CDK1
|
MAPK6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
18235225
20236090
|
MYC
|
RAN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23468463
11085504
|
MYC
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11318876
10528192
|
MYC
|
KPNA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
35044719
17093053
|
RAE1
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17172455
0609582104
|
RPA1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
24782567
20705237
|
MAX
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7969121
10348347
|
TP53
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15230856
8732672
|
TP53
|
ZDHHC5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
28775165
|
TP53
|
PTMA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9185588
18856068
|
XPO1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17268548
17891139
|
MYCN
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20145147
|
RANBP1
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12649209
5216249
|
H4C6
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RAN
|
H4C6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RCC1
|
RAN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7878053
1944575
|
RAN
|
RANBP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
9637251
|
H4C6
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
20023648
22508508
|
STK3
|
RCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19559616
|
NUP88
|
NUP214
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H4C6
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RCC1
|
H2AC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HMGA1
|
H2AC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HMGA1
|
H4C6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
H2AC4
|
H4C6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1003064107
20498094
|
RAN
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
NUP35
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
NUP107
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
NUP35
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
VCAM1
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
MYC
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
IMB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
RBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
VCAM1
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
RAN
|
DLGP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAN
|
IMA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAN
|
RGPD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FOXA1
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25609649
27926873
|
VCAM1
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
RCC1
|
DLGP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VCAM1
|
NUP93
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
H4
|
UBC9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
14578449
30804502
|
VCAM1
|
IMB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
RANG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
IMA3
|
IMA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
26344197
|
VCAM1
|
XPO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
VCAM1
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
NUSAP
|
RBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
KPNA4
|
RANBP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
NUP107
|
NUP210
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
RANBP1
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
MYC
|
XPO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
17314511
26673895
32140074
29467282
|
UBC9
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26496610
|
UBC9
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26496610
|
RCC1
|
RGPD5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RCC1
|
NAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RCC1
|
RGPD8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RCC1
|
RBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RCC1
|
RGPD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
RCC1
|
NUSAP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NUSAP
|
IMB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
26186194
26496610
|
RANBP3
|
XPO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
EP300
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12649209
33742100
|
RANBP1
|
XPO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
NUP153
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
H2AFY
|
HIST1H4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
HIST1H3A
|
HIST1H4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
HIST1H4A
|
HIST2H2BE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
HIST1H4A
|
HIST2H2AC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
HIST1H3A
|
HIST2H2BE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
NUP155
|
NUP85
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
NUP153
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
RCC1
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
30021884
30804502
20347844
|
RCC1
|
IMA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
17855385
33961781
26186194
|
DLGP5
|
IMB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
28330616
26496610
|
TP53
|
XPO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
EP300
|
HIST2H2BE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
EP300
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11163245
16096645
30804502
16109717
25728767
11884585
15951563
15611041
11830591
28465257
16415179
11689053
15308690
28844863
26625199
15136563
17982102
18397880
12499368
23587423
20368990
11689448
12237408
11983172
16717280
14752096
22100137
14612423
8945521
16287840
18418072
30902546
15834423
23934153
14585496
11691934
10607594
16332960
|
RAN
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
30804502
30021884
|
NUP85
|
IMB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24927568
26496610
|
RCC1
|
H2A1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
27248496
30021884
|
HMGA1
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
30804502
30021884
|
RANBP2
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
KPNA3
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
MYC
|
EP300
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15616592
16287840
32140074
16126174
17157259
12776737
|
RGPD5
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
11774384
33961781
21988832
|
NUP85
|
NUP98
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24981860
24927568
26344197
24315095
|
NUP43
|
NUP98
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
24981860
26186194
24927568
|
IMA3
|
NUP50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
32296183
25416956
33961781
|
IMA4
|
NUP50
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
25416956
33961781
26186194
|
CSNK1A1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
RANGAP1
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
NUP155
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
TP53
|
VRK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
NUP107
|
NUP35
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
KPNB1
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
TPR
|
NUP98
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11248057
12802065
|
HIST2H2AC
|
HIST2H2BE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
NUDT21
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
RCC1
|
XPO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
EP300
|
PTMA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11967287
10891508
16713569
|
MYC
|
NUP93
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21150319
17353931
29467282
|
RANB3
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11932251
9637251
16189514
26344197
|
IMA3
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16189514
16713569
33961781
26186194
10744690
|
RCC1
|
RAGP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
|
CDK1
|
RANBP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26051540
17570479
|
CDK1
|
NUP50
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19767751
|
EP300
|
TAL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11756538
11118214
10490830
|
RPA1
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
TP53
|
VRK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17689819
16782868
18612383
|
RCC1
|
NUDT21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RANBP2
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9398662
10473610
|
RCC1
|
CHGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
TUBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
NUP43
|
NUP85
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
15146057
33961781
24981860
26186194
24927568
26391640
24315095
|
NUP88
|
NUP98
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22480613
33961781
12589057
28514442
|
IMB1
|
NUP98
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33097660
9144189
26496610
9275187
25562883
26344197
|
CRELD2
|
MAPK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
HOXD8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
ZNF135
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
APLP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
CRELD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
CSAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
PKM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
KMT2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RCC1
|
TRMT2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RANB3
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11932251
9637251
16189514
26344197
|
XPO1
|
RCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
11932251
|
UBC9
|
RBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11709548
28514442
22194619
16713569
17353931
26261240
26496610
19785004
12192048
15931224
33961781
11792325
20936779
22464730
15608651
|
UBC9
|
RAGP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
21988832
29773808
20719936
18538659
18691969
16732283
21139563
9497385
26496610
14578449
18706886
16820290
22194619
29127148
17353931
11853669
16194093
12924945
17036045
28695742
32780723
31575873
16713569
23395904
19549727
15931224
33961781
21098080
20501649
|
NUP50
|
IMB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
12176322
26496610
33961781
|
IMB1
|
IMA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20818336
16713569
26496610
10523667
9435235
|
IMB1
|
RBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9398662
8909533
26496610
10473610
11266456
12894213
|
RANB3
|
XPO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12176322
31326389
11425870
20026644
|
H2A1B
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27248496
31142837
33961781
20498094
21743476
30021884
|
RAGP1
|
RBP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11709548
22194619
21518904
11854305
9019411
12192048
22464730
16204249
26344197
|
NUP107
|
NUP153
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
NUP155
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
KPNB1
|
RANBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
MAX
|
MYCN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
NUP214
|
XPO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
KPNB1
|
RANBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
RANBP3
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
KPNA4
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
NUP107
|
NUP155
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ POLYUBIQUITINATION
|
✅
|
-
|
0.91
|
0.91
|
Signor
|
12690203
|
IMB1
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
28514442
17855385
33961781
26496610
|
TP53
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
EP300
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
KPNA3
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.93
|
STRING
|
36370105
|
NUP205
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
NUP98
|
XPO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
NUP188
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
H2AFY
|
HIST1H3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
NUP155
|
NUP205
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
XPO1
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
11932251
26344197
|
RANG
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
7616957
33961781
26186194
22939629
|
KPNA4
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
RAN
|
RANGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
UBE2I
|
RANGAP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
17036045
5219211
|
RANG
|
XPO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
22833565
10601307
26344197
10779340
|
KPNB1
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
NUP43
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RAN
|
RANBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
RAGP1
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
16189514
9219684
20805321
10394366
7744835
33961781
8146159
|
RANG
|
IMB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10037787
20658144
10779340
8909533
26496610
9045717
10473610
|
NUP153
|
NUP50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
KPNB1
|
NUP153
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
RANG
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7882974
11832950
10779340
20805321
9315840
7891706
9111043
12649209
33961781
10811801
22939629
7603572
26344197
|
XPO1
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
32585100
21909257
10779340
10944119
27613868
12070164
20026644
9323133
22939629
26344197
|
RBP2
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10318915
28514442
11470507
21988832
24855949
10078529
33961781
26344197
7603572
20547757
|
RAN
|
RCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
16189514
7882974
12194828
31467278
10827954
1961752
18617507
11336674
20565941
7988569
10811801
22939629
10369786
29997244
7891706
33961781
26186194
26344197
|
IMA4
|
IMB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10523667
20818336
26496610
26893479
|
RPA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
NUP107
|
NUP43
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
NUP43
|
NUP85
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
NUP85
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
NUP43
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
TP53
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16611888
6599495
|
NUP155
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
RANBP2
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
RANBP2
|
RANGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
NUP214
|
NUP88
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
RAN
|
RANBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
MYCN
|
MAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
2006410
23792191
26062444
24859015
10229200
1935896
18003922
18488021
27728805
10597290
29028833
25175806
17289033
20946988
|
NUP205
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RAN
|
RCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
NUP107
|
NUP98
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
NUP98
|
RAE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
RANGAP1
|
UBE2I
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NUP107
|
NUP85
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NUP85
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NUP98
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
KPNB1
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RAN
|
XPO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
NUP107
|
SEH1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
EP300
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MAX
|
MYC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDK1
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
14551205
15279786
17102137
17116885
17296725
17303408
17582221
17660363
18414028
18590585
19793801
7575488
|
MYC
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18802399
2237430
8065306
11085504
|
TP53
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
10825186
11593387
12874009
19472317
10514438
11313928
16807237
8270002
17942917
9275177
20395210
11032828
19861536
12889596
19067706
|
CDK1
|
RANGAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15037602
17570479
|
CDK1
|
NUP98
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21335236
25247763
|
CDK1
|
NUP210
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18669648
20068231
8672508
|
CDK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
24173284
12767922
1584757
20661218
26029996
2141171
9467949
17570479
20808790
7862459
11327730
11078726
27726420
8357826
16713569
2156209
|
CDK1
|
HMGA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
17081983
20068230
17924679
17960875
20068231
2168176
17570479
1939057
19413330
20123066
19664995
18669648
15302935
|
CDK1
|
RCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
34356619
18568422
15014043
17855385
17570479
15203004
|
CDK1
|
MAPK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20236090
|
EP300
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
137.0
|
1.0
|
Omnipath
|
11907332
25545885
21187340
10706102
16438982
10490106
19339993
15542844
23010591
11433299
19608861
17438265
17906639
16024799
9194564
20234175
23402884
12162806
26229107
16959611
15186775
9744860
11070080
17977830
17189186
22266186
20228809
15664194
19805293
25753752
11804596
26625199
27818144
10648616
16928824
9288740
10942770
12724314
23148227
23728348
15965232
19218448
16678111
16782091
20094059
14612423
24821727
10518217
16713569
9891054
25288747
17452980
14759370
19788416
25156994
18931695
22074660
23880760
15337767
15509808
26302407
22731250
18391200
16543236
19234109
21471221
23307557
25867071
12690203
15558054
18612383
23870121
18243116
19217391
22013068
16537920
16611888
18485870
9194565
12660246
9809062
23796514
11359905
12501250
15295102
19407812
25651062
23329847
16135789
|
EP300
|
H4C6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19423655
11689053
16332960
|
EP300
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
22290435
19623618
11804596
23343194
22761862
16039586
12776737
17157259
17143292
12660246
15576399
21151179
15522869
17306568
19407812
17666529
21285352
19619488
|
MYC
|
MAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
11274345
12040186
15121849
16908182
2006410
8425218
|
MYC
|
MAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16596619
21988832
10229200
17471507
26267534
15572685
18003922
20382893
35140242
17418410
25609649
16352593
31767764
17072308
17289033
10918583
9528857
14749374
21807113
19623651
18620061
25522242
32296183
16140957
16705173
19578763
26496610
12584560
17157259
17643117
24951594
20946988
10465786
12706874
12821782
9184233
17353931
10611234
32140074
8266081
20691906
16410719
21150319
10593926
12660246
27859590
12553908
8224841
10319872
2006410
16287840
16606833
23816886
9708738
17314511
9886493
27705803
33298911
33961781
20936779
12824180
9680483
17700062
29467282
30415952
12391307
|
MYC
|
MAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11274345
12040186
15121849
16908182
2006410
8425218
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
MYC
|
NUP155
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12747840
18414489
|
MYC
|
FN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
14519204
11896591
8376401
10421838
|
MYC
|
H4C6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12747840
12695333
|
MYC
|
PTMA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8196628
15840017
8378090
1378271
8524267
12695333
9185588
10380878
9365169
17372028
|
MYC
|
MAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10508165
15665468
8385351
8649388
8521822
22384171
1406956
17341548
|
MYC
|
RCC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9178906
14519204
9792927
12695333
|
MAX
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
90.0
|
1.0
|
Omnipath
|
17145710
16287840
25609649
12821782
16606833
16596619
21807113
25522242
20691906
19578763
24951594
8224841
17643117
9528857
12391307
16705173
21150319
10229200
21988832
15572685
9680483
2006410
17314511
14749374
12553908
17289033
17418410
19623651
12824180
17157259
12584560
26496610
20946988
20936779
8425218
23816886
17353931
10319872
17471507
18003922
16140957
20382893
12660246
8266081
7565735
32296183
10465786
26267534
17072308
27705803
9184233
18620061
10918583
17700062
10593926
10611234
16352593
9708738
|
RAE1
|
NUP98
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
19615732
26186194
18832153
35096974
16036565
10209021
15851029
17172455
24927547
20498086
21467841
888800000819
|
MYCN
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20811720
11107122
10050884
21862876
20145147
19885598
|
DYRK2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
111.0
|
1.0
|
Omnipath
|
29296831
21383696
14749479
11740489
20171273
25778922
15843377
33906076
10581258
15750624
15897882
15706352
26236013
24899407
33572115
17906639
20935676
24379358
17386256
15870257
26346493
12427754
34103685
17567906
11101524
17210684
18536714
15381073
19965871
26578795
26087959
28060750
21765464
20673369
34216619
16601678
17380123
33443163
18216278
21642861
15526030
22878263
17349959
16738336
20696760
19882354
16219768
17105820
16793543
17332358
24901999
16247456
24196445
26804244
15657359
27208501
18056705
21765463
23420876
22797063
16377624
19861417
18160537
12676607
20123963
15489221
17591690
20514025
23149944
19857493
17891183
27034505
11780126
21057547
25944899
26341817
17349958
20962272
22525275
19828042
12902982
19465479
15471885
15322239
11495913
12907596
32083004
25915850
20018442
24145406
26029824
21394211
12093737
33872315
20610713
20024960
26113041
20811699
18560558
21660965
16717128
11030628
17107963
|
VRK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
18612383
12782311
29340707
11551930
11883897
29679095
11709713
18286197
24126608
26412148
15542844
28927264
10747897
10673501
24731990
26706601
10606744
10951572
24492002
|
CSNK1A1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
10606744
9765199
20041275
11709713
18246126
27681874
10951572
29793495
10734067
11875057
10747897
10673501
11883897
11551930
|
XPO1
|
RAN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
17081640
15574331
16608852
11231581
9837918
11451485
8113738
11124902
11932251
11289803
|
IMB1
|
RAN
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
8576188
9102465
10037787
28514442
10779340
20658144
10944119
11024021
8909533
9214382
26496610
9135132
9045717
33961781
22939629
26344197
|
RANBP1
|
RAN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
10779340
11832950
12649209
9111043
10811801
7603572
9315840
20805321
7891706
|
RANBP2
|
RAN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21988832
24855949
10078529
7603572
20547757
11470507
10318915
|
RANGAP1
|
RAN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7744835
8146159
9219684
16189514
10394366
|
RCC1
|
RAN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
26186194
10827954
11336674
18617507
10811801
29997244
31467278
16189514
7988569
10369786
20565941
1961752
|
RAN
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
10779340
8909533
11024021
9214382
20658144
8576188
26496610
9102465
9135132
10944119
10037787
9045717
|
NUP98
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9144189
25562883
9275187
|
NUP153
|
KPNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
35044719
10749866
|
UBE2I
|
RANGAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
23395904
16194093
16713569
18691969
18538659
21988832
21098080
21139563
17036045
11853669
22194619
15931224
26496610
19549727
9497385
16732283
20501649
17353931
20719936
12924945
16820290
14578449
18706886
|
RANBP2
|
RANGAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
16204249
9019411
11854305
19526197
22464730
12192048
22194619
11709548
21518904
|
RANBP3
|
RCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11932251
9637251
16189514
|
FOXA1
|
H4C6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
Reactome
|
18533032
27062924
21151129
16009131
16087863
16980581
21934649
16113099
18358809
22056668
23172872
15282324
21878914
23192763
|