Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MYC AIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
ATF2 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20086235 10037779
HIF1A BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17558861 19211554
BCL6 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14654791 11914273
BCL6 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22422878 19487462
HTT CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKT3 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 AKT2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
HTT CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16777606 10770929
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
TEAD1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20153295 22286761
EGFR CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7945309
CHEK2 H2AX â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 H2AX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
HTT CKM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
GRB2 DUT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
FOXN1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20233718 22387311
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
FYN FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FANCA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
JUN FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21460851 20638938
MYC FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20638938 19366810
FLNC GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SNAPC3 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
ASXL1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DDX6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CAMK2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 MAP2K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
MYC PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18809243
MYC HK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17785433
MYC MBL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21559732 11318533
CREB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
MYC TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9988278
TERT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18775701 6742757
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
FAF2 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
VCP FAF2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PGK1 PCNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA ENO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA ALDOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
ATF1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7479004 9883884
CREB1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721872 12658356
PCNA ENO1 â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
PCNA ALDOA â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
LRRK2 DYRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ARNT BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12354771
HTT DES â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DDX6 ALOX15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20884783
ACTB HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
JUN ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10840940 11082319
SRC ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 7296071 19903481
HEY2 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10692439
FOXN1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12845342 9368008
FN1 ITGB1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN FLNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ARNT IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20511231 21104991
CREB1 IL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
NCOR1 PPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NCOR1 CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934400 12072427
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
JUN ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21384344 16786139
JUN ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8382609 22243239
JUN PRKN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20638938 21113145
JUN CYP3A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14742674
PRKN JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20418918
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AB1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A ENO2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020
HIF1A KDM2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
HIF1A ALDOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8089148 8955077
ZP2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731430 11940572
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKT1 ACOT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33148467
HTT CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10698518
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
ATF1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10075672
NDN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R5E HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT AKR1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATF1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10698518
ATF1 MAP1LC3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20514020
SOX2 ATOH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22340499 22292066
SOX2 ATOH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15846349
IRF2 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9625761 9490737
ATF1 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11108136
ATF1 CCDC65 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12527906
EGFR TUBA1A â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
HIF1A HSP90AB1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
COX7B COX8A â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
EP300 ATF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10327051 24069158
CFTR BAG3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CUL4B DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34026424
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
ALDOA EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
FANCA CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23303816 24469828
VCAM1 GRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MYC CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 20551172
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC FAF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
CTBP1 H2AX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 31041561
IKZF1 CUL2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 DDX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
MYCN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
JUN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17056544 25609649
TEAD1 JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 26258633
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 ALDOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 PPIA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SOX2 TEAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
VCAM1 FLNC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 ASNS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
ATP6AP2 ATP6V1E1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
CFTR UBE3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19233847 17110338
FAF2 UBE3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29263404 18775313
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CFTR HSPA4 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CBX5 DNMT3B â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CFTR USP10 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCND1 CUL1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
EGFR CD44 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11606076 16565089 12093135 15597342 23265944
AKT1 FANCA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14499622 11855836
MYCN FBXW7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19111882 27837025
GRB2 PPIA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31980649 12577067
MYC ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11839798 29467282
MYC HIF1A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 15071503 28205554
MYC TERT â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32140074 28628118 28205554
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ATF2 ATF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25609649 26344197 31964530
CUL4B HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618
FBXW7 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 8399454 23108047
SRC GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 11964172 9016807 12624098
CUL1 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
HEY2 HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 11486045
HIF1A JUN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
AKT1 ARNT â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15833858 28628118 28205554
CFTR FAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
CFTR ALDOA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
ERBB2 GRB2 â—¼   RELOCALIZATION ✅ + 0.85 0.85 Signor 14967450
ENO1 SRC â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CUL4B PPIA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
OTUB1 PCNA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26752685 18954305
CREB1 JUN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 2138276 25609649
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
ASXL1 AKT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33758188 18624398
HDAC6 ERBB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20029029 31980649
HEMGN CTBP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 24740910 21988832
BAG3 WBP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 23824909 25036637
NCOR1 BCL6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15454082 16713569 9824158 11865059 10898795 16147992
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
MYC ACACA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 17353931 29467282
PGK1 PCNA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26030842 20849852
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
HIF1A CUL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23401859 27320910 19940151 18323857 17439941 17132228
SOX2 NCOR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 28794006 23667531
CUL3 ARMC5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781 33130828
HIF1A HSPA4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
DDX6 DES â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AIMP2 PARK2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
FN1 ITGB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
EGFR HSPA8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ATP6AP2 ATP6V1A â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
FYN CD44 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 16713569
HEY2 NCOR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11486045 16713569
IKZF1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23752268 16189514 30760870 10357820 12015313 10204490
MAP1B LRRK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24754922 21159966
AKTIP AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 14749367
IKZF1 IKZF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 9155026 26823144 33961781 10204490
FBXW7 JUN â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC1 BCL6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15454082 9627120 9753732 16147992 10611298
CD44 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
CD44 ERBB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11606076 28628118 12093135 17092940 28205554
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
EGFR FGR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
CREB1 EP300 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
AKT1 TERT â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28628118 15843522 28205554 10224060 18775701
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CREB1 ATF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25609649 8384217 1655749 20102225
SGCG FLNC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10629222 14506720
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
DDX6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
DES YES1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AIMP2 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
JUN ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8027667 20102225 28514442 16511568 23661758 15546613 26496610 2320002 20195357 10327051 1827203 9445037 20511396 10207054 25609649 33961781
ATF2 ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1387083 8382609 18385943
ACTB BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CREB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11450946 16205321 18830594
BCL6 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21106671 12594267 15507530
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
PCNA CCND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15681588 7908906 8101826 33961781 7903056 21654808
SOX2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18456656 25482558
BHLHE40 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23423709 21506129 22905217
MYC CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22002305 22911891 19738061
COPS5 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11707426 18926707
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
EGFR HDAC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 24658140 20133936 25402006
EGFR ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500850 25241761 30898150 17486068 11526509 9461599 23866081 17426253 10572067 11500516 24557338 8665853 15657067 19060928 16516204 19650109 20211985 25315821 23436906 21278786 25898135 32669362 1346931 24189400 21044682 18803307 16843263 28369073 7531698 16713569 17148612 21203579 17307140 1706616 16207817 7797556 12354693 11408594
MYCN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
YES1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 22430206 11160627
EP300 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11268218 16713569 18263614 12937166 24939902 14988403 33742100
EP300 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27956703 21268080 21937452 24069158 11689449 14630807 11980644 10327051 12437352 12471036 24636898
EP300 ARNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12573436 10999956
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
FBXW7 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27795300 31569395 35140242 15150404 33494392 15498494 28007894 23750012 31638140 17646408 28209614 16023596 17157259 25716680 20970423 23791182 32021252 30606768 32345600 17873522 33821962 31152129 20848231 32047362 22524983 17314511 25720964 31285543 32350066 33086033 15103331
FN1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18624398 19738201
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
GRB2 IKZF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 32296183 25416956 27107012
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
NDN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26384308 24349431
MYC AKR1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CXCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC ACP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ACHE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18413597 10500217 18414489
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC ALG5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC ACOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC ADCY9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ACADM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PRKN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20638938 15078880 23277542
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
H2AX OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
HDAC1 PCNA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11929879 16189514 16713569 14988403
H2AX ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
HIF1A BHLHE40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020
AKT1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16256741 10896934
SRC ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11723131 11259684
CTBP1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21102443 9650586 16189514 23752268 31041561 16713569 28947780 10995736 34147029 18765668 11022042
HIF1A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17273746 11641274 16511565 21148070 24015760
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
AKT1 NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23940660
JUN VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9468519 16271621
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
HIF1A HK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020 19689405
HIF1A HK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11557773 14672622 16782875
FN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
SRC ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22973453 11940572 17875712 19372587 21075308 29720121 7542762 7797556 19704002
MYCN ACOT4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 IFT88 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
IKZF1 CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IKZF1 CTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21900206 16189514 25416956 16713569 10766745 24722188 27107012
IKZF1 IKZF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17383641
MAP1LC3B DNMT3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TRIM65 UBE3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ATF1 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9603992 10227167 10731689
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TTN TCAP â—¼   PHOSPHORYLATION 0.9 0.9 Signor 9804419
MAX MYCN â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ATP6V0B ATP6V1F â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BAG3 HSPA4 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
BAG3 HSPA8 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
GRB2 ERBB2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 16273093 5218056
ATP6AP2 ATP6V1F â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
FBXW7 MYC â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COX5B CYC1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ATP6V0B ATP6V1A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
FBXW7 JUN â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 14739463 31843895 30044990 29225075 16023596 28036276 33086033 29346117
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ATP6V1A ATP6V1F â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
BCL6 NCOR1 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
ERBB2 GRB2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
CREB1 EP300 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12665587 21268077 10506141 21212407 11313407 7870179 17476304 22787115 26944191 33846793
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
FBXW7 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 28522751 23108047 23322298 28007894 21145461 22388891 29695787 23453757 14603323 22405651 29499133 31285543 25143387 32086376 22524983 11585921 25515538 25720964 26976582 21205095 29103612 33961781 29408378 11565034 32350066
ERBB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9710588 11173924 21278786 16713569 9756944 24189400 31980649 22973453 24658140 30898150 16273093 17875712 16729043 11606575 8665853
HIF1A ARNT â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 17916562 9159130 24434214 20049704 9704006 11606485 27684187 19168635 11829741 23458834 19845609 16861921 9079689 19251694 11593383 27320910 15850782 15833858 20562859 14764593 12391259 26496610 17197389 8663540 15479785 26160453 14668441 24056783 11025203 28205554 23796364 23363003 20458141 23086815 17213817 21620138 15615775 7836384 15319539 12393189 11782478 15347669 20932347 21512126 10085255 21435239 26350169 15031145 20603618 28628118 20699359 10671489 33961781 34592152 16520375 12810720 16954218 18024476
FAF2 VCP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PCNA SPRTN â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
TCAP TTN â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
ATP6V1E1 ATP6V1F â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
MYCN MAX â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 2006410 23792191 26062444 24859015 10229200 1935896 18003922 18488021 27728805 10597290 29028833 25175806 17289033 20946988
CUL1 FBXW7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ATP6V1A ATP6V1E1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PRKN AIMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16714300 27197155 16049031 12783850 16135753
ATF2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
ATF2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9990041 10915780 11850817 11410592 11739785 15691880 16405968 10464245 10500157 15314161 10066798
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
ATF2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21479385 8335091 10471826 8703044 9151819
ATF2 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16452470 12196528 15663480 17896792
MAPK13 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 9207191 10581204 15140942 20506250 21614932 19135240 16393692 12244047 11274345
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
BAG3 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 25036637 27474740 23824909 21233200 9873016 26496610 16189514 21423662
MYC BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14517295 18802399 16316993 17331788
AKT1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
NCOR1 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15454082 16147992 9824158 16713569 10898795 11865059
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
HIF1A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23455892 20360945 20179204 15991006
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CTBP1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
MAX CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CD44 SLC9A1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 16104017 9712871 15090545 8901634 11350981 17050540 15035633
FN1 CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1730778
H2AFX CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
COPS5 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25609649 20093369 18926707 10766246 16713569 8837781
PCNA CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
FGR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31980649 24658140 11160627 25402006
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 21220489 24655521 23542172 29140271 28157503 26725162 22238610 25825764 17115032 26719139 28102297 22692198 28666590 25073158 20670598 20587074 23593472 25675097
AKT2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17964260 16926151
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
FBXW7 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14739463 28036276 18930588 16023596
FBXW7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15498494 17145710 32047362 28007894 31569395 33821962 20399964 20970423 17157259 16023596 20852628 15103331 15150404
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
GRB2 ITGB1 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
ERBB2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 31980649 9756944 21278786 16273093 24189400 11173924 9710588 24658140 11606575 14967450 17875712 16713569 16729043
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 16596619 21988832 10229200 17471507 26267534 15572685 18003922 20382893 35140242 17418410 25609649 16352593 31767764 17072308 17289033 10918583 9528857 14749374 21807113 19623651 18620061 25522242 32296183 16140957 16705173 19578763 26496610 12584560 17157259 17643117 24951594 20946988 10465786 12706874 12821782 9184233 17353931 10611234 32140074 8266081 20691906 16410719 21150319 10593926 12660246 27859590 12553908 8224841 10319872 2006410 16287840 16606833 23816886 9708738 17314511 9886493 27705803 33298911 33961781 20936779 12824180 9680483 17700062 29467282 30415952 12391307
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
MYC ALOX15 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
MYC FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14519204 11896591 8376401 10421838
MYC ITGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11381265 16878156 12695333
MYC TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 76.0 1.0 Omnipath 16287840 15655249 12821782 16880523 21807113 19047367 14744757 16489011 12941894 10786671 14519204 19360348 10723141 12970752 15595642 18365874 15665468 22207128 14611815 10022128 15226182 11274400 10491298 11606399 17070091 19787269 19806010 20454512 19762557 21132266 21553143 18818322 10914736 17934056 19148473 11435602 12695333 12802280 21995449 11287602 12044867 21627565 23860446 17942561 19649288 23759068 10606235 12807729 15958520 17141225 20723213 16402390 16785237 18093727 21855630 24705139 18367227 14563552 16205635 19003324 9988278 17706770 17967894 18226852 18754863 10637317 18586674 14612409 19912441 15371341 11916966 12646176 11279234 18158869
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
HIF1A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18754863 15048086 17699105 16961934
AKT1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 25999477 22366458 10224060 17570479 22902867 15843522 18775701
SRC TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12808100 20211239 24413564 26908447 18829466
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
AKT1 VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16551632 19335618 16027165
PCNA CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA H2AFX â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
PCNA H2AFX â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 11756412 11850621 11877377 11927554 12239151 12551922 12607003 14624239 14726013 15459660 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18809224 18931676 19075014 19217432 19264559 19622404 19686080 1974050 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20723763 21060331 21337561 21376743 21574959 22021614 22101340 22743550 22751496 22771115 23414611 23444773 24050180 9488723
JUN PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22550165 19940138 1352831 15205327 23078099
DYRK2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20831597 22307329
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
CUL2 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
ITGB1 FN1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
VCAM1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12097820 22623428 19738201 19057841 11751331
FN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9842903 22451694 17015452 18480047 19738201 7688313 1694173 6325925 25237190 26456826 10772816 7626807 21985969 6284125 1532572 11010812 8120056
PLG ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15247268
FN1 FYN â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
HIF1A IL6 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10804084 15749903 16110315 16127144 16243976 16413922 17485448 17533374 20427344 20535745 20855962 21051947 21765015 22006996 22850421 22988108 24006507 25043024 25103413 25732824 9743347
HIF1A IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17548584 20003295 21258402 15913932 18791496
JUN IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 26513016 10542237 21069809 15389813 15158360 20225236 12667961 20371366 20511231 20862675 8453101 10202034 18502099 10037779 8830832 19687301 21098092 25567680 20351184 17341596 11120852 21312239 24676671
CREB1 IL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8725624 19342597 20100571 20160059 11701462 16424113 18617614 19162127 15467434 21209948 23874122 17495236
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
MAPK13 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
JUN FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24342046 21479385 11052809 9756884 23744703 10325245 11896591 10421838
JUN SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7499226 16798740 23533633 14736735 18216279
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 WEE1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
ARNT HIF1A â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
HIF1A ALDOA â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A HK2 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A PGK1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A ENO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8955077 15459207
HIF1A TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10849669 21835053 20043814 18465225 20143408
HIF1A ALDOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8089148 8955077 9748288
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
HIF1A PGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15794924 19828020 8089148 18024476
HIF1A HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15794924 14726529 20068160 18844219 18683594
ARNT HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17213817 8816435 17197389 14764593 12393189 12810720 15319539 23363003 9079689 11829741 15479785 26496610 12391259 17916562 24434214 11606485 20562859 9704006 21620138 11782478 20932347 15347669 8927054 21435239 19168635 9159130 14668441 20049704 20603618
HIF1A PGK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16585195 8089148 8702901
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
PRKCI SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 11713277 15567848 14585353
SRC HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17855507
SRC ENO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8578591 7629021 15592455 15951569 96108162 15212693 24841372
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
AKT1 HK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 29985480 31435020
AKT1 SLC9A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20026127 16475831 18757828 10400637 33655882
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11175347 11756412 12356771 15733869 20452955 20398329 11160957 10217147 19216069 20214616 11463845 9829964 7958915 12235136 16680151 17646672 9687510 8887554 11698596 8688081 17680028 9528766 11018520 11969286 12519783 11909979 15725726
CREB1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 2170405 22357921 8648265 15908479 1845987 8803927 2542772 15608673 1404598 1320003 12372774
CREB1 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16893419 10407170 15240392 20367754 11238722 16452470 9645965 11108136 9038229
AKT2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
AKT3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 17646672 10217147
CAMK2D CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11175347 12356771 15733869 22554507 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
RPS6KA4 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 11175347 12356771 15733869 11160957 23331499 9792677 9829964 7958915 12235136 9687510 17158541 15187187 18813292 17668895 8887554 11698596 8688081 9528766 11018520 11969286 11909979
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
ARNT CYP1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9374477 17023418 22387692 19376845 17012224 12369894 19287966 8631128 15832810 9717460 19255421 8647831 12376470 16111650
TTN TCAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 15582318 11846417 16407954 15802564 9804419 9817758 16962094 19622741 16713569 12446666 23414517 9645487
RPS6KA4 ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23331499 8384217 18813292 18690222 8663317 20068231 11018520 11335727 9687510 20626350 11909979 9016641 12414794
MAPK13 RPS6KA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15187187 19436832 15140942 20506250 21614932 16393692 11274345