Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CTTNBP2 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STRN4 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CTTNBP2 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT3 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT3 RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216198 12620389
CCT3 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT3 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT3 EED â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC CCT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
STRN4 CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
YWHAZ CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CCT4 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT4 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT4 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STK24 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
ATXN1 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STRN4 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CTTNBP2 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT5 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT5 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ATXN1 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MOB4 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CTAGE1 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STRN4 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PRKACA CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGFBR2 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN3 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STK24 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CTTNBP2 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A SENP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A IP6K2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT6A BRK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT6A KMT2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A SECISBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A PRDM9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A ANAPC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A CCDC30 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT6A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT6A FARS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT6A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT6A YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
STRN3 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
YWHAZ CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
STK24 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT7 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT7 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CTTNBP2 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT8 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT8 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT8 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
MYC TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
MYC PTPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12747840
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
PFDN2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFDN5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFDN5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PFDN6 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SUPT16H APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGFBR2 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 LOXL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
HTT TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BBS10 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
TCP1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TCP1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TCP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TCP1 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VBP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16525503 5218414
DDX20 WRAP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21072240 1000521
GABARAPL2 MLX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PPP2CB IGBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 27880917
PFDN4 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PDK1 TSSK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16336268
GABARAP HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
CDK5 ACTR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTR3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN SUV39H2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN3 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TGFBR2 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
PPP2CA SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20704570 23331499
MAP3K1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10085121
APP RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
PPP1CA HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17008050
L3MBTL2 HDAC3 â—¼   COLOCALIZATION 2.0 0.8 intact 7719892 20385135
CDC20 ANAPC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10318877 12956947
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDH1 POC1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB2B MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 MAP3K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15556606 5217326
MAP3K1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23109003 15032589
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
ATXN1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKT1 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15539407 20606012
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
CDK5 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ TUBA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1B YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TUBA1B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
GNB2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POC1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCAF7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BRK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SECISBP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DDX20 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RYBP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CCNC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKN ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20940148 18599482
POC1A ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R2A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R2B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DUSP6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP1LC3B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP2K2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR2 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15040833 16675543
PPP2CB CTTNBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R2A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1328247 19114990
STK24 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2CA CTTNBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2CA MAP3K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20448038
PRKACA ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20713600
MAP3K3 MAP2K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
DUSP6 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18632752
STK24 CTTNBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CTTNBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP1CA MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP2K2 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
U2AF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RYBP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216393 12757707
WDR83 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKN ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5216393 12757707
RYBP BRK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAZ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB2B MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STRN4 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
KLHDC2 STRN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAZ CDK18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PIK3R4 TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
WDR77 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CCT8 PFDN6 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CCT8 PFDN4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CCT4 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT5 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT6A PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
CCT7 PFDN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
PFDN2 TCP1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
PPP2CA PPP4C â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
ITGA4 YWHAZ â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
CCT2 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT3 CDC20 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT3 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT4 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT5 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT6A VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT7 VBP1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT7 CDC20 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CCT2 PFDN4 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT2 PFDN2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT3 PFDN2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT3 PFDN6 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT3 PFDN4 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT4 PFDN6 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT4 PFDN4 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT5 PFDN6 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT5 PFDN4 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT6A PFDN4 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT6A PFDN6 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT7 PFDN4 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT7 PFDN6 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT2 PFDN6 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
DCAF7 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35016035 31753913
MYC U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC TTC27 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
RFWD2 PARP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25117710 33961781
TBL1Y HDAC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PCGF6 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 12167161
BMI1 PCGF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22493164 24981860
ESR1 RAP2C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
DOCK5 MKS1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
TCP1 VBP1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
CDC20 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 16319895
MYC PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 30415952 29467282
WDR5 SOX2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30089852 35140242 29383478
RAF1 LCK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 8939988
HDAC1 KDM5A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33961781 26496610
GAN CUL3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 15983046 31944090
DCAF7 PCGF5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
ARAF YWHAZ â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
PPP1CA RRP1B â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
FBXW4 TXNDC9 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
ATXN1 YWHAZ â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12757707 5216393
YWHAZ ATXN1 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 12757707 5216393
CCT8 CDC20 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PFDN4 TCP1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
PFDN6 TCP1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CCT6A CDC20 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CCT8 PFDN5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MYC HDAC3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23079660 31155734 22002311 18483244
SMAD2 HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10199400 11226163 31130994 14699069
SMAD2 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20207742 11555647
HDAC3 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29523594 20026773
BMI1 EED â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23238014 24457600
PDK4 PDK3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
PCGF6 WDR5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CCT4 CDC20 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CCT7 IGBP1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CDC20 FZR1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
PFDN4 VBP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
AKT1 SMAD2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16362038 24412244
HDAC3 ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31527615 16469706 14722073 26487511 20348541
PEX14 PEX7 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
CCT2 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT3 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT4 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT5 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT6A PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT7 PFDN5 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
PFDN5 TCP1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CCT2 CDC20 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ARAF RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31980649 34017080 20130576
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
MYC DDX20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
MYC WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 27320920 35140242 29467282 31767764 30415952
PCGF6 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860 26186194
HDAC1 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 27705803 33961781 26186194 33022573 22689669
ILK RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23455922 26496610 25852190
PCGF6 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22325352 33961781 27705803
HDAC1 VHL â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
SOX2 HDAC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 23667531
PDK1 PDK3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 33961781 26186194 29568061
STRN ESR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 15569929
LCOR EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 27705803
PEX14 PEX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 10212238
DCAF7 PCGF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803 24981860
MKS1 B9D1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27173435 32726168 26638075
IKBKE TBK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FYCO1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDC20 PPP2CA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MYC PFDN5 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
VBP1 VHL â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RFWD2 TRIB3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PDK1 PDK3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TUBA1B TUBA1C â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
YWHAZ ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8009399 19933840
EP300 SMAD2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11371641 21988832 10199400 12237408 11264182 15623506
IRAK1 IRF7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21903422 15767370
SOCS1 FYN â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10022833 16713569 29991678
HDAC5 HDAC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10869435 10220385 11466315 11931768 11804585 21081666
ILK AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 12149249 9736715 12176337 11445557 18339839 11825911 11313365 14500673 11278835 11546794
AKT1 PDK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 27166089 27505672 34278744
PPP2R2A PPP2R2D â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
L3MBTL2 RYBP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAP3K1 MAPK8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PPP2CA PPP2R2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PCGF5 RYBP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PCGF3 RYBP â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RYBP WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 26186194
HCFC2 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27705803 33961781 24981860 26186194 15199122
RFWD2 TRIB3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21572435 25117710 30692133 33961781 26186194 32707033 31125554
TYK2 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9196040 16189514 16713569
RAF1 FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 16189514 7517401
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
KDM5A ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11358960 31527615
ESR1 CCNC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
PCGF3 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 24981860 26186194
PCGF6 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 24981860 26186194
PCGF5 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 24981860 26186194
DCAF7 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 33961781 24981860
L3MBTL2 PCGF6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
FARS2 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MYC BLK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
SMAD2 MYC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11804592 28628118 28205554
MYC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 9315742 28628118 28205554
MYC HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 18271930 34147029 26496610 30415952 18003922 22286234 24951594
MYC TUBG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC PFDN6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC IMPA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PRKN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20638938 15078880 23277542
MYC PEX14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
YWHAZ GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DYNC2I2 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LCK RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7935389 8939988 16189514
LCK JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278738 17570479 16189514
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
FYN TUBA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7678277 11826099
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
RAF1 PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 502464200 8203796 16239230
AKT1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 28628118 10576742 19197339 19058874 28205554
RAF1 PPP2CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 502464200 8203796 16239230
PPP1CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7604263 16630891
PPP2R2A RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664191 23331499 16239230
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
TNK2 AKT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652228 11394904 18470881
CDK5 PPP1CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 010002200 11320080 8286802
SOCS1 JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 27144517 11133764 21508344
MAPK6 TUBA1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STRN PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29802198 10681496 18782753
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
EED MAP1LC3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 BBS10 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 HDAC11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STK24 STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17353931 26496610 33961781 24255178 32707033 23455922 18782753
STRN STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 22939629 18782753
STRN STRN4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 18782753
STK24 STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 17353931 26496610 33961781 24255178 24366813 23455922 18782753
STRN3 STRN4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 22863883 33961781 24255178 24366813 18782753
STK24 STRN4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 17353931 23455922 18782753
PEX14 PEX7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 15798189 10212238
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
IGBP1 PPP4C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PPP2R2A PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711181 8288198
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PPP2CB PPP4C â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
TUBA1A TUBB2B â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CCT2 MOB4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT5 MOB4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT6A MOB4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT7 MOB4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT8 MOB4 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MOB4 TCP1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CCT2 STK24 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CCT3 STK24 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CCT4 STK24 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CCT5 STK24 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CCT6A STK24 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
STK24 TCP1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
PPP2CB PPP2R2B â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CCT6A STRN4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CCT6A CTTNBP2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
CCT3 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CCT4 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CCT5 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CCT7 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CCT8 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
STRN4 TCP1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CTTNBP2 STRN4 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
HDAC3 HDAC5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CCT2 STRN4 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CCT7 STK24 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
CTTNBP2 TCP1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
AKT1 ARRB2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 18191226 19122674 19262695
CCT2 CTTNBP2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCT3 CTTNBP2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCT5 CTTNBP2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCT8 CTTNBP2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CTTNBP2 PPP2CA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CCT8 STK24 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
HCFC2 WDR5 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
TUBA1B TUBB2B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
ARAF MAP2K2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PPP4C IGBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 27880917
BBS10 CCT6A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
BBS10 CCT4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BBS10 CCT7 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BBS10 CCT8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TUBA1A TUBA1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
WDR5 KMT2A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
PPP2CA IGBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8434208 23892082
BBS10 CCT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BBS10 CCT3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PPP2CB PPP2R2D â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
MAP2K2 RAF1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
TRIB3 AKT1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 30071535 12791994 31844113
YWHAZ RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 14688280 309620200 8006563
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
TUBA1B TUBB2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
EED HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10581039 11124122 26496610 22439931
ATXN3 VCP â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MAP2K5 MAP3K3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RAF1 YWHAZ â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
KMT2A WDR5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TUBA1A TUBB2A â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
IGBP1 PPP6C â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CCT3 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT3 MOB4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT4 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT5 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT6A PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT6A STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT6A STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT7 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT7 PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2CA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2CB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN TCP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTTNBP2 MOB4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN3 STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT2 STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT6A PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT6A PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT8 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R2C TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STRN3 TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2 STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2 STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PPP2CA STK24 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK24 STRN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK24 STRN3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK24 STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 VBP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CB PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 FZR1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN4 PFDN5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN4 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN6 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IGBP1 PPP2CB â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IGBP1 PPP2CA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 CDC20 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ACTR3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
YWHAZ ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19933840 20936779 25852190 20052757
ARAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 21988832 18039929 24746704 16189514 32296183 25852190 21779497 11909642
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
TBK1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 18353649 17327220 16858409
IKBKE IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 25225665 9786932 15210742 22787218 10893229 26712804 16127453 12702806 16380379 15367631 12692549 17706453 16199137 16914100
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
IKBKE TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 24622840 16858409
IRAK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15767370 17457343 21903422
TBK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 17599067 9786932 15210742 22787218 26712804 16127453 12702806 15367631 12692549 16380379 17706453 16199137 16914100
MYC PDK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 11283613 11283614 11704864 16517405 16517406 17055429 17558397 17785433 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
PGR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8701093 9408078 22396492 9305935 22892083 10651641
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
MYC NME1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18628958 12695333 14519204 16440314 11960382 11983916 18414489
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
PPP2CB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16987807 16680151 15048125
PPP2CA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151 15048125
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MAPK8 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 10551811 17081983 18767875 20068231 91332050 1651323 1748630 16713569 11243879 18669648 15210690
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11960382 17093053
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
AKT1 VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16551632 19335618 16027165
IGBP1 PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23892082 21988832 20092282 16085932 18782753 24484909 28330616 9647778 21454489 26496610 32296183 24145130 19156129 11371618 10441131
TRIB3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30071535 12791994
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
LCK ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9500442 10571988 25386784 11145737 7539106 27748765
ITGA4 FYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
TGFBR2 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 14557817 15265520 16474430 17934056 20060931 20519943 21614932 22703233 24132110 24336330
ILK TGFBR2 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 11696562 15905178 24527345 25100717 25268583 27111285
TGFBR2 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 10678166 9463378 11792802 11133108 19920116 14557817 11278410 15178549 20060931 17934056 21614932 8980228 9311995 20519943 21900405 15548370 19010789 15104092 16474430 30093905 11274345 9865696
ILK SMAD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11696562 15905178 24527345 25100717 25268583 27111285
PRKACA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19007248 11971957 20166139 18767875 20230923 9001246 10576742 23331499 20068231 7935389 18669648 18691976 9922370 15664191 19651622 12801936 9091312 10862777 9710607 11997508
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
YWHAZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
WDR83 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15118098 23331499
PPP2CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18039929 7604263 16680151 16239230 10995457 18042541 18588945
RAF1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 7565670 12750173 18799465 16364241 11909642 19219045 21988832 23331499 15342917 8933152 9671314 8393135 9808624 8223433 16189514 18988627 18669648 19541618 16293107 10969079 10567369 8157000 11136732 11948414 7898932 9069260 18039929 19369195 8607979 10327068 17116858 24746704 12920017 16129686 19058874 15466214
RAF1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
PRKACA ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21224395 20166139 18578522 23979717 31562188 18583710 18707149 17603879 19401330 12837751 11533025
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC3 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
PPP4C HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15805470
ESR1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12726856 14500345 17893710 19383788 19593637 20101232
MAP4K1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8824585 23331499 9003777
MAP3K1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12228228 9405400 25241761 10465784 15757900 15299005 14500727 21152872 26538579
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
PTPA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21159657 18039929 19216069 23109003 10026142 10995457 18042541 20452955 18559511 18588945 16680151 19405949 16227604 16406523
TNK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22322295 11394904 25678401 20333297 10652228
PTK6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20606012 15994200 15539407
PDK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12176337 15743829 12682057 11445557 15899889 12149249 10833263 15718470 11278835 10226025 11087733 14500673 16341064 19897009 9368760 24012393 11825911 9512493 9736715 11313365 9868760 15364915
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
PPP2R2A AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 18588945 16680151 20360384 16406523
PPP2CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15367694 11087733 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 8650155 18588945 16680151 11812651 20360384 16406523
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
TBK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21329883 21464307 21106850
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 11756412 9705322 11923280 16697215 20398329 18372248 12865427 15071501 15808505 20138985 20214616 15883165 15169778 10949026 12861023 11715018 18636226 9812896 17680028 11956222 10722653 20832730 18570873 16376338 17052453
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 ATXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15757972 15824120 17540008 34302818 24903464 29212253 33709453 12741986 17570479 21722762 29758256 23719381 20037628 23213356 12757707 24858692 20477910
CDK5 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12202491 9122166 17202132
CDK5 PRKN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19399218 24486837 17327227 19050041 29899409
CDK5 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 18833287 15178331 15917097 11877420 17085446 16554819 21947912 8131745 11517218 17459339 14970211 10341243 16705182 24610780 22112898 8764598 14557249 16223726 19455415 19090995 10936190 11146006 15944381
CDK5 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25799558 16782707 32668197 18691976 15911879 19413330 17611284
PDK1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8395513 15533936 18691976 9707564 12372837
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
PRKACA HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22865920 20716686
MAPK8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12917434 14970211 24610780 20122754 15936948
PPP2CA ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
PPP2CA MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945 20626350
PRKACA STK24 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10644707
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
PRKACA PTPRR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11749379 10601328
PRKACA YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 29109150 11956222 12861023 16376338 19451227
FYCO1 MAP1LC3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27246247 26468287 20562859
MAP3K3 MAP2K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 12912994 23331499 25241761 16861740 19903815 14743216 11073940 16189514 17985933 24975362 10593883 25861671 12813044
STRN ESR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11689445 15705661 18206197 11369763 28539435 22266855 22446104
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
MAPK8 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 18985696 25862939 15696159 11956222 19788416 21081103 15071501 18559254 7890696
FYCO1 MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27246247 26468287 20100911 20562859
ESR2 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16293641 12761896 11014241 19001520 9717846
PEX7 PEX14 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376