Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MYC AIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
TIMM50 ARAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216198 12620389
SYK CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
HTT CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN3 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT8 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
PAFAH1B1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSP90AA1 CRMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 DNAJA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
HSP90AA1 PAFAH1B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20133715
KPNA1 CSNK1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12062430 5215475
HIF1A LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 21454812
PLK1 MAGED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAPT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0709180105 18292230
MAPT TUBA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1421571 16687396
MAPT TUBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24905733 24251416
MATR3 HTR7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MATR3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MORF4L2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC STIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFATC2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23858296 22333584
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18809243
MYC HSPA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC NOP56 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
CDC73 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18987311
MYC MYO1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17353931 17093053
NCOA6 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810100105 19047629
NFATC2 NFATC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19564342 11786533
PLK1 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7996327 20869364
VAV1 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
VAV1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PFDN5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
INCENP PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19228686
RAD52 RAD51 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216387 12750383
RUVBL1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18087039 0710343105
SLC25A11 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SQSTM1 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15983046 22872865
ACTB HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VAV1 SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
AKT1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15461588 17570479
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9199305
GZMB HAX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20388708
HSP90AB1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A PFKL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8089148
SP1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
TPSB2 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK1 NXPH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCK1 ECT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 CRMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18524846
SP1 DPYSL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15207709
PKN1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1218925110 23223530
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1A VPS4A â—¼   COLOCALIZATION 2.0 0.8 intact 17853893 6169256
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FASN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TTC1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DPYSL5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DPYSL2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AFG3L2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CRMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
BCOR HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10898795
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32803659 21295277
HSP90AB1 DNAJA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
YWHAQ HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
ESR1 B4GALT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14605097
HSPB1 DPYSL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 TTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPS4A PDCD6IP â—¼   COLOCALIZATION 2.0 0.8 intact 17853893 6169256
HSPA5 DSP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 DPYSL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STIP1 EML1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STIP1 DNAJA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
HIF1A HSP90AB1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
YWHAQ CBL â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8005785 11697890
MORF4L1 RUVBL1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ARAF HAX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 29777862
ARAF CALU â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29777862 25852190
ARAF DPM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29777862 25852190
ARAF AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29777862 25852190
TTC1 BAG2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
MYO1C CBL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19380743 9367879
MYC MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
CUL1 MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 21145461
MATR3 BTF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 33644029
CDC73 MYC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 26687678
MYC MRGBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 35140242
MYC FLNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC ECT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC FAF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC SYK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC WDR82 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
PAK1 ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16452229 12374744
CUL1 STAU1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30948266
STAU1 NOP56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 30948266
STAU1 ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15121898 23125841
ITGB1 FLNA â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5226870 17690686
CYLD FLNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27591049 31762063
PGAM5 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 17046835
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
ESR1 OTUD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 BCOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26487511 31527615
ESR1 NACA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
NDEL1 OFD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAB8B SYTL4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HSP90AA1 STK11 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ARAF BAG2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29777862 31980649 25852190
AGO3 FKBP5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MYC HSPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
MYC DPM1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
SOCS6 IRS4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12052866 28883622
GAN CUL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 15983046 31944090
FAF2 UBAC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26424800 26389662 22119785 23297223 31073040
HAX1 MAP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
BCOR HDAC6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 10898795
ESR1 ACTN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23403292 21182205 19805454 31527615
CTBP1 BCOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 35016035 26186194
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11839798 29467282
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
AKT1 STK11 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 24412244 28205554
AIFM1 HAX1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
AIFM1 SCO2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 29568061
PEX14 TTC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 21525035
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HTT SQSTM1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CTNNB1 RUVBL1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CCT8 PFDN5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
FKBP5 ARAF â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 29777862 25036637 25852190
STK11 FKBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 25036637 14676191 20562859 33961781 25852190 32707033
PRDX1 MYC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12196529 29467282 21988832
ESR1 RBBP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21502505 16603732 31527615
ESR1 FLNA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21182205 19805454 25604459
AIFM1 PGAM5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34079125 27218139 29568061
AGO3 AGO4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 19167051 24778252
POC1B CEP44 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32060285 26638075
HSP90AA1 PPID â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
MORF4L2 MRGBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CRMP1 DPYSL2 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
DSG2 JUP â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
HTRA2 HAX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31617661 17906618
MYC IRS4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17314511 30415952
MYC MYO1B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 29467282
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
GAN TBCB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28393858 16303566
AGO3 OTUD4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29395067 19167051
CCT2 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT4 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT5 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT6A PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
FKBP5 MAPT â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CENPJ TUBA1B â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
ESR1 FKBP5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27483141 9222609
AKT1 PAK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24886428 23397142 14749719 12138087
ESR1 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 20308691 19805454 21182203 21182205 20348541
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
HDAC6 CYLD â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19893491 20593489
CEP97 SUGT1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 25036637 22261722 26638075
OFD1 FOPNL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 26496610 26638075
ACTB MAPT â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CEP290 IQCB1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CBL VAV1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MORF4L1 MORF4L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AIMP2 PARK2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MYC PFDN5 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HDAC6 SQSTM1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
KATNA1 KATNBL1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSP90AB1 MAPT â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ITGB1 TLN1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
NCOA6 RBBP5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CBL YWHAQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ESR1 NCOA6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
FLNA ITGB1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MYC PLK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27773673 17314511 33494392 29467282 30415952
PAK1 SCRIB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 31980649
PLK1 CEP97 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19596235 32707033 25659891
PLK1 OFD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26638075 21988832
FLNA ARRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17984062 16611986 17620599
PKN1 ACTN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9030526 16189514 16713569 11802708
ESR1 BTF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31527615 18025262
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CBL NCK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CTNNB1 JUP â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
DPYSL2 DPYSL5 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
DPYSL2 DPYSL3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CRMP1 DPYSL3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HSPA8 MAPT â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HSPA5 SQSTM1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
STK11 FKBP5 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 34591612
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MYC SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11274368 18003922 17418410 15780936 32115405
MYC NOP56 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 17314511 30415952 29467282
NCOA6 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10866662 16794079 10567404 10681503 11773444 26487511
WDR82 RBBP5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31076518 20516061 23870121 23508102 24981860
HIF1A SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 17024177 17418410 15780936
DAG1 NCK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17474147 11724572
AKT1 HSPB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17510053 31980649 12740362 11042204 23397142
DPYSL3 DPYSL5 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
DNAJB11 HSPA5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HDAC5 YWHAQ â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MAPT TUBB3 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
MRGBP RUVBL1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
AKT1 RICTOR â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MATR3 AIMP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AIMP2 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SYK AIMP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 25416956 21988832 31116475 19584093 21536907 32296183 31792442 26264872 12819782 9878398 22939629 24212136 21900206 29997244 32814053 33961781 22751010 26344197
PAK1 ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15710605
NCK1 CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16503409 10204582 24287595 11494134 7517397 10967110 10829062 10372803 33961781 9851874
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CRMP1 DNAJB11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YWHAQ ELAVL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8008479 18593881 1645808
HDAC6 ELAVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18644987
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
HTRA2 HAX1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11803371 15371414 23070005
AKT1 HTRA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17311912
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC SLC25A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ASCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PPID â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333 11085504
MYC FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14519204 12695333
MYC PEX14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
NCOA6 RBBP5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17178841 19433796 17925232 12482968 17500065 23870121 23508102 33961781 24981860 19047629
STK11 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20400510
PLK1 PPID â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PLK1 SUGT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21864708 22869522
CTBP1 RBBP5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
SP1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22412893 23995788
SCRIB TLN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
ITFG1 CDC73 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SYK TUBA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8617742 10862713 8566014
AKT1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16256741 10896934
FLNA VAV1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 16849481 21277899 27242793
HIF1A TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18178340 21176881
SP1 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9677424 9325332 8955122
SP1 B4GALT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17557191 17656364
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
POU5F1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284 20683952
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
STIP1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21170051 27353360
DPYSL2 DPYSL4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DPYSL2 CRMP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CTNNA1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKAA1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23291169
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP5 WDR82 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CTNNA1 JUP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
KATNAL1 KATNBL1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
AKT1 ARRB2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 18191226 19122674 19262695
STIP1 HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ - 0.92 0.92 Signor 27353360
SYK VAV1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 11331248
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ACTB RUVBL1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NCK1 PAK1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
TUBA1A TUBA1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CBL SYK â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
KPNA1 KPNB1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
S100A8 S100A9 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
BAG2 HSPA8 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
MORF4L1 MRGBP â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PAK1 NCK1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11278241 10805734 8824201 11157752 10026169 10330411 10372803 33961781 9851874 11557983 15784622
NACA BTF3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10982809 30948508 33644029 21203952 33961781 24981860 26344197
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
KATNA1 KATNB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
NDEL1 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
HSP90AB1 SUGT1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
RAD52 RAD51 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28551686 10448035 8550550 10212258 9837724 20190268 17118963 9826763 12750383 10666456 15766559 19338310
SYK VAV1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SMG1 UPF1 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 23356578
HSP90AB1 STIP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HSP90AA1 STIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RPS27 RPS9 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
BTF3 NACA â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FAF2 UBAC2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
HSPA8 STIP1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
HSP90AA1 SUGT1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMG1 UPF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PFDN1 PFDN5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
INO80 RUVBL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
CBL VAV1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11353765 15169881 18835194 20189481
VAV1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19635790 20940296 16289966 23331499 16356860 11133830 23180781 11331248 12881521 18835194 9200440 16713569 11313921
SYK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 72.0 1.0 Omnipath 16289966 15922744 9525940 19419964 11133830 33512474 18273061 10829062 10799548 10540342 10934191 7721825 12435267 11331248 12604776 9890970 11042121 10092522 11997497 12522270 9857068 9988765 15556646 11742985 15536084 8621719 9102067 22880054 10551821 11239464 10617633 11994282 10570266 12881521 9535867 15577829
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
TP73 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12766778 18555006 11870517 18829110 11309270 14733783
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
SP1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10649433 22025288 15067344 17370299 21830402 17225865 12134028 19115249 16239970
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
DNAJC7 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875381 20661446 12853476 15189447
ELAVL1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18519672 19574298
STIP1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 10642522 21235734 21360678 26804907 11413142 24949977 19875381 10786835 20704274 21170051 26496610 27353360 25036637 19996313 9452498 18285346 24462205 22315411 20159553 22729780 22504172 11877417
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
KPNA1 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11032817 26491019 10523667 26496610 9922449 9102465 17596301
F9 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11560943 1156094312522210 12522212
SYK MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 20110615 22482453 18070606 28877763 30538427
PKN1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 9565682 11181841 9614189 9832145 11104762 12387894 12226093 19562805 12714590 19857203 12435421 9546672 9771888 19413330 9199504 8999860
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16596619 21988832 10229200 17471507 26267534 15572685 18003922 20382893 35140242 17418410 25609649 16352593 31767764 17072308 17289033 10918583 9528857 14749374 21807113 19623651 18620061 25522242 32296183 16140957 16705173 19578763 26496610 12584560 17157259 17643117 24951594 20946988 10465786 12706874 12821782 9184233 17353931 10611234 32140074 8266081 20691906 16410719 21150319 10593926 12660246 27859590 12553908 8224841 10319872 2006410 16287840 16606833 23816886 9708738 17314511 9886493 27705803 33298911 33961781 20936779 12824180 9680483 17700062 29467282 30415952 12391307
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401
MYC ITGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11381265 16878156 12695333
MYC NME2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15530864 14519204 11960382 19435876 18414489
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
NFATC1 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19915002 18078995 15657420 18299389 16455648 11402342 11030334
NCK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 10805734 11278241 10026169 23109003 11096073 10330411 8798379 11278553 16490784 11157752 15784622 9024622 9755165 8824201
AKT1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11435472 14749719 24886428 14585966 23397142 9032240 12138087
PAK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18521086 26944939 16778166 18755239 21893191 15178330 19205871 29548483 26554417 27003261 24505617 16452229 15193262 19557173 15642175 12374744 19465939 17604944 25447917 20179234
PAK1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 12872159 16999872 18354494 20361981 23291169
PAK1 TBCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15831477 18048340
PAK1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 28007610 28423670 23543898 25639486 26547035 22369945 23162742 25472536 21822311 25225063 27713506 27910850
PAK1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 18598695 18088087 24278701 12198493 26009991 15024089 25472536 23246867
PAK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26779436 18427546
PLK1 TP73 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 18418051 23948487 18174154 22084676
PLK1 ECT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17332740 18669648 16247472
RAD51 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD51 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
RAD52 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15766559 17145710 9826763 20190268 17118963 10666456 12750383 9837724 19338310 10448035 10212258
S100A9 S100A8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12645005 18802069 18809714 19732719 23248262
S100A9 S100A8 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12645005 18802069 18809714 19732719 23248262
UPF1 SMG1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11544179 11331269 19359157 19417104 16452507 14636577 20817927
SMG1 UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29768215 24115769 11544179 11331269 25535763 25013172 23356578 19417104 21965535 18423202 15175154 23826386
SQSTM1 CUL3 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 14744430 15340068 16252010 18545270 19427028 20531300 21981924 25002027 26587781 28574505
SP1 SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9762895 12736330 17012241
PRKAA1 STK11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 14511394 15579580 8779952 14985505 14614828 11018120
STK11 MARK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 17192257 14676191 14976552
STK11 PRKAA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 16434556 25792737 14985505 14976552 20489196 21062936 20656472 20616029 17255104 16041368 25696921 21399626 12391032 20160076 17244528 15980064 17054914 22517326 14532170 21918180 28694351 18693249 26771234 20801214 16600998 18195011 28723898 16912160 22039048 26068970 14614828 19884317 25679763 22575644 19197243 27864418 30022161 25683918 18303014 17287464 15327994 12764152 16054095 15509864 26506235 14511394 27181208 28625738 25874865 8910387 17276402 26247630 21680840 19414597 23418352 24289924 15383373
VAV1 TLN1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
TLN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19118207 12606711 7716514 3124107 10497223 19118212 21947080 11279249
TP73 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16582625 19861536
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
SP1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1346130 16675542 7905000 12746293
HIF1A CXCR1 â—¼   UP_REGULATES ✅ + 16.0 1.0 ACSN 10804084 16110315 16127144 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824
CDC73 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 16630820 23331499 21726809 18988627 29774127
SYK NCK1 â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
SYK NCK1 â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
SYK NCK1 â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
VAV1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 8900182 7518558 23331499 12573241 8629002 23180781 11331248 11262396 10592173 16189514 10092764 8630736 8986718 29145629 9151714 16546099 8809042 24243840
CUL1 RICTOR â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16469695 16697054 17884153 18931676 19143635 19622404 19686080 19809470 19847258 20832730 26159692
CUL1 RICTOR â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 15703371 16469695 16697054 17884153 18931676 19143635 19622404 19686080 19809470 19847258 20832730 26159692
AKT1 RICTOR â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 RICTOR â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 RICTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 21177249 20338997 19402821 15808505 20138985 21339740 16603397 20214616 21474067 16919458 15718470 19568798 17545609 15169778 18566586 25241761 19720745 18925875 22990118 10949026 11715018 19143635 18636226 18411301 9812896 21343617 17680028 19151919 18566587 10722653 20832730 18570873 17052453 12408816 11274345
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
HIF1A PGK1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A ENO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8955077 15459207
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
HIF1A PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15794924 19828020 8089148 18024476
HIF1A PGK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16585195 8089148 8702901
SP1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9328340 8923463
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
HSPB1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19656944
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12740362 11042204 19593530 22983196 17510053 23397142
AKT1 PRKAA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19376078 16340011 16083285 26506913 27784766 24467442
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23041284 24497960
ARRB2 GNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10508237 23109003 17084806 18538863 10644702 16183910 15337520
PRKAA1 HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27010499 18184930 21892142
CSNK1A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 64.0 1.0 Omnipath 9312064 29495399 14966280 23531534 21764279 26227550 29793495 28220106 20561505 26862734 19293931 19623618 27558955 28430641 11818547 25546293 16199882 24648413 28337019 27672271 11955436 9482734 25915038 20419129 23778311 19244247 25500543 27768599 27488834 28183999 17208333 24594309 24038789 23076981 24904820 23690993 23744610 12000790 23687614 12114015 10488109 26604501 19711366 20699366 25517963 26189775 10023673 22025562
HSPA8 DNAJA4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
CSNK1A1 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16511445 21233202 7641885 11980723 15121840
CSNK1A1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 28695147 17081983 18669648 18691976 20068231 19860830 9360956 16045749 98030561 19664995 19415658
PAFAH1B1 NDEL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17145710 14970193 12796778 11163259 27173435 12885786 10931877 19622634 11163260
KATNB1 KATNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9568719 26929214 10751153 26496610 16203747
KATNA1 KATNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9568719 26929214 10751153 26496610 16203747