB2 UBP7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 33961781
UBP7 PHLB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26496610 21988832
UBP7 ATX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 12093161
UBP7 PKHO1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 16713569
DAXX DNMT1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
HUWE1 P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31570706 22552282 15989956
P53 KAT5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18485870 18280244 16601686 23677994 17189186 33849647 15310756 17704809
SUMO1 MDM2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21316347 12917636 22411991 18583933 15876874 12393906 12297306 20972456 11384992 15876864 17000718
TRIPC MYC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20208519 29467282
MYC MCM4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
SUMO2 PML â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17000644 16189514 23543742 28851805 19553342 21148299 22155184 24190887 20826694 21779164 22578841 17081986 21693764 24637324 15940266 20797634 9452416 19471022 16713569 25027693 21252943
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
TRAF6 TRAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 25416956 21988832 33961781 21516116 27107012
UBAC1 UBB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
TRAF1 UBB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 14743216 33961781
PTEN P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12620407 16713569 18339852 24141722 14559824
LCOR EZH2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 27705803
PCGF1 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27505670 27705803 22325352 33961781 24981860
PCGF1 UBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26687479 27705803 26496610 22325352 33961781
CBX4 PCGF6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21282530 33961781 27705803
RING1 UBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20800574 20601937 33849069 26496610
PCGF6 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
YAF2 BCOR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26687479 27505670 26496610 27705803 22325352 33961781 24981860
LAP2A UBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30804394 28902428 16713569 26496610
TCAL4 UBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30804394 30367141 19615732 26496610
TCAL1 UBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19615732 26186194 33961781
UBP7 TRI27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24144979 29688809 23105109 26496610
UBP7 PPIL4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30804394 30367141 19615732 26496610
UBP7 F175B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19615732 25283148
UBP7 FBX38 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30804394 30367141 19615732 26496610
UBP7 DHX40 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30804394 30367141 26496610 33961781 34079125
UBP7 TRIPC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30804394 30367141 19615732 27800609
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
TRAF3 TRAF5 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
UBP7 HUWE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25147182 19615732 26496610 27934968
ATX1 KAT5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17110330 32814053
TRAF6 TRAF5 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8153045 21516116
TRAF2 TRAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32296183 16189514 16260598 21782231 16713569 25416956 9500555 33961781 21516116 21903422
TRAF5 TRAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 22493164 25416956 29176576 33539883 21516116 27107012
UBP7 TRAF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11279055 31666375 16713569
SMAD3 UBP7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34580281 18729074 21988832
P53 AXIN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23826318 19731416 21057547
UBP7 MCM4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19615732 26950370
UBP11 RELB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 27609421
BMI1 UBP7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20800574 20601937 25605328
UBP7 TRAF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11279055 31666375 16713569
UBP7 TRAF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11279055 31666375 16713569
UBP7 EZH2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32064169 31130994 33849069 32453339 27634302 20800574 31866294
PCGF1 RYBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16943429 28514442 26687479 27505670 27705803 22325352 33961781 24981860 26186194
BCOR RING1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16943429 26687479 27505670 27705803 26496610 24981860
RING1 P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29187402 22907436
RYBP P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19098711 34316702
UBP11 P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25471832 19615732 34141823 33567341
UHRF2 P53 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21952639 22902639
UBP7 TRAF5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11279055 31666375 16713569
UBP7 TSYL5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21170034 29748603
TCAL4 UBP11 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19615732 26496610
HUWE1 UBB â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BCOR RING1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DAXX MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PTEN WWP2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PCGF1 RYBP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BCOR RYBP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CSN5 CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34026424 31973889 23238014 18850735 23357576 26496610 33961781 26186194 19615732 21145461 19295130 30945288
CUL4B EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23238014 24292684 27634302
P53 ERCC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 7663514 12379483 8612585 32807901
KAT5 ANDR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10364196 11994312 11591700 16713569
KAT5 MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12776177 15572685 18003922 35140242 30415952 20946988
MDM2 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6799761 18566590
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
MDM4 UBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20713061 18566590 15916963 31519875
MYC PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17146439 15735755 21150319 32592588 30415952
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
UBP7 PPM1G â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30804394 27880917 30367141 22361354 19615732
SUMO1 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15144954 23543742 22214662 23604351 15017387 12917636 16732283 18583933 11867732 10961991 10562557 17369817 20972456 19246003 19684601 23825024 10788439 15242646 23150668 15327968 15576338 16122737 17060459 21316347 16713569 15931224 20861261 23772552 32807901 20534433
UBP7 TRAF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11279055 16713569 31666375 18952891 20622874
UBP7 UHRF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23297342 26299963 34094715 26496610 21268065 22411829 26046769 28803780 21745816 32884836 24013172
PTEN UBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29117568 24270891 31685992 18716620 24063548 26280536
SUMO2 DAXX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17081986 19471022 19394292 32786267 16475184 28851805 21252943 22578841 21693764 21383010
DAXX UBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23536002 32587091 18566590 16845383 33961781 24981860 23348568 32545337
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
BMI1 YAF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 24457600
TRAF3 TRAF5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 25241761 9718306 15383523 21903422
DNMT1 EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31130994 16357870 22094255 28068325 21378168
P53 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 26556313 10766163 17545634 21761334
YAF2 RING1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 27705803 22325352 33961781 24981860 21516116 27684187
RING1 PCGF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 22493164 12167161 27705803 22325352 33961781 24981860
PCGF6 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 24981860 26186194
UBP7 BCOR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26687479 33722704 16713569 26496610
BCOR RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16943429 28514442 26687479 27505670 34316702 27705803 22325352 33961781 24981860 26186194
NOTC1 UBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23022380 30370059 30224337
UBP11 UBP7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30804394 33567341 30367141 20601937 26496610 22411829 19615732
UBP7 RN169 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30773093 28325877 26496610
UBP7 MCMBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19615732 24190967
UBP7 TRAF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31666375 11279055 23388826 16713569
UBP7 SCML2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26950370 26496610 31043422 19615732 25605328
UBP7 RN220 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19615732 25266658 16713569
TCAL1 UBP11 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17353931 26496610 33961781 26186194 19615732
DAXX SUMO2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ERCC6 CUL4B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
P53 ERCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22032989 16713569 10882116 7663514
ESR1 KAT5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 17418098 16260778 22081016 11591700
KAT5 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18499675 11927554 18264029 19150978
MDM2 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11927554 16904321
MDM4 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 32300648 25512388 21988832 25384516 25809483 17616658 25105592 12874296 31796886 29295817 32075226 20705607 17301054 22493164 25703327 27777309 29523541 27617579 23028042 20473904 22120712 22333590 22902369 22745160 12860999 19432880 21925390 28205554 25659040 19838211 33985974 16055726 25961923 32427989 18566590 22266850 18219319 29057323 10608892 30598450 29524278 25825738 17159902 24813712 31024344 27621617 15604276 29262653 19619542 10218570 28628118 16227609 10827196 12393902 24755078 20724842 34551723 27215386 11606419 20484049 12370303 23671280 26001071 26720344 33961781 12483531 23946421 19683495 26359458
MDM2 UBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28406480 16474402 26238070 16943424 28196907 29295817 22056774 34799561 26971997 24462112 18566590 29236775 16402859 20713061 31647545 20816748 16845383 17380154 26460617 27452404 17936559 15916963
MDM2 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22869143 16713569 12915590 23169665 14507915 19150978 20972456 15195100 12759344
MDM4 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10629057 29023092 30672125 31152661 17110929 19521340 10075736 30832340 22807444 12874296 25609649 11528400 24445145 17080083 18677113 20705607 27249653 9226370 17301054 18485870 26148237 27114532 16024788 22374672 24127580 18316739 26876197 29523541 21088494 23028042 24667498 30045945 20515689 25464845 22745160 19432880 21925390 28205554 20174603 21965653 25961923 21075307 22266850 8895579 28487147 32511789 10608892 30598450 25825738 19305137 19255450 11223036 15604276 16713569 28628118 16227609 10827196 12393902 20724842 24659749 12370303 23671280 17875722 33961781 31462704 26186194 23946421 31066983 19075013 15916963 19153082
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
AXIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19131971 20399964
P53 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 22869143 16713569 12915590 14976551 16007146 20972456 12006491 15375079 11025664 11704853 11080164 21057547
SUMO1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11948183 16189514 9885291 19015637 21305000 23028697 28851805 23604351 15017387 22155184 21057547 19380586 24190887 20826694 20972456 23830076 17027752 24654937 25497731 9756909 21779164 31879127 17081986 18625722 8806687 17081985 17344210 19217413 17036045 18474224 9452416 20188669 16501610 22406621 22875967 9427741 15561718 21098080 11080164 11160742
ESR1 SUMO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15961505 24119295 18404132
SUMO1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18093978
UHRF1 DNMT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20613874 22064703 19798101 33170271 17673620 29691401 19800870 21045206 29268763 33465813 21268065 21745816 24782312 27045799 19943104 17934516 28803780 31322780 27049577 26065575 24368767
TRAF1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10544141 25241761 20385093 14557256 21903422 14743216 32296183 29748372 11181075 15383523 8702708 8069916 19287455 16713569 9718306 25996949 9500555 33961781
SMAD3 WWP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18729074 25910212 23938591 21516116 21258410
SMAD3 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11707452 11280774 12226080 16713569
MCMBP MCM4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17296731 24299456 22540012 25036637
ANDR DAXX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15572661 27671201 32694250 15350595
CBX4 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 22078878 9199346 34316702 18453536 20601937 19636380 26496610 27705803 22325352 27647897 33961781 24981860 17332741 24457600 12829790
RING1 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9858531 25416956 29402932 19451220 32296183 22493164 22897849 15386022 16751658 20601937 19636380 16359901 34316702 24457600 9199346 27705803 34133714 22325352 33961781 24981860
BIRC3 TRAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11907583 25241761 16713569 30948266 9384571 25996949 33961781 23524849
UBP7 DNMT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30804394 21045206 30367141 31130994 26496610 25753001 21268065 22411829 32884836 21745816 25960197 19615732
BCOR PCGF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16943429 26687479 27505670 27107012 32628469 33468080 26496610 27705803 22325352 33961781 24981860 23523425
PCGF1 RING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16943429 22493164 26687479 27505670 27705803 22325352 33961781 24981860
LAP2A LMNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22412018 10984438 19727227 16247757 16713569 28902428 24623722 29568061 26496610 34079125 30419336 12475961 16339967 24927568
CBX4 RING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 16189514 9858531 22078878 9199346 26496610 27705803 22325352 24981860 30317550
BCOR YAF2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CSN5 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28539160 11285227 17879958 16936264 24725084 16624822
UBP7 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22084066 23388826 31492752 17268548 16474402 26238070 30067985 22056774 17525743 21845734 22653443 31666375 11923872 24462112 29748603 29795372 16402859 14506283 20713061 21170034 30651545 16713569 16845383 20816748 17380154 31647545 32587091 23382381 25283148 26460617 32807901 15916963
P53 IF16 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11146555 30193098 21397192
UBP7 GUAA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30804394 30367141 15749019 26496610 24462112 19834552 26046769 33742136 19615732 26344197
BIRC3 TRAF2 â—¼   UBIQUITINATION ✅ - 0.9 0.9 Signor 18997794
TRAF1 TRAF6 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 8153045 21516116
PCGF1 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PCGF6 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BMI1 CBX4 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
RING1 YAF2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
DAXX PML â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CBX4 RING1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
MDM4 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 15604276 5217417
MDM4 MDM2 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 17159902 5219425
RING2 UBP7 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 20601937 26496610 22325352 20800574 24457600 25605328
DNMT1 UBB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
DNMT1 UHRF2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
RING1 RYBP â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
SMAD3 NOTC1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 14638857 16713569
BCOR RING2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16943429 26687479 27505670 33468080 26496610 27705803 22325352 24981860 24457600
MCM4 MCMBP â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
ANDR MDM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15640443 32801300 33332287 21157430 18332867 12145204 29755129 28708672 27903893 17974989 29402932 26973243 26196320 23132866 26411689 28151478
RING1 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
BMI1 RING1 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 7998286 20601937
PCGF1 RING2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16943429 32296183 22493164 26687479 27505670 29985131 18460542 26496610 26151332 27705803 22325352 33961781 24981860 24457600
PCGF6 RING2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22493164 12183370 12167161 21596310 26496610 26151332 27705803 22325352 33961781 24981860 24457600
RING2 YAF2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 32296183 27705803 26496610 22325352 33961781 24981860 20696397 27684187 24457600
DAXX MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 23405218 18566590 18583933 16845383 15364927 20195357 28875283 23038753 21134643
P53 MDM2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19303885 25417702 34408321 17268548 23252402 23880345 22807444 15094782 20962272 12529318 21726810 22124327 18981217 16173922 23318437 15558054 22524527 30584071 31626714 22301280 32516735 20174603 22912717 21075307 15848166 18566590 23483203 26882543 23402884 14671306 15001357 10889512 17908790 19411846 10640350 21561866 14499615 33503543 21986495 24998844 15908921 26673821 17098746 25362358 32066565 25739118 29295817 34362424 16595680 20591429 27336364 22745160 24462112 32427887 18467333 26578655 23261415 9271120 16055726 19357310 31591476 23169665 16338390 10608892 30464405 15542844 12612087 22266868 15550400 22331460 22914926 19071110 7686617 14559824 20959462 19941302 14596917 25512388 27129163 19597489 25609649 32904724 11351297 29121928 22487680 11709713 24127580 10562557 15358376 21584881 25312347 27826076 19098711 24980433 24413661 21887275 17116689 14612427 30948704 26001071 19857530 33061576 31138778 23802716 20234175 25313037 21988832 17616658 11744695 17666403 22525275 12897156 25156994 33020477 11925449 16152627 29876924 30244831 1614537 17363365 22474335 11112690 23443559 17297477 27905468 19085961 20479273 31940492 21261729 14517261 26908445 16866370 27893708 22653443 17470788 10488081 23370271 19223463 16751805 26556313 10734067 19411066 11223036 27856536 14704432 20124408 24240685 24842904 32901886 22948151 19234109 35140242 21084285 32894144 17848574 22737255 10561590 25168242 10435614 11697899 25543083 21572037 22920093 18604177 32874188 22659184 17591690 16845383 22444248 31239268 25283148 26186194 24200963 23826318 7689721 20047188 24314634 12167711 15308643 17318220 21857681 11431470 18815136 15950904 20705607 17525743 26876197 31177307 9529249 22374672 12915590 33650658 10601022 20837658 18223694 30097011 28205554 32334023 15247280 23776465 21268072 27308622 11713288 18234963 9582019 18784078 29487367 23776060 11713287 20484049 26720344 9131587 30109812 33961781 24361594 32807901 31066983 15824742 11562347 21454483 22157679 21088494 11070080 22575647 22083959 26540344 15210108 18332869 32528731 18172499 11094089 21132010 16414131 10827196 27031960 10892746 15280377 16023600 18665269 10202144 15058298 29549180 16212962 16905769 11278372 20657550 9809062 15295102 26238070 22391559 18061646 17310983 18485870 9278461 21925390 20659896 9824166 23150668 25637791 30598450 19160491 28605833 12690203 22467867 31594538 11572869 11384992 11486026 27807478 17936559 30679555 16678796 30252118 31652301 15144954 22411991 22084066 30175854 21478269 27543608 16624812 17290220 32097779 17301054 20694676 11714701 24667498 20395212 16547496 12381304 8058315 22266850 29755129 22085928 17159902 10196247 21316347 27886165 27215386 25384516 7926727 16964247 19081178 32198344 11046142 28549433 26350565 31533005 12867035 10321734 19590512 22991965 25277184 24207125 18541670 19166840 25103245 30320919 26883110 20235143 17139261 11597128 21071676 19568783 18813780 19805293 17056014 17989425 21317885 17234751 20588255 21170087 10347217 11839577 25954860 21060154 24926618 21750659 16331255 29269425 27811966 19305137 24659749 9450543 23201157 30879903 16870621 28362432 21149449 20570896 23609977 33765973 27106262 33355139 34040386 22588298 22389628 19033382 18264029 27462439 31092600 12208736 17369817 28082682 16579792 23246961 20708156 15013777 21465263 28542145 23572512 19483087 31665549 22975381 17438265 15604276 11178989 24488098 16432196 22227409 28628118 30005830 20639885 20847049 9363941 31406141 19816404 26475964 29899406 16861890 30320499 20660730 19332559 14702041 11284721 18316739 19837670 25464845 12426395 10681559 17302414 16107876 22510990 15154850 21098709 19106616 10722742 19188367 22366412 29524278 21084564 23134341 25624478 30455251 20173098 12620407 9223638 16713569 17426254 31647545 10766163 30454706 21471462 24621507 23652204 19153082 8875929 31152661 18309296 31968249 31796886 15122315 30532073 10980696 17080083 15064742 11285227 29547122 21965653 33495326 23728348 15242646 17347673 12842086 12944468 19255450 23671280 22916255 17875722 30355102 14741215 23946421 20591651 15053879 28514442 25241761 24567357 16215989 19656744 30832340 22262183 27249653 26203195 16857591 15313915 15933712 28223335 20542919 12552135 24643130 27282385 20080206 28553961 22819825 33579943 16159876 9724739 17380154 22318540 29997244 29670376 22103682 22032989 28394340 31903119
DAXX PML â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30292834 21482821 21474068 10669754 14517282 12529400 20972456 15350595 10545115 21779164 11244500 32545337 17081986 12595526 15710327 21840486 17419608 12150977 24637324 10684855 17360386 10525530 23222847
SUMO1 DAXX â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11948183 17081986 23395904 18583933 30958586 16475184 12150977 20972456 20927612 25409927 21816224 28851805 21474068 11112409 22578841 31879127 19465479 21383010
TRAF2 BIRC3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 30948266 10753917 21988832 9384571 20385093 19815541 20562859 8643514 16891304 16282325 24464131 8548810 11907583 21331077 27534557 23524849 15310755 23543740 16713569 23007157 33961781
RING2 BMI1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28073915 12183370 16710298 29402932 17157253 32296183 22493164 15386022 21772249 16751658 20601937 19636380 26496610 26151332 21676867 22902369 15563468 16359901 18650381 31093962 34316702 20543829 27647897 25843776 24457600 27705803 22325352 12589020 25355358 24981860 33961781 23207902 26468281 16714294
RING2 CBX4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21282530 18927235 26496610 27705803 22325352 16169070 24457600
RING2 RING1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16943429 15386022 12183370 21596310 26496610 22325352 24981860 16359901 24457600
RYBP RING1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16943429 28514442 10369680 16189514 25416956 32296183 34316702 27705803 34133714 22325352 30217970 33961781 26186194 24981860 17070805
RYBP RING2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16943429 28514442 10369680 32296183 34316702 26496610 27705803 22325352 33961781 24981860 26186194 20696397 30040487 24457600 17070805
BMI1 RING1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BIRC3 TRAF1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BCOR PCGF1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
PML SUMO1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DAXX SUMO1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BIRC3 TRAF2 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
TRAF1 TRAF2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DAXX P53 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 25241761 16713569 14557665 12954772 15364927 16845383 32545337 21482821 23038753 27626385 28875283 12482984 15339933 21134643
NOTC1 SUH â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 30975888 17636029 9111040 21475249 11390662 12644465 25609649 22325781 26496610 19907488 19800882 22143792 16530044 30967258 16682003 17526737 10637481 16713569 11997524 10713164 17284587 23103515 8749394 19321451 21820430 33961781 26186194 17573339 23022380 26033182 22100894
DNMT1 UHRF1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MDM2 MDM4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
HUWE1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26279298 16915296 34761308 16969074
PML KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19150978
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
DAXX MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21134643 16845383 15364927 18566590 23405218 18583933 20195357 23038753
MDM2 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19805293 22056774 17290220
MDM2 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 17145710 10218570 17616658 16511560 22266850 12874296 21925390 25825738 21988832 25512388 16227609 22493164 22902369 25659040 18219319 12963717 15604276 18566590 12370303 19838211 26359458 27617579 25809483 34551723 10608892 23028042 22120712 25703327 12860999 32300648 16055726 24813712 17301054 12483531 23671280 17159902 27621617 25105592 20484049 20724842 27215386 10827196 26001071 11606419 23946421 19683495 20705607 24755078 25384516 20473904 12393902
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
MYC AXIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC AXIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
SUMO1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22875967 9756909 25497731 17036045 21057547 18931695 19217413 8806687 16189514 17081985 11080164 11948183 9885291 19380586 17344210
PML SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 15356634 16189514 18988627
UHRF1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19798101 22064703 20210320 17673620 24368767 19800870 27049577 20613874 21268065 24782312 26065575 17934516 21045206 21745816 19308066 27045799
TRAF2 TRAF1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 DAXX â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 TRAF1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 DAXX â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 TRAF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF1 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRAF2 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 18997792 8643514 11907583 16713569 18621737 18997794 21988832 18606850 9384571 16891304 10753917 18981220 24464131 20562859 25241761 23543740 20385093 21331077 23007157 16282325 23524849 8548810 19815541
TRAF2 TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
AXIN1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11438668 23331499 18988627
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
ESR1 RELB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17369819 20034404 19433448
DNMT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21655924 20946668 17172825 15746193 22975348 12789259 19001520 24058781 23242655 22558281