GRB2
|
DBN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
LIMA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
IQGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PPP1CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
MYH9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
SYNPO
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
MYO1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
FLNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
FOS
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11350971
10984493
|
TP53
|
CSNK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12393879
11239457
|
TP53
|
DAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24217921
20943371
|
TP53
|
TNFRSF10D
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16230375
|
TP53
|
NDN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10713459
10347180
|
USP7
|
TP53
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5215220
11923872
|
SYVN1
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17170702
5219455
|
TP53
|
ANLN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
1301998
|
TP53
|
BIRC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16917513
|
SYVN1
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
ACTB
|
WDR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
WDR1
|
HSPB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
26465331
0133994
|
ACTB
|
HSPB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
26465331
0133994
|
CAPZA2
|
HSPB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
26465331
0133994
|
HSPB2
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18266962
|
STAT1
|
CFTR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19061877
|
DAPK1
|
LIMA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
AKT3
|
BMI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22505453
|
BIRC3
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23070005
18485876
|
CFTR
|
CANX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12208510
5215704
|
CTNNB1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24291232
24482235
|
WDR1
|
ATRX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ANLN
|
WDR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
PURA2
|
WDR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27684187
22863883
|
WDR1
|
POTEE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
WDR1
|
CH10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22863883
26344197
|
ANLN
|
MYH9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
FLNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
BMI1
|
LIMA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24457600
34316702
|
ANLN
|
SYNPO
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
COF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
LIMA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
ANLN
|
MYO1C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31586073
26496610
|
BIRC3
|
UBP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23524849
30948266
|
UBE2K
|
WDR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
UBP7
|
WDR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26496610
32601462
|
MYH9
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22366308
16186248
26496610
|
HDAC6
|
CFTR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31501480
22069321
14675537
|
NDN
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
CTNNB1
|
IQGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
GRB2
|
FLNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
17474147
12577067
21706016
|
CFTR
|
MYH9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
22038833
29924966
26618866
|
CFTR
|
LIMA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26618866
29924966
17110338
|
LIMA1
|
ACTB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
26496610
|
FLNA
|
MYH9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22939629
26496610
|
SRPK1
|
U2AF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
33961781
9472028
23602568
32707033
|
SOX2
|
FOXC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
35140242
23667531
28794006
|
GRB2
|
MYH9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12577067
20936779
24189400
|
BMI1
|
UBP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20800574
20601937
25605328
|
WDR1
|
COF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10366597
26344197
|
ACTB
|
COF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29892012
16189514
32296183
25416956
16713569
32015554
33961781
|
CANX
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
CFTR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
SRPK1
|
U2AF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
STAT1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24655378
14602726
|
TP53
|
SYVN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
TP53
|
TNFRSF10D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16230375
|
CSNK2B
|
WDR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TP53
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
USP7
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
5215220
11923872
|
TP53
|
USP7
|
â—¼ DEUBIQUITINATION
|
✅
|
|
0.97
|
0.97
|
mint
|
5215220
11923872
|
SYVN1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
FOS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
12738796
15067049
16393692
16394015
18039929
19667062
21385848
22634314
23430059
9064320
|
IQGAP1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
12446675
9694656
11734550
12377780
16622255
10473551
|
VCP
|
KEAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
33444648
11733065
28115426
15652483
10811609
29153394
|
TP53
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564862
20697347
20729811
21691299
19411072
24473123
20064927
18245266
18758483
18372914
|
TP53
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
8604347
17174366
8668332
1946467
10082525
10214938
1508692
8649776
10529369
12173040
|
TP53
|
USP7
|
â—¼ CLEAVAGE
|
✅
|
|
4.0
|
1.0
|
Reactome
|
16402859
15053880
16474402
11923872
|
NDN
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24722188
10347180
16713569
23785149
|
DAPK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
15355354
17297916
32266931
26626260
27753536
15254178
27681874
22112863
10734067
11883897
21386980
22815859
20851891
11244509
10733583
15542844
26742101
10673501
12091386
18246126
25584963
15489221
20959462
11258706
10801407
10606744
11707453
17339337
12111733
17977830
25229255
34168813
|
CSNK2B
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10606744
11709713
10214938
10951572
16713569
11551930
10747897
10673501
11883897
|
PPP1CB
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16501611
15178317
|
USP7
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
26460617
21845734
23382381
16713569
25283148
15916963
18375498
19918835
24462112
22056774
17268548
22653443
23388826
21170034
20816748
17525743
16402859
11923872
17380154
16082221
26238070
16845383
16474402
35538032
22084066
|
MYH9
|
PPP1CB
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|
CSNK2B
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12432063
|
STAT1
|
FOS
|
â—¼ UP_REGULATES
|
✅
|
+
|
20.0
|
1.0
|
ACSN
|
11134049
11830590
12193701
12223527
12796776
12811837
12967644
14607900
14764699
15814715
17016554
17513775
17559085
17689680
18272812
19833085
21263073
21930765
25960930
8683106
|
STAT1
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8874187
7510676
8830676
12600988
7507205
8770944
17558387
|
AKT3
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|