Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CCT3 EED â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC CCT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
ATXN3 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SEC24B CD74 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11790530 2391366
TFDP1 CD74 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1297652 10778981
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
COPS6 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
HSP90AB1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DNAJA1 STIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DNAJA2 HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
TTC5 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18451878 6743367
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
HSPD1 ACTR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPD1 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPD1 FADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPD1 OGT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
HSPD1 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8676499 16713569
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214648 11588219
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
ATXN10 MYC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC STIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC PDGFRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15226411 18697203
MYC CD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1321339 11266125
MYC HLA-DRB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17881904 18544564
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
E2F6 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12004135
MYC TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11139609
MYC TFRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
CDC42 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
RBBP4 RPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TPT1 ATP1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218698 16730713
HSPB1 TUBB6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16525503 5218414
VCP FAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18711132 0805371105
FAF2 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
UBXN6 VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
VCP FAF2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
VCP UBXN6 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
USP11 CBX7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
TUBA1C VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
ATXN10 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VIM TUBA1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CTNNB1 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22552774 12750294
DUSP16 GABARAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDGFRB CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10733900 6731185
CRK SUV39H2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK ARHGEF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PDGFRB BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9546424 9739761
LCK DLG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221707 9341123
CD4 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
LCK PTPRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6672875 7507203
TUBA4A BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA5 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
RHOA NCL â—¼   COLOCALIZATION 2.0 0.8 intact 21281639 8086571
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
AHNAK LRRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LRRK2 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
CDC42 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704645 14724572
ALYREF AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18562279 0802533105
TUBB IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TIMM50 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PTPRC CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12370829 6671521
HDAC6 TUBA4A â—¼   COLOCALIZATION 2.0 0.8 intact 5215415 12024216
HDAC6 TUBA4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024216
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
PALS1 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKN ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20940148 18599482
EEF1A1 PTPRCAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRKCE TJP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23967087 24727247
GSK3B CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219694 17318191
TUBG1 GSK3B â—¼   COLOCALIZATION 2.0 0.8 intact 17139249 5219394
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
FRMD5 CTNNB1 â—¼   COLOCALIZATION 2.0 0.8 intact 22846708 8385346
PRKN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20418918
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
DLG1 MAP2K2 â—¼   COLOCALIZATION 2.0 0.8 intact 21615688 8182979
MAP2K2 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
HSPA5 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 15146195
NR3C1 FBXO32 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18615595 19059383
NR3C1 CPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9774647 10562461
STIP1 RBBP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
E2F6 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 12909625
AFG3L2 PHC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PHC2 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PHC2 PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CBX4 USP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
E2F6 PCGF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11171983 5213507
USP11 PCGF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
ATXN10 PHF19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHF19 SUV39H2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
E2F6 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
PRNP STIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12093732 16713569
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
MDM2 CDKN2A â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 7989562 20713054
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
CBX4 PCGF2 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
JARID2 PHF19 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
MDM2 CUL4B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28225217 22032989
CUL4B RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23238014 34026424
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
CTBP1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21102443 15834423 35016035 16122695
TTC5 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18451878 11511361
MYC RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 20551172
MYC PHF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
MYC ASPM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC FAF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC NEK9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
PAK1 ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16452229 12374744
ESR1 RCN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
PGAM5 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 17046835
LRRK2 RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 21454543
LRRK2 HSPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24725412 29519959
LRRK2 TPR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
STIP1 CFTR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20534503 31324722
CFTR HAX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
CFTR RCN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
LCOR RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
PHF19 RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23104054 27705803
PHC2 PCGF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 24981860
PCGF3 PHC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 24981860
E2F6 PCGF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11171983 24981860
LCOR PHF19 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
DNAI2 STIP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HSP90AB1 NR3C1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
TUBA1A TUBA4A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CBX7 PCGF2 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
MYC HSPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
PHF19 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23104054 27705803 33961781
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
ESR1 ACTN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23403292 21182205 19805454 31527615
PHC3 CBX6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 33961781 27705803 24981860
CBX6 PHC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21282530 27705803 22325352 33961781 24981860
PCGF3 CBX4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 27705803
PHC1 PHC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22325352 33961781 24981860
CD74 CTSL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MDM2 NCL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
TUBA1A TUBB â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
DNAJA2 STIP1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
PSMC5 VCP â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
ASPM RCN2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28436967 26496610
LRRK2 STIP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31046837 24510904
CBX6 PCGF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21282530 24981860
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CBX7 PHC3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
GSK3B CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 16293724
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ESR1 RBBP7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18577416 23403292 21182205 31527615
CFTR RCN2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
CFTR RPN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
CUL1 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
PCGF3 CBX7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 21282530 33961781 26186194
PTPRC LCK â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7507203 6672875
BCAR1 LCK â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9020138
PTPRC LCK â—¼   PHOSPHORYLATION ✅ 0.85 0.85 mint 7507203 6672875
PTPRC LCK â—¼   DEPHOSPHORYLATION ✅ 0.85 0.85 mint 10369126 8310409
LCK PTPRC â—¼   DEPHOSPHORYLATION ✅ 0.85 0.85 mint 7507203 6672875
ESR1 MYH9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21182205 19805454 25604459
CFTR MYH9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22038833 29924966 26618866
LRRK2 CDC42 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
CFTR FAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26618866 31324722 29924966
CFTR HSPB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 26627832 17110338 29924966 26618866 23155000
CBX6 PHC3 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
TUBA4A TUBB â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
MDM2 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20708156 24804778
CRK HSPB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22939629 31980649
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
CUL3 NUP50 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
ASXL1 AKT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33758188 18624398
HSP90AB1 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CBX4 PHC3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
MYC RPN1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 35140242 29467282
AKT1 PAK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24886428 23397142 14749719 12138087
BAP1 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32509391 19615732 34591877 29686263
RBBP7 EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194 12435631
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
PHC1 CBX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803 24981860
CBX7 PHC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21282530 19636380 27705803 33961781 24981860 26186194
CBX7 PHC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 24981860 26186194
RHOA ARHGEF11 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 7909059 20300064
PHF19 EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23104054 27705803 26496610 33961781 24981860 21143197
LCOR EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 27705803
PHC1 CBX6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
PHF6 RBBP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25601084 22720776
PHC2 CBX4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21282530 27705803 26496610 22325352 24981860
PCGF2 CBX4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21282530 20601937 19636380 27705803 22325352 33961781 24981860
CBX4 PHC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21282530 27705803 26496610 22325352 24981860
PCGF2 PHC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20601937 19636380 27705803 22325352 33961781 24981860
CBX4 CTBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ASXL1 BAP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ARRB1 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TUBA1B TUBA1C â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PHC1 PHC2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CUL4A NEDD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16503656 19617556 22474075 18274552 31973889 24654937 16620772 12481031 19295130 23201271 16964240 10597293 21145461 18247557
RNF5 CFTR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21594788 16901789 19269966
FADD TNFRSF10B â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
ADRB1 ARRB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10862778 18787115
CBX6 PCGF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 21282530 27705803 33961781 24981860
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CBX4 PHC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
LCK PTPRC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CBX7 PHC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
MDM2 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12897156 11178989 16713569 10766163 17545634 31012223
MYC GSK3B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16247449 11877389 14563837 20713710 19131971 21150319 31638140 8247524 29467282 33541412
CBX7 PCGF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21282530 20601937 33664452 19636380 27705803 33961781
RHOA PKN3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31871319 33961781
DLG1 LCK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25241761 9341123
AKT1 HSPB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17510053 31980649 12740362 11042204 23397142
CTBP1 LCOR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31041561 20211142 12535528 27705803 33961781 35016035 26186194 24722188
PCGF2 PHC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 20601937 33664452 19636380 27705803 22325352 33961781 24981860 23523425
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
JARID2 RBBP4 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
METTL3 WTAP â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
KRAS CCT7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CCT7 DNM2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
COPS5 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18926707 17879958
MAPK6 COPS6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
EP300 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15154850 20234175 16713569 11070080 9809062 28196907 15013777
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
MDM2 ARRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17984062 15878855 32450252 26545496 12488444 11588219 21988832 21466165 33649538 21389118 18544533 21081496 32828283 12538596
GSK3B MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16055726 18505846
MYC RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC ELK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC THBS4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC PRKN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20638938 15078880 23277542
MYC GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22159222 20383141 22235332
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
KRAS PAK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15520807 17462920 20363321
RBBP4 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17255935 27705803 22863883 33961781 24981860 26186194 15451426 22939629 26344197
RCN2 GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
CUL4A CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 21249194 22474075 12504025 15448697 18606781 31973889 12609982 27203177 12504026 19295130 16964240 21145461 22405651
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
RNF5 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16901789 17145710 21148293
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
VIM GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TNFRSF10B FADD â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12721308 17327223 10894160
LCK PTPRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9533446 24463463 19167335 15085197 8576115 8473339 7507203 14625311 10369126
NR3C1 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16888650
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
ESR1 SEC61B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
RHOA KIF14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
ARHGEF11 RHOA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
AKT1 GSK3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19713527 8524413 23824745 16009706 29464284 20856200 19995607 16123141 20682768 27563096 14645548 15688030 22337773 11035810 17428466 18505846 15470047 14701753 16282323
MAPK6 TUBA1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TUBA1A GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBXN6 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KRAS EEF1A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EEF1A1 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 STX7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STIP1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21170051 27353360
ESR1 CCT6B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
EED MAP1LC3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EED CTSL â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
PHGDH MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PHC2 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
E2F6 RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909625
CBX4 CTBP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15592428 20098713 33961781 20361981 12679040 26186194 11583618 9858600 12829790
BAP1 ASXL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 20805357 29284740 34591877 27705803 32669118 33961781 26186194 19815555 26416890 33731362 19615732
BAP1 ASXL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26437366 22897849 20805357 21642991 34591877 27705803 32669118 33758188 32683582 20436459 19815555 26416890 34170818 33961781 23850490 19615732 26739236
PHC1 PHC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 16713569 22325352 33961781 15563468 24981860 9121482
PHC1 CBX4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21282530 22078878 9199346 26496610 27705803 22325352 33961781 24981860
E2F6 TFDP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 25416956 9501179 20211142 9704927 27705803 33961781 24981860 26186194 26871637 15536069
PCGF2 PHC2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PCGF2 PHC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PHF19 RBBP4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
PCGF2 PHC3 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
CBX4 PHC1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
CDKN2A MDM2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ARHGEF11 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 32203420
TUBA4A TUBB3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
PSMA4 VCP â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CBX7 PHC2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CAND1 CUL4A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
AKT1 ARRB2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 18191226 19122674 19262695
EED RBBP7 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
BCAR1 CRK â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
EED PHF19 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CCT6B CCT8 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
RPN1 SEC61B â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CCT6B CCT7 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
E2F6 TFDP1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PAK1 CDC42 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5220560 7744004
AKT1 STK4 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 19940129 17932490
CBX6 PHC2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RHOA TUBA4A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TUBA1A TUBA1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CCT2 CCT6B â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
PHF6 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RPGR TUBG1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
TFDP1 E2F6 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
IQCB1 RPGR â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
UBXN6 VCP â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
AKT1 MDM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32450252 25241761 18332867 12145204 19166854 15527798 20856200 11715018 23397142 11504915 11923280 21930127
MDM2 ARRB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 15878855 11588219 21466165 21857681 18544533 21081496 29676828 12538596 19879840
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
CD4 LCK â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17653867 16888650 16189514 15047060 11854499 12007789 8104794 8246987 17005671
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
PCGF2 PHC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 25416956 31093962 20601937 19636380 27705803 22325352 33961781 24981860
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
PAK1 CDC42 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9535855 11157984 21029865 16678097 19596003 23455922 9705280 31871319 25150978 12879077 12606577 10360579 31478661 10684602 8107774 21048135 23175184 18057010 10802735 21167153 15548653 12650940 18426980 7744004 20936779 24276241
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
CTNNB1 GSK3B â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
EED RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15225548 29379173 21078963 27705803 26496610 33961781 24981860 12435631 15385962
CCT3 CCT6B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
FAF2 VCP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EED RBBP4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CCT4 CCT6B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CCT6B TCP1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HSP90AB1 STIP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CD4 LCK â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
ARHGEF11 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
EED JARID2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ATXN3 VCP â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CCT5 CCT6B â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CRK BCAR1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31980649 9581808 22974441 15673687 10208419 12615911 10464310 15492270 12799422 18835194 8631823 10747099 11278916 16413489 10753828 16267043 10329689 19380743 10085298 14657239 27669437 17038317 9920935 11369773 11839772
ASXL2 BAP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CDC42 PARD6B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA4 PSMC5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC42 PAK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CD74 DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
IKBKB CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21619050 20152798 29292732
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
CDKN2A MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 12167711 18541670 23416275 9529249 17426254 12630860 17116689 12085228 15856024 10822382 19166854 12209154 12740913 17158541 16915296 17909018 25809483 9653180 14612427 22120712 16173922 10871849 18418067 24769896 9724636 21133853 10801444 19049976 9529248 16107876 18813780 20713054 18467333 15355988 18583933 20395212 11223036
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
AKT1 COPS6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26318036 23095642
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
PPM1D MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18265945 17936559 17939684
ARRB1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15878855 23331499 21081496 12538596 17303558 11588219 21466165 18544533 21857681 19879840
NCL MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 24147044 16751805 22103682 20195357
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
NCBP2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
MYC SLC1A5 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 19033189 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
MYC TFRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 3302722 12695333 14519204 16466700 20631077
MYC NCL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10606642 24951594 12695333 14519204 25018006 11983916
GSK3B MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 73.0 1.0 Omnipath 17081983 18463697 21646472 30037819 26751215 25647305 2663470 20080742 19797085 30003124 16855632 12040186 18679417 11018017 23331499 29229669 16611981 21071413 24265759 20068231 10671551 16039586 17570479 16023596 29258530 12615961 18669648 21113395 22461507 19131971 8247524 16247449 20604938 19575820 15150404 22481935 23668310 19651622 17444818 23964270 20537194 22893788 27684546 24662831 25333250 20399964 11877389 14563837 18408012 17052453 18455992 15212693 16371461 11274345
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
MYC GCN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20936779 17353931 17314511 17093053
PAK1 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21372320 21177870 18720373 21317288 18248330 17161475
PAK1 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10661401 11062502 11385609 11907067 12885870 14764585 15536084
AKT1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11435472 14749719 24886428 14585966 23397142 9032240 12138087
CDC42 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 810774 10360579 21167153 8107774 10559936 9705280 12650940 16678097 23331499 21029865 10684602 18057010 15020669 21070974 11340065 21048135 15003621 20936779 10934474 11413130 15788770 15713627 9535855 23109003 11950587 19628037 7744004 12879077 12606577 24276241 10224076 19596003 8973630 19812368 11248548 10802735 18719708 10613909 10461188 23455922
PAK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18521086 26944939 16778166 18755239 21893191 15178330 19205871 29548483 26554417 27003261 24505617 16452229 15193262 19557173 15642175 12374744 19465939 17604944 25447917 20179234
PAK1 NF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17081983 14580336 21481793 23162742 22105362 18071304 20068231 19036346 18669648 20302846 15378014 27285107 28090172 27345717 19165420 14981079 26555075 19651622 19691289 22567403 11719502 25893302 11782491
PAK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 14722118 11895474 17081983 16565220 26369929 28390425 27457922 11420699 15713670 15766329 7983050 12458200 12761892 26956613 16964243 28096473 15345747
PAK1 ACTR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16293614 10467124 14749719 9843499 16702231 10511705 12054568 8625410
PAK1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 28007610 12872159 16999872 18354494 20361981 23291169
PAK1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 28007610 28423670 23543898 25639486 26547035 22369945 23162742 25472536 21822311 25225063 27713506 27910850
PAK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7592586 11304531 15677464 11309380 14970210
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
AKT1 VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16551632 19335618 16027165
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
CAND1 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 18606781 19295130 22405651 27203177 17079684 21249194 19231300 12504026 21145461 12504025 22474075 12609982 16964240 15448697
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
TNFRSF10B FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11376335 15173180 9430228 12721308 10894160 14585074 16189514 9430227 15452120
CRK BCAR1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11146654 11353765 12094222 12432077 14697347 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 9808620
CRK BCAR1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11146654 11353765 12094222 12432077 14697347 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 9808620
PDGFRB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 19426560 10733900 16713569 27686861
BCAR1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 9920935 11369773 11278916 15673687 8662907 9581808 8631823 8070403 10747099 12065577 10329689 16267043 10592173 10208419 17038317 18835194 20627867 16413489 10753828 8943292 9860979 11839772 14657239 12799422 19380743 15492270 10085298 12615911
LCK CD4 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK CD4 â—¼   PROTEIN_INTERACTION 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK PTPRC â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10652356 12414720 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 23886063 25312647 3263576 8478617 8986721 9438848 9738502 9751747
CD4 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16888650 8104794 11854499 8246987 3262426 12601806 17653867 23109003 12007789 16189514 17005671 15489916 15047060
PTPRC LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 17145710 19167335 8433999 2141684 9973453 8473339 2141630 12589038 8663450 15085197 2548204 8441403 11259588 15743820 10330160 2530588 10369126 8576115 7507203 11369760 17719247
LCK ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9500442 10571988 25386784 11145737 7539106 27748765
MYH9 ACTR3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
THBS2 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14699013
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
KRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KSR1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 17145710 19541618 27086506 17613518 11909642
ARHGEF11 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 21988832 32203420 20300064 15530360 10526156
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
CDC42 PARD6B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 20936779 10934474 14676191 25416956 23439680 11260256 32296183
CD4 PTPRC â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 PTPRC â—¼   DEPHOSPHORYLATION ✅ 5.0 1.0 Reactome 20346773 23580664 11827988 21543337 2530588
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12740362 11042204 19593530 22983196 17510053 23397142
AKT1 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27997540 24291004
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
AKT1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22619175 19369195 19737514 19940129 17932490 23431053 11805089 24872389 23893242 17726016
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15184909 25241761 22689577 15856005 10485711 17660512
AKT1 ALYREF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18562279
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
PRKCE IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10823818 20448038 17595324 21673972 16267042 20068038 24290981 14514672 27585591 24386391 11325957 23123196 10195894 16735506 25486864 24833394 18266467 10022904 17975552 26195767 20450893 18930133 11460167 9346484 26998110
GSK3B ATXN3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 30283301 28408866 17434145 21900206
GSK3B PRKCE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20350291 34143863 18604201
GSK3B NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30250038 18838540
GSK3B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 183.0 1.0 Omnipath 22415718 11967263 27158593 29455668 19303846 19797085 8638126 19293931 23056571 22662165 25352148 16611981 27068260 28337019 10671551 21743491 20688898 16293724 23721711 23552738 18687691 28977889 19622173 12051714 25241761 27683053 28549350 22699938 19565571 23076981 21562161 19575820 20219694 20537194 10330181 21986938 29183346 27773936 11251183 19711366 21035499 19675674 7542250 23151663 24451375 14663202 23804296 8524413 25639486 23770025 18070361 26892600 30143633 9233789 19667122 27507058 19061640 19223551 29387014 23331499 16199882 11533658 18644116 24501426 24913829 11835406 17318191 26014148 25366337 28183999 22640743 26910375 12000790 12114015 18387957 19107203 9832503 16371461 29805709 27462866 20137080 27902311 12040186 19576224 25644994 12615961 19060929 25897075 12851486 15465828 17053159 18952601 10228155 15020233 17444818 20140245 26453498 17052453 16944320 24015932 23602568 24975844 24931005 28948000 20080742 23209942 30271168 28220106 16520547 28430641 11818547 25546293 27672271 11955436 11154277 26373837 16039586 23778311 28697793 20302655 25136145 26905812 22216350 8666229 12957350 23109003 10074433 28529629 20215423 21329734 11254732 9501208 27098453 27281614 30279527 19631635 25482131 18455992 24403311 11274345
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
KRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NCBP2 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP2 WTAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863