Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CREB5 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8378084 8440710
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
MAPT TUBA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1421571 16687396
RHOA OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20553488 7717051
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD4 PSMC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
VCP PSMC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMC1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMC1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAD TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
FAF2 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
VCP FAF2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PGK1 PCNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
LRRK2 UQCRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
HTT NCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDPK1 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12783890 10753910
LRP6 RIPK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 16273260 23371553
LRP6 RIPK4 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 16273260 23371553
PDPK1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PSMD4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1B SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NMES1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AGK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RYBP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NXT2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT TALDO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT AKR1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT TGDS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
HDAC5 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23899560 22991226
ERBB4 PIK3CD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 17496910
ESR1 ADA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11357058 18414489
ERBB4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16912174
RYBP SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RYBP SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHRM5 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
UQCRB VDAC1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CALM3 SNCA â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
COX4I1 UQCRQ â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HUWE1 PCNA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25147182 22203964 27146073
CDC42 MAP3K11 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
TNNC1 TPM1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
LRP6 AXIN1 â—¼   RELOCALIZATION ✅ - 0.81 0.81 Signor 18632848
EP300 ATF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10327051 24069158
FAF2 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25147182 18775313
ESR1 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
ESR1 PLOD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25604459 31527615
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
AXIN1 AXIN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22682247 20128690
LRRK2 RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 21454543
LRRK2 AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 LDHA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 VDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 21370995
LRRK2 TPR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
VDAC1 AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 29128334
ESR1 STOM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26487511 31527615
ESR1 TPM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
MTMR7 MTMR8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOJ CDC42 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31871319 10967094
FAF2 STOM â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CALM3 ESR1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
COX4I1 UQCRC1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CREB5 ATF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 8440710 28514442 26186194 33961781
COX4I1 UQCRFS1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
HIBCH SOD2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MT-CYB NDUFC2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
NDUFC2 UQCRC1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
NDUFC2 UQCRQ â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
NDUFC2 UQCRH â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ATF2 MAPK11 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ESR1 PSMD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25604459 20348541
LRRK2 CDC42 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
PSMD1 VCP â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
OTUB1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26752685 18954305
LRP6 FZD8 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11448771 11029007 15908424
ESR1 DNM1L â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19805454 21217774
COX4I1 NDUFA4 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
NDUFC2 UQCRB â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
NDUFC2 UQCRC2 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
NDUFC2 UQCRFS1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
NCF1 PRKCZ â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
PGK1 PCNA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26030842 20849852
LRRK2 LRP6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27013965 22899650
PARK2 PSMD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CACNA1A CALM3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ATF2 CREB5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AIMP2 PARK2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARF6 APBB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 24056087
MLF2 AIFM1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 29568061
MAP1B LRRK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24754922 21159966
KLC3 KLC4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26496610
PSMD4 VCP â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
AXIN1 LRP6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22682247 19107203 23959799 24976009 28966723 16890161 20128690 23892894
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
SDHD SDHA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23747254 25564869 23564345
NCF1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
RHOA ERBB4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
LRRK2 DNM1L â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22228096 22639965 24282027 29541021 23813973
PDPK1 AKT2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9228007 9094314 15890450
PRKCZ AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18353613 9512493
ESR1 TYMS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10875244
ESR1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23167795 16423895 19366879
PSMC1 VCP â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
AXIN1 LRP6 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CYC1 NDUFC2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CACNA2D1 CACNB2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SOD1 SOD2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
COX4I1 CYC1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
PAFAH1B1 PAFAH1B2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
PSMD4 PSMD1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 19781552 16990800 22863883 33961781 30479383 22939629 26344197
FAF2 VCP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PCNA SPRTN â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
COX4I1 UQCRC2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
UQCRC1 UQCRH â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
UQCRH UQCRQ â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UQCRC2 UQCRH â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
UQCRC2 UQCRFS1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CYC1 UQCRQ â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CYC1 UQCRC1 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
CYC1 UQCRC2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
PRKAB2 PRKAG1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CYC1 UQCRFS1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CYC1 UQCRH â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CYC1 MT-CYB â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CYC1 UQCRB â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC1 PSMD1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UQCRC1 UQCRFS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UQCRC2 UQCRQ â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMC1 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD1 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAPK11 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 17145710 17081983 20506250 19690332 19413330 17079470 11566021 10085140 17254968 10777545 7535770 7839144 21614932 16393692 15304344 17380123 7737130 15192015 18669648 15187187 15140942 9235954 12110590 17258390 19436832 9155018 9430721 9029150 14734562 11274345
AKT2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17964260 16926151
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
LRRK2 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22924508 24113872 26123245 24165324 25977830 22303461
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
LRP6 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20128690 23331499 8666229 12897152 10428961 24976009 16890161 18632848 22682247 23959799 16340998 18988627 19107203
AIFM1 NDUFA4 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
NDUFA4 NDUFC2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
AIFM1 NDUFA4 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
NDUFA4 NDUFC2 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
AIFM1 NDUFA4 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
UQCRC1 UQCRC2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
UQCRC1 UQCRQ â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
NCF1 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 16778989 25877926 14530365 27558335
PRKCZ NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626435 12734380 96198102 11145703 12056906 94375440 8089108
LRRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20127702 22924508 22658533 24907399 19576176
FZD8 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11448771 21078818 11029007 20093360
CDC42 MAP3K11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10559936 16253996 23331499 15020669 11340065 15003621 10934474 11413130 17161586 25241761 11950587 9427749 10799501 9829970 11248548 8910292 18719708 10613909 10461188
CDC42 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23109003 17353362 10733591 10873802
PDPK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12887331 14500673 11222751 18691976 10075713 20332120 9768361 9748166 17335005 10357815 16189514 11141077 16051884 11781095 10764742 14604996
PDPK1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 15743829 15191648 10679787 23331499 19203586 15718470 26491696 26937223 9374542 24169049 15890450 28589878 9512493 12048203 10822383 12434148 20059950 11134526
AIFM1 NDUFC2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFC2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
AIFM1 NDUFC2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 15526035 16200211 16218961 16489074 17344420 20025615 20816094 24684389
PRKD1 HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 21357900 22865920 28681592 16584705 11114197 25514029 26137861 20621068 19655095 25362149 15367659 11081517
ESR1 PSMD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18457947 9253789 12648521 11696545 23580568
MAPK11 MAPKAPK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15187187 23331499 18039929 9628874 23180781 19690332 12738796 11274345 18669648
AKT2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11139588 11432835 11507039 9528769 7838153
COL3A1 P4HA1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 2543975 16591531 1323838 14500733